27 research outputs found
Comparison of Fluoride Ion Release from Fluoride Gel in Various Solvents
Cilj: U istraživanjuse željela odrediti koncentracija fluorida u razliÄitim otapalima i usporediti je s de-klariranom koncentracijom fluorida.Materijal i metode: Gel koji sadržava aminofluorid i natrijevfluorid usporeÄen je s gelom samo s natrijevim fluoridom. Otapala koriÅ”tena u ovom istraživanju bila su destilirana voda, redestilirana voda, voda iz slavine, 0,9-postotna otopina natrijeva klorida i umjet-na slina. KoliÄina fluoridnih iona (F -) odreÄena je fluor-selektivnom elektrodom. KoriÅ”teni su ANOVA i post hoc Tukeyjev test. Razina znaÄajnosti bila je Ī± = 5 %.Rezultati: Razlike izmeÄuotpuÅ”tanja F āiona u razliÄitim otapalima bile su statistiÄki znaÄajne (p < 0,05). Koncentracija F āiona izmjerena u otopinama redistilirane vode obaju gelova bila je viÅ”a od deklariranih koncentracija. Zabilježena je znaÄajna razlika u otpuÅ”tanju fluorida izmeÄu otopina gela koje su sadržavale samo natrijev fluorid. OslobaÄanje fluoridnih iona bilo je znaÄajno razliÄito u otopinama kombiniranoga fluoridnog gela. ZakljuÄak: Aminofluoridi ne stupaju u interakciju s drugim ionima u otopini, a otpuÅ”tanje F āiona iz natrijeva fluorida mijenja se kada su u istoj otopini i drugi ioni. Aminofluoridi uÄinkovitije dostavljaju F āione za prevenciju karijesa.Objective: The aim of this study was to determine the concentration of fluoride ions present in var-ious solvent solutions and compare it to the label amount of fluoride concentration. Material and methods: The gel containing amine fluoride and sodium fluoride was compared to gel containing sodium fluoride only. The solvents used in this study were distilled water, redistilled water, tap water, 0.9% sodium chloride solution and the artificial saliva. The amount of fluoride ion (F -) was determined by the use of fluoride ion-selective electrode. The ANOVA and the Post hoc Tukeyās test were used. The significance level was Ī± = 5%. Results: The differences between F āion release in various solvents were statistically significant (p < 0.05). The F āion concentrations measured in both gelsā redistilled water solutions were higher than the label concentration. There was a significant difference in fluo-ride ion release in sodium fluoride only gel solutions. Fluoride ion release was significantly different in combined fluoride gel solutions. Conclusions: Amine fluorides do not interact with other ions pres-ent in the solution, whereas F āion release from sodium fluoride alters when other ions are dissolved in the same solution. Amine fluorides deliver F -ions for caries prevention more efficientl
Influence of Smoking on the Periodontal Status of Adolescents
Mnoga su istraživanja potvrdila da je puÅ”enje jedan od najvažniji Äimbenika rizika za nastanak, progresiju i uspjeÅ”nu terapiju parodontalne bolesti. No samo je nekoliko istraživanja provedeno da bi se utvrdio utjecaj puÅ”enja na mlaÄu populaciju. Poznato je da je težina parodontalne bolesti izravno povezana s dnevnom koliÄinom cigareta, ali i s godinama puÅ”enja. Potrebno je prepoznati prve znakove negativna utjecaja kako bi se moglo djelovati.
Svrha ovoga istraživanja bila je odrediti postotak puÅ”aÄa meÄu uÄenicima, utvrditi ima li razlike u parodontalnom statusu puÅ”aÄa i nepuÅ”aÄa, te ustanoviti utjecaj puÅ”enja na gubitak priÄvrstka.
Istraživanje je provedeno na 517 srednjoÅ”kolskih uÄenika.
