783 research outputs found

    Celebrating 125 years of the Queen's Tower

    Get PDF
    Celebrating 125 years of the Queen’s Tower, the only remaining part of the Imperial Institute, which was built to mark Queen Victoria’s Golden Jubilee in 1887, and opened in 1893

    High volume ergonomic simulation of chairs

    Get PDF
    To understand what makes a chair comfortable or practical we need to test a large number of chairs, both good and bad. Due to the numbers involved we cannot achieve this with physical testing. Instead we use simpli ed ergonomic simulations. The sim- ulations presented here produce pressure maps within the range given the literature, along with several other measures of comfort and practicality. This was done sub- stantially faster than examples in the literature, permitting collection of thousands of results

    Relationship-based access control: its expression and enforcement through hybrid logic

    Get PDF
    Access control policy is typically de ned in terms of attributes, but in many applications it is more natural to de- ne permissions in terms of relationships that resources, systems, and contexts may enjoy. The paradigm of relationshipbased access control has been proposed to address this issue, and modal logic has been used as a technical foundation. We argue here that hybrid logic { a natural and wellestablished extension of modal logic { addresses limitations in the ability of modal logic to express certain relationships. Also, hybrid logic has advantages in the ability to e ciently compute policy decisions relative to a relationship graph. We identify a fragment of hybrid logic to be used for expressing relationship-based access-control policies, show that this fragment supports important policy idioms, and study its expressiveness. We also capture the previously studied notion of relational policies in a static type system. Finally, we point out that use of our hybrid logic removes an exponential penalty in existing attempts of specifying complex relationships such as \at least three friends"

    Heavy Schistosomiasis Associated With Poor Short-Term Memory and Slower Reaction Times in Tanzania Schoolchildren

    Get PDF
    Cross-sectional studies of the relationship between helminth infection and cognitive function can be informative in ways that treatment studies cannot. However, interpretation of results of many previous studies has been complicated by the failure to control for many potentially confounding variables.We gave Tanzanian schoolchildren aged 9±14 a battery of 11 cognitive and three educational tests and\ud assessed their level of helminth infection. We also took measurements of an extensive range of potentially confounding or mediating factors such as socioeconomic and educational factors, anthropometric and other biomedical measures. A total of 272 children were moderately or heavily\ud infected with Schistosoma haematobium, hookworm or both helminth species and 117 were uninfected with either species. Multiple regression analyses, controlling for all confounding and mediating variables, revealed that children with a heavy S. haematobium infection had signi®cantly lower scores than uninfected children on two tests of verbal short-term memory and two reaction time tasks. In one of\ud these tests the effect was greatest for children with poor nutritional status. There was no association between infection and educational achievement, nor between moderate infection with either species of helminth and performance on the cognitive tests. We conclude that children with heavy worm burdens and poor nutritional status are most likely to suffer cognitive impairment, and the domains of verbal\ud short-term memory and speed of information processing are those most likely to be affected

    Vitamin K catabolite inhibition of ovariectomy-induced bone loss: Structure–activity relationship considerations

    Get PDF
    The potential benefit of vitamin K as a therapeutic in osteoporosis is controversial and the vitamin K regimen being used clinically (45 mg/day) employs doses that are many times higher than required to ensure maximal gamma‐carboxylation of the vitamin K‐dependent bone proteins. We therefore tested the hypothesis that vitamin K catabolites, 5‐carbon (CAN5C) and 7‐carbon carboxylic acid (CAN7C) aliphatic side‐chain derivatives of the naphthoquinone moiety exert an osteotrophic role consistent with the treatment of osteoporosis

    OPAL Community Environment Report

    Get PDF
    The Open Air Laboratories network, or OPAL, as it quickly became known, was launched in 2007 following a successful application to the Big Lottery Fund It was the first time that Big Lottery funding on this scale had been awarded to academic institutions. The University of Central Lancashire led by Dr Mark Toogood was responsible for understanding public engagement with OPAL. The Open Air Laboratories (OPAL)network is a nationwide partnership comprising of ten universities and five organisations with grants awarded totalling £14.4 million. • Over half a million people have participated in the OPAL programme. OPAL activities are carried out by people of all ages, backgrounds and abilities, including 10,000 people in ‘hard to reach’ communities. • OPAL opens people’s eyes to the natural world. Nearly half (44%) of OPAL survey participants said that this was the first time that they had carried out a nature survey. 90% of participants have learnt something new. • OPAL has the ability to change people’s behaviour. Almost half (43%) of respondents said OPAL had changed the way they thought about the environment and more than a third (37%) said they will change their behaviour towards it. • In addition to raising environmental awareness, OPAL also improves personal well-being by motivating people to spend time outdoors doing something positive, while connecting with people and nature
    corecore