187 research outputs found
Pair production of heavy charged gauge bosons in collisions at LHC
Two opposite charged new heavy gauge boson pair production at the Large
Hadron Collider (LHC) is presented in this paper. These bosons are known as
boson due to the reason that it is the heavy version of Standard
Model's weak force carrier, the boson. The production cross section and
decay width in proton-proton () collision at \sqrts~= 8 TeV are calculated
for different masses and coupling strengths of . Efficiencies for
different signal regions and branching ratios for different decay channels are
computed. In this study, the pair production () is
considered in emerging new physics as a result of collision at \sqrts~= 8
TeV at the LHC with final state containing two tau () leptons and two
neutrinos (each decay to and its neutrino). The event selection
efficiency similar to the CMS experiment is used for the mass of to set
lower limits for different coupling strengths of and results are
presented in this work. For heavy gauge bosons, when coupling strength is
similar to that of Standard Model's boson, the mass of below 305
GeV are excluded at confidence level of .Comment: 21 pages, 16 figure
A Case of Persistent Asthma Resistant to Available Treatment Options: Management Dilemma
Asthma affects nearly 300 million people worldwide, with 250,000 associated deaths annually. An estimated 5%-10% of patients have severe asthma, while only 1%-2% presented with treatment-resistant or refractory asthma. Currently, the endotype of asthma is divided into T-helper type 2 (Th2) high and Th2-low inflammation endotypes. The Th2-high endotype is characterized by eosinophilic asthma, while the Th2-low endotype is associated with neutrophilia and a pauci-granulocytic profile. The Th2-low endotype carries a high resistance to corticosteroid and bronchodilator therapy, and these patients typically have a severe and acute-onset of symptoms. We present a 57-year-old nonsmoking female with recurrent intensive care unit (ICU) admissions for severe acute asthma exacerbations, resistant to bronchodilator and steroid treatment, requiring mechanical ventilation. Currently, the guidelines for treating neutrophil-predominant Th2-low inflammation asthma have not been established. This creates a management dilemma when encountered with such a patient in clinical practice. We aim to propose targeted treatment options for these severe and potentially fatal asthma patients, with reference to current literature
Viability of Split Thickness Autogenous Skin Transplantation in Canine Distal Limb Reconstruction – An Experimental Evaluation
Distal limb reconstruction is complicated by the paucity of local tissues and the frequent association of orthopedic injury with cutaneous loss. Though, second-intention healing or skin stretching techniques are used for wounds involving less than a 30% circumference of the limb, however, skin grafts are recommended for reconstruction of larger superficial wounds. The present study was designed to clinically evaluate the viability of split thickness autogenous skin transplantation (STAST) in dogs. Standardized surgical defects of variable size i.e. 3×3, 4×4 and 5×5 sq cm were made on the left middle radial area (forearm) of 15 mongrel dogs assigned to Group A, B and C, respectively having 5 dogs each. Split thickness autogenous skin grafts were harvested from mid thorax and placed in these defects through several simple interrupted sutures. Results indicated a success rate of 80% with no clinical difference in the survival rate of three different sizes of grafts used. Hence, STAST can successfully be used for canine distal limb reconstruction
Prevalence of active HCV infection among the blood donors of Khyber Pakhtunkwa and FATA region of Pakistan and evaluation of the screening tests for anti-HCV
Hepatitis C is a fatal liver disease caused by the hepatitis C virus. In this study, blood donors, from various districts of the KPK province and the federally administered tribal area (FATA) of Pakistan were tested for anti-HCV antibodies and HCV RNA by ICT (Immuno-chromatographic test), ELISA and RT-PCR. Out of the 7148 blood donors, 224 (3.13%) were positive for anti-HCV antibodies by ICT, 135 (1.89%) by ELISA while 118 (1.65%) blood donors had active HCV infection as detected by RT-PCR. We suggest that ELISA should be used for anti-HCV screening in public sector hospitals and health care units
Duplex PCR assay for the detection of avian adeno virus and chicken anemia virus prevalent in Pakistan
Avian Adeno viruses and Chicken Anemia Viruses cause serious economic losses to the poultry industry of Pakistan each year. Timely and efficient diagnosis of the viruses is needed in order to practice prevention and control strategies. In the first part of this study, we investigated broilers, breeder and Layer stocks for morbidity and mortality rates due to AAV and CAV infections and any co-infections by examining signs and symptoms typical of their infestation or post mortem examination. In the second part of the study, we developed a duplex PCR assay for the detection of AAV and CAV which is capable to simultaneously detect both the viral types prevalent in Pakistan with high sensitivity and 100% specificity
An approach to PLC in fast moving consumer goods: A case study from Pakistan
Fast moving consumer goods (FMCGs) is possibly the toughest and most disciplined of all industries. The survival, market share and profitability of a FMGC organization rely on number of factors including innovative thoughts, focused consumer, competitor analysis and deep marketing knowledge. These factors are necessary considerations throughout the Product Life Cycle (PLC). PLC analysis is considered to be a valuable tool for strategic planning for organizations and was first introduced to track the product's progress in all phases from introduction to disposal. FMCG organizations gain a competitive edge by using a product life cycle approach over those who do not use it. This paper presents a case study of a local FMGC organization and its approach to PLC. The study revealed that the PLC approach has significant effects on the success of the product in the market
Efficacy of mannan-oligosaccharide and live yeast feed additives on performance, rumen morphology, serum biochemical parameters and muscle morphometric characteristics in buffalo calves
The objective of the current study was to assess the effect of dietary
supplementations of mannan-oligosaccharide, live yeast, and a combination of
these two additives on growth performance, histo-morphology of the rumen, and
muscle morphometric attributes in buffalo calves. A total of twenty buffalo
calves (average weight of 25 kg) having 3 months of age were distributed
according to a complete randomized design. All animals were individually
stalled in the shed and were fed ad-libitum. Experimental animals were divided
into four groups for 67 days: Control group(without the inclusion of dietary
supplementation); MOS group (Mannan oligosaccharide 5 g/clave/day; Yeast group
(Live yeast 2g/calve/day) and Mixed group (MOS + Live Yeast 2.5g + 1g
)/calve/day. Experimental results revealed that combined supplementation of MOS
and Yeast and MOS alone resulted in an increased number of short-chain fatty
acids in the rumen as well as ruminal pH (P<0.05). Results showed a significant
improvement in average daily gain and FCR of MOS and Mixed supplemented groups
(P<0.05). Histomorphological evaluation of rumen mucosal epithelium showed a
significant improvement in the mixed-supplemented group (P<0.05) as compared to
the yeast-supplemented and control groups. Muscle quality parameters such as
meat texture showed significant improvement in MOS and mix-supplemented groups.
Histological examination of longissimus dorsi muscle cross-section showed a
significantly higher(P<0.05) muscle fiber and muscle fascicle diameter in both
MOS and mix-supplemented calves groups. In conclusion, the results of this
experiment revealed that the dietary addition of MOS, Live yeast, and their
combination have positive effects on growth performance, rumen histology
indices, and muscle morphometric features in buffalo calves.Comment: Pages 13, 4 figure
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