Uzimani su podatci o dobi, mjestu stanovanja. socijalnom statustu, navici puÅ”enja, navici puÅ”enja roditelja, navikama oralne higijene i posjeta stomatologu. Parodontalni se je status prikupljao s pomoÄu CPI i LA indeksa. 34,6% ispitanika bili su redoviti puÅ”aÄi. Dob u kojoj srednjoÅ”kolci poÄinju puÅ”iti sve je niža. Oni koji sada imaju 16 godina poÄeli su puÅ”iti s 14, ali oni koji sada imaju 14 i 15 godina poÄeli su puÅ”iti s 12. Djeca kojima roditelji puÅ”e imaju dvostruko veÄu vjerojatnost da i sami postanu puÅ”aÄi, u usporedbi s onom djecom kojoj roditelji ne puÅ”e. Krvarenje je ÄeÅ”Äe u puÅ”aÄa (4,61) nego nepuÅ”aÄa (4,19) (p=0,001).PuÅ”aÄi imaju znatno viÅ”e sekstanata s kamencem (1,47) nego nepuÅ”aÄi (0,88) (p<0,001). Gubitak priÄvrstka
znatno je veÄi u puÅ”aÄa (1,68) nego nepuÅ”aÄa (,59) (p<0,001). KoliÄina popuÅ”enih cigareta ima velik utjecaj na gubitak priÄvtstka. GodiÅ”nji gubitak priÄvrstka u redovitih i jakih puÅ”aÄa iznosi 0,07 mm. Navike oralne higijene ne razlikuju se izmeÄu puÅ”aÄa i nepuÅ”aÄa, ali uÄenici s loÅ”om oralnom higijenom imaju veÄi gubitak priÄvrstka.
PuÅ”enje utjeÄe na parodontalnu bolest, Äak i u mladoj populaciji.
Zato je prijeko potrebno obavijestiti mlade puÅ”aÄe o negativnim posljedicama te navike.Different studies have proven that smoking is one of the most important risk factors for the occurrence, progression and successual therapy of periodontal disease. However, only few studies have been conducted to prove the influence of smoking in a younger population. As we know that the severity of periodontal disease is directly
associated with the amount of daily smoked cigarettes and also with the duration of smoking, it is important to find out when the first signs of negative influence appear so that we can act appropriately.
The aim of this study was to determine if the periodontal status of smokers and non-smokers has differences, and to establish the influence of smoking habits on loss of attachment.The study was conducted on 517 highschool students. For each examinee data was taken concerning their age, place of residence, social status, smoking
habits, smoking habits of their parents, oral hygiene habits and attendance to a dentist. The periodontal status was measured by the CPI and LA indices. Among the examines 34.6% were regular smokers. Students who are now 16 started to smoke when they were 14, but students who are now 14 and 15 started at age of 12. Children whose parents smoke had a two-fold increase of becoming smokers themselves, compared to children whose parents did
not smoke. Bleeding was more frequent in non-smokers (4.61), than in smokers (4.19) (p=0,001). Smokers had significantly more sextants with calculus (1.47) than nonsmokers (0.88) (p<0,001). Loss of attachment was significantly greater in smokers (1.68) than in non-smokers (1.59) (p<0.001). The amount of smoked cigarettes had a great influence on loss of attachment. The annual loss of attachment in regular and intensive smokers measured 0.07 mm. Oral hygiene habits did not differ between smokers and non-smokers, but students with poor oral hygiene habits had greater attachment loss. Smoking has an influence on periodontal health even
in this young age population, therefore it is necessary to inform young smokers about the negative cosequencese that smoking has
Auto-Medication of Analgesics by Dental Patients
Uklanjanje boli jedan je od glavnih izazova stomatoloÅ”ke prakse. Akutna bol znaÄajka je veÄine odontogenih boli i Äesto je povezana sa samoupotrebom analgetika. No samolijeÄenje stvara rizik uzimanja prekomjerne doze lijeka, preduge upotrebe, kliniÄki znatnih interakcija s veÄ pripisanim lijekovima, te polipragmazije i moguÄih Å”tetnih uÄinaka. PoÄetno zbivanje kod veÄine bolnih stanja jest bolni podražaj koji izaziva destrukciju tkiva, sintezu i otpuÅ”tanje bikemijskih medijatora koji sudjeluju u nastanku boli. Za ublažavanje boli najÄeÅ”Äe se rabe analgeticiantipiretici, nesteroidni (NES) lijekovi koji djeluju na periferiji. Oni inhibiraju biokemijske medijatore boli. Svi NES analgetici izazivaju kvalitativno sliÄne neželjene uÄinke, uzimaju se kroz usta i lako su dostupni u ljekarnama bez recepta - u slobodnoj prodaji.
