Histological Classification of 956 NSCLC samples

<p>A. Classification of Resection Samples B. Classification of Small Biopsies/cytology samples and C. Metastasis Samples according to IASLC/ATS/ERS 2011, WHO 2015.</p

KRAS mutations distributed amongst different Adenocarcinoma groups.

<p>KRAS mutations distributed amongst different Adenocarcinoma groups.</p

Frequencies of alterations between different groups of adenocarcinomas (NL = Normal, MT = Mutant, AMPL = gene amplification).

<p>Frequencies of alterations between different groups of adenocarcinomas (NL = Normal, MT = Mutant, AMPL = gene amplification).</p

Schematic representation of the distribution (%) of different KRAS mutations.

<p>Schematic representation of the distribution (%) of different KRAS mutations.</p

Pie charts representing the frequencies (%) of alterations of the examined genes in this cohort.

<p>Percentage of alterations for all the samples of the cohort (All NSCLC) and between the different histological types adenocarcinoma (AdCa), squamous cell carcinomas (Squamous), and other types (NOS and Other).</p

EGFR mutations distributed amongst different Adenocarcinoma groups.

<p>EGFR mutations distributed amongst different Adenocarcinoma groups.</p

Clinicopathological and demographic characteristics of NSCLC patients.

<p>Clinicopathological and demographic characteristics of NSCLC patients.</p

Additional file 19: Figure S11. of A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence

Hybridization probes incorporating nucleotide analogs based on the LNA technology. (PDF 144 kb