Svrha ovoga rada bila je odrediti ÄestoÄu samolijeÄenja analgeticima stomatoloÅ”kih bolesnika s akutnom boli. 32 bolesnika sa zuboboljom u dobi od 19 do 73 godine, prosjeÄne dobi 32,5 godine i oba spola, ispitana su o intenzitetu boli prije lijeÄenja i o uporabi lijekova. 68% bolesnika opisalo je svoju bol kao jaku, 21,9% kao umjerenu i 10,1% kao neugodni osjeÄaj. Rezultati su pokazali da je 99,6% bolesnika samo uzelo lijek za neposredno otklanjanje bolova. NajÄeÅ”Äe uzeti analgetici jesu: kombinacija analgetika- antipiretika (propifenazon+paracetamol+kofein+kodein) u 33% i dikofenak (Voltaren) u 29,1%, zatim metamizol u 21,8, aspirin u 13% i ibuprofen u 3,1% sluÄajeva. 56% bolesnika lijekove je nabavilo kod ljekarnika, a 44 % iz kuÄne zalihe. Bolesnici (87,5%) su dobro obavijeÅ”teni o moguÄim neželjenim uÄincima i toksiÄnosti NES analgetika. Neželjene uÄinke opisalo je 21,8% bolesnika, veÄinom kao gastrointestinalne simptome: muÄnina i želuÄana bol. To je u skladu s dobro opisanim nuspojavama NESanalgetika, koje su najvjerojatnije rezultat inhibicije ciklooksigenaza i znatan uzrok bolesti.Pain is one of the major challenges in dental care. The most common types of odontogenic pain are characterised as acute pain which is frequently associated with selfmedication with analgesics. However , there is a risk with self-medication such as the use of excessive drug dosage, prolonged duration of use, clinically significant interactions with prescription medicines and polypharmacy and possible side effects. The initial event for most painful conditions is a noxious stimulus that results in tissue destruction, the synthesis and the release of biochemical mediators involved in the pain process. Peripherally acting nonsteroid analgesic-antipyretic drugs /NSAIDs/ are the most commonly used analgesics. They inhibit these biochemical mediators of pain. All NSAIDs share a qualitatively similar side ellect profile, the oral route of administration and all of them are freely available to the general public without prescription over the counter drugs (OTC).
The aim of this study was to determine the incidence of auto medication with analgesics among dental patients with acute pain. 32 patients aged from 19 to 73 years, (32.5) of both sexes and with odontalgia were interviewed personally regarding the intensity of their pre-treatment pain and the use of medications. 68% of patients described their pain as severe, 21.9% as moderate pin and 10.1% as unpleasant sensation. The results showed that 99.6% of the patients self-medicated a drug for the immediate relief of toothache. The most frequently self-medicated analgesics were: analgesic-atipyretic combined formulations (propiphenazon + paracetamol + coffeine + codeine) in 33% and diclofenac (Voltaren) in 29.1%, the metamizol in 21.8%, aspirin in 13% and ibuprofen in 3.1%. Selfmedicated drugs came from the pharmacist in 56% patients and 44% from the family stock. Patients (87.5%) were well informed about possible side effects and toxicity of NSAIDs. Adverse effects during therapy was reported by 21.8% patients, mainly as gastrointestinal symptoms: nausea and gastric pain. This is in egreement with the wel documented NSAIDs side effects which are presumably the result of inhibiting cyclooxygenases and a significant cause of morbidity
The Effect of Salivary Calcium and Fluoride Toothpaste on the Formation of KOH-Soluble Fluoride: In Vitro Study
Svrha: Svrha ovoga preliminarnog istraživanja in vitro bila je procijeniti uÄinak sline puÅ”aÄa (pretpostavlja se da sadržava veÄu koncentraciju kalcija) u kombinaciji s fluornom pastom za zube na ugradnju alkalno topljivih fluorida na povrÅ”inu cakline. Materijali i metode: Sa svakoga od 14 ekstrahiranih impaktiranih umnjaka odrezana su Äetiri caklinska bloka koji su nakon toga nasumiÄnim odabirom svrstani u Äetiri skupine. Uzorci nestimulirane sline prikupljeni su od dvojice dobrovoljca istoga spola i dobi ā jedan je bio puÅ”aÄ, a drugi nepuÅ”aÄ. Dva uzorka iz skupine A i B muÄkala su se pet minuta u slini (A ā u slini puÅ”aÄa, B ā u slini nepuÅ”aÄa), a zatim tri minute u smjesi paste za zube i deionizirane vode (1 : 3). Uzorci iz skupina C nisu bili tretirani slinom nego su se muÄkali samo u smjesi paste za zube i deionizirane vode. Tretman je ponovljen poslije Å”est sati. Jedna od skupina (D) poslužila je kao kontrolna. Rezultati: Koncentracija kalcija u slini puÅ”aÄa bila je veÄa negoli u slini nepuÅ”aÄa. Ugradnja alkalno topljivih fluorida na povrÅ”inu cakline u skupini A bila je statistiÄki znaÄajno veÄa nego u ostalim dvjema tretiranim skupinama (B i C). Ugradnja alkalno topljivih fluorida na povrÅ”inu cakline u sve tri skupine koje su bile tretirane slinom i zubnom pastom bila je statistiÄki znaÄajno veÄa negoli u kontrolnoj skupini. ZakljuÄak: Rezultati pokazuju da slina puÅ”aÄa, koja je imala veÄu koncentraciju kalcija, poveÄava ugradnju alkalno topljivih fluorida na povrÅ”inu cakline, Å”to nas potiÄe da provedemo opsežniju studiju.Objective: The aim of this in vitro preliminary study was to assess the effect of smokersā saliva (assuming their higher calcium concentration) in combination with fluoridated toothpaste on the enamel uptake of alkali-soluble (KOH-soluble) fluoride. Materials and methods: Four enamel slabs were cut from each of 14 impacted third molars and randomly assigned into 4 groups. Unstimulated saliva samples were collected from two age and sex matched volunteers. One of the samples was taken from a heavy smoker and the other sample was taken from a non-smoker. Two groups (A and B) were shaken in saliva (A in smokerās saliva, B in nonsmokerās saliva) for 5 min and then shaken for 3 min in a toothpaste/deionized water slurry (1:3 w/w). One of the groups (group C) received no saliva treatment and was only shaken in toothpaste slurry for 3 min. The treatment was repeated after a 6-hour period. One of the groups (D) served as a control group with no treatment. Results: Calcium concentration in the smokerās saliva was higher than in the nonsmokerās saliva. The enamel uptake of KOH-soluble fluoride in group A was significantly higher than that in the other two treatment groups, B and C. The enamel uptake of KOH-soluble fluoride in all 3 groups was statistically different from that in the control group. Conclusion: These results demonstrate that saliva collected from a heavy smoker, which had higher salivary calcium concentration, enhances enamel uptake of alkali-soluble fluoride and encourages us to conduct a large-scale study
Fluoride-Releasing Restorative Materials: the Effect of a Resinous Coat on Ion Release
Svrha rada: Cilj istraživanja bio je utvrditi uÄinak dvaju dentinsko adhezijskih sustava i staklenoionomerne smole na koliÄinu otpuÅ”tenih fluoridnih iona i promjenu pH tijekom 168 dana. Materijali i metode: U istraživanju su koriÅ”tena Äetiri restaurativna materijala: giomer Beautifil II, alkasitni kompozitni materijal Cention, konvencionalni kompozit Filtek Z 250 i konvencionalni staklenoionomerni cement Fuji IX Extra. Svjetlosno polimerizirani kompozitni uzorci premazani su G-aenial Bondom i adhezivom Clearfil Universal Bond Quick. Na uzorke sa staklenoionomernim cementom nanesen je premaz GC Fuji Coat LC. Uzorci bez premaza koriÅ”teni su kao referencije. Mjerenja koliÄine otpuÅ”tenih fluoridnih iona i pH vrijednosti provedena su u sljedeÄim vremenskim intervalima: 1 sat, 24 sata, 2 dana, 7 dana, 28 dana, 84 dana i 168 dana. Rezultati: Kumulativne koliÄine otpuÅ”tenih fluoridnih iona poslije 168 dana poveÄale su se na nepremazanim uzorcima sljedeÄim redoslijedom: Filtek Z 250 < Beautifil II < Cention < Fuji IX Extra. Kompoziti premazani Clearfil Universal Bond Quickom otpuÅ”tali su manju koliÄinu fluoridnih iona od nepremazanih uzoraka, a kumulativne vrijednosti dosegnute nakon 168 dana poveÄavale su se sljedeÄim redoslijedom: Filtek Z 250 < Beautifil II < Cention. Kompoziti premazani G-aenial Bondom takoÄer su otpuÅ”tali manje koliÄine fluoridnih iona u usporedbi s nepremazanim uzorcima ā kumulativne vrijednosti poveÄavale su se sljedeÄim redoslijedom: Filtek Z 250 < Beautifil II < Cention. Kompoziti premazani G-aenial Bondom u svim su skupinama pokazivali pH vrijednosti u kiselom rasponu (4,4 ā 5,7) u intervalima od jednoga i 24 sata. ZakljuÄak: KoliÄina otpuÅ”tenih fluoridnih iona varirala je meÄu ispitivanim restaurativnim materijalima i ovisila je o upotrebi dentinskog adhezijskog sustava i premaza. Vrijednosti pH varirale su izmeÄu materijala, tretmana i vremenskih intervala.Objective: To determine the effect of two adhesive systems and a glass ionomer coating resin on fluoride release and concurrent pH changes over a period of 168 days. Material and methods: Four restorative materials were investigated: a giomer Beautiful II, an āalkasiteā material Cention, a conventional composite Filtek Z250, and a glass ionomer cement Fuji IX Extra. Light-cured composite specimens were coated using G-aenial Bond and Clearfil Universal Bond Quick. Glass ionomer specimens were coated using GC Fuji Coat LC. Uncoated specimens were used as references. Quantitative fluoride release and pH changes were measured after 1 h, 24 h, 2 days, 7 days, 28 days, 84 days, and 168 days. Results: The cumulative fluoride release after 168 days increased for uncoated specimens in the following order: Filtek Z250 < Beautifil II < Cention < Fuji IX Extra. A comparatively lower fluoride release was measured for the composites coated with Clearfil Universal Bond Quick, with cumulative values after 168 days increasing in the following order: Filtek Z250 < Beautifil II < Cention. The composites coated with G-aenial Bond showed lower fluoride release compared to the uncoated specimens, with cumulative values increasing in the following order: Filtek Z250 < Beautifil II < Cention. The composites coated with G-aenial Bond showed pH values in the acidic range (4.4-5.7) after 1 h and 24 h. Conclusion: Fluoride release varied among the investigated restorative materials and depended on the use of dental adhesives and coatings. The pH of all materials, coating types and time points varied
Antibiotic Administration Along with Endodontic Therapy in the Republic of Croatia: a Pilot Study
Cilj: Željelo se procijeniti vrstu i uÄestalost primjene antibiotika tijekom endodontskih zahvata u Republici Hrvatskoj te procijeniti stajaliÅ”te lijeÄnika dentalne medicine o endodontskom lijeÄenju pacijenata riziÄnih za nastanak bakterijskog endokarditisa.Materijal i metode: Podatci su skupljeni ispunjavanjem anketnih upitnika. Rezultati: MeÄu lijeÄnicima koji su odgovorili na anketna pitanja njih 8,4 % istaknulo je da propisuje antibiotike Äesto, a 91,6 % nikada, vrlo rijetko ili rijetko. VeÄina njih (41 %) ordinirala je antibiotike jedanput ili dva puta na mjesec, 32,5 % jedanput ili dva puta u nekoliko mjeseci, a 20,5 % jedanput ili dva puta na tjedan. NajÄeÅ”Äe koriÅ”teni antibiotik bio je penicilin s klavulanskom kiselinom. Zatim, 26,2 % lijeÄnika propisivalo je antibiotike za gangrenu pulpe, 51,2 % za lokalizirani akutni apikalni parodontitis bez otekline, 85 % za celulitis, 75 % za poviÅ”enu tjelesnu temperaturu i poveÄane limfne Ävorove, 16,9 % za zub s fistulom i 94,1 % za profilaksu bakterijskog endokarditisa. Prema rezultatima studije 54,4 % stomatologa nije propisivalo antibiotike bez intervencije na osjetljivom zubu, 76 % Äesto je, gotovo uvijek, ili uvijek prihvatilo endodontsko lijeÄenje bolesnika kojima je bila potrebna antibiotska profilaksa zbog sprjeÄavanja infektivnog endokarditisa, a 96,7% sudionika odgovorilo je da zna za nedavne upute o antibiotskoj profilaksi.ZakljuÄak: Rezultati upozoravaju na neprimjerenu uporabu antibiotika u praksi na temelju odgovora 83 doktora dentalne medicine, s obzirom na uÄestalost primjene i indikacije. NajÄeÅ”Äe koriÅ”teni antibiotik bio je penicilin s klavulanskom kiselinom. Visok postotak anketiranih odgovorio je da su im poznate recentne upute o antibiotskoj profilaksi te da obavljaju endodontske zahvate i pacijentima riziÄnima za razvoj bakterijskog endokarditisa. Potrebna je ciljana trajna edukacija doktora dentalne medicine u Republici Hrvatskoj.Objective: To evaluate the type and the frequency of antibiotic prescribing along with endodontic therapy in Croatia. The aim is, also, to assess the attitudes of Croatian doctors towards endodontic treatment of patients at risk of developing bacterial endocarditis. Material and methods: Data were collected by a survey questionnaire. Results:8.4% of the examined practitioners stated that they prescribe antibiotics often, and 91.6% of them stated that they prescribed them never/ very rarely/rarely. Most of them (41%) prescribe antibiotics once or twice a month, 32.5% once or twice in several months and 20.5% once or twice a week. The most commonly used antibiotic was penicillin with clavulanic acid. Also, 26.2% of examined practitioners prescribed antibiotics for gangrene pulp, 51.2% of them for localized acute apical periodontitis without swelling, 85% of them for cellulitis, 75% of them for fever and enlarged lymph nodes, 16.9% of them for tooth with fistula and 94.1% of them for prophylaxis of infectious endocarditis. According to the results of study, 54.4% of dental practitioners did not prescribe antibiotics without intervention on susceptible tooth; 76% of participants often/almost always/ always accepted endodontic treatment of patients requiring antibiotic prophylaxis to prevent infectious endocarditis, and 96.7% of participants indicated they were familiar with recent instructions for antibiotic prophylaxis. Conclusion: These findings point to inappropriate use of antibiotics in the practice of 83 dental practitioners questioned regarding the frequency of administration and indications. The most commonly used antibiotic was penicillin with clavulanic acid. A high percentage of surveyed practitioners stated that they were familiar with recent instructions for antibiotic prophylaxis. They also stated that they performed endodontic procedures on patients who were at risk of bacterial endocarditis. There is a noticeable need for targeted continuing education of dental practitioners in the Republic of Croatia
Use of antiseptics in pediatric dentistry
Svrha ovog rada je pregled antiseptika i defi niranje znaÄenja stomatoloÅ”kih antiseptika u kontroli i eliminaciji mikroorganizama kao
sastavnog dijela prevencije i terapije bolesti zuba i parodonta u djeÄjoj stomatologiji. Dosad su poznate karakteristike i mehanizam
djelovanja pojedinih antiseptika te je doprinos rada predstaviti indikacije za njihovu primjenu u svakodnevnom radu stomatologa,
osobito u djeÄjoj i preventivnoj dentalnoj medicini.The purpose of this article is to review the use of antiseptics and defi ne the meaning of dental antiseptics in the control and elimination
of microorganisms as an integral part of prevention and treatment of plaque diseases in pediatric dentistry. Also, the article
describes the known characteristics and mechanism of action of some antiseptics, contributing to current indications for their use in
pediatric and preventive dentistry
Znanje i stajaliÅ”ta doktora dentalne medicine u Hrvatskoj o propisivanju antibiotika u endodonciji: presjeÄno istraživanje
Objectives: To assess dentistsā level of knowledge and practice concerning antibiotic usage in endodontics using the European Society of Endodontology position statement as a reference. Material and Methods: A cross-sectional study was conducted in the form of an electronic questionnaire consisting of 23 questions, including dentistsā demographic and professional characteristics, attitudes as well as experiences regarding antibiotics in endodontics. Data were evaluated by the Mann-Whit-ney test or the Kruskal Wallis 1-way ANOVA, Ī± = 5%. Results: The overall mean self-reported knowl-edge of antibiotics usage in endodontics was 11.7Ā±2.5 points, out of a maximum possible score of 23. The factors associated with a higher knowledge were: age (Pā¤0.001), clinical experience (Pā¤0.001), specialist training (P=0.008), and adherence to the guidance on the use of systemic antibiotics in endodontics (P=0.006). Dentists who specialized in endodontics (16.1Ā±2.2) achieved higher levels of knowledge. Conclusion: Knowledge on antibiotic usage in endodontics among dentists in Croatia is insufficient. There is a need for continuing education on the use of antibiotics among general dentists.Ciljevi: Procijeniti razinu znanja i iskustva stomatologa o primjeni antibiotika u endodonciji koristeÄi se kao referencijom konsenzusom Europskoga endodontoloÅ”koga druÅ”tva. Materijal i metode: Ovo presjeÄno istraživanje provedeno je na temelju elektroniÄkoga upitnika sastavljenoga od 23 pitanja, ukljuÄujuÄi demografske i profesionalne znaÄajke doktora dentalne medicine, njihova stajaliÅ”ta i iskustva u vezi s koriÅ”tenjem antibiotika u endodonciji. Podatci su analizirani Mann-Whitneyjevim testom ili Kruskal-Wallisovim jednosmjernim ANOVA testom ā Ī± = 5 %. Rezultati: Ukupna prosjeÄna vrijednost znanja doktora dentalne medicine iznosila je 11,7 Ā± 2,5 bodova, od najviÅ”e moguÄih 23. Äimbenici povezani s viÅ”im znanjem bili su dob (P ā¤ 0,001), kliniÄko iskustvo (P ā¤ 0,001), specijalistiÄko usavrÅ”avanje (P = 0,008) te poÅ”tovanje smjernica o primjeni sistemskih antibiotika u endodonciji (P = 0,006). Doktori dentalne medicine koji su specijalizirali endodonciju (16,1 Ā± 2,2) postigli su viÅ”u razinu znanja. ZakljuÄak: Znanje o primjeni antibiotika u endodonciji meÄu doktorima dentalne medicine u Republici Hrvatskoj je nedostatno. Potrebna je stalna edukacija o upotrebi antibiotika meÄu populacijom opÄih doktora dentalne medicine