Trypanocidal efficacy of Allium sativum bulb extract, diminazene aceturate and their combination on experimental Trypanosoma brucei brucei infection in rats

The therapeutic activity of aqueous extract of Allium sativum (garlic) diminazene aceturate and their combinations were investigated in Wister albino rats infected with Trypanasoma brucei brucei. The criteria used in the assessment of the trypanocidal effects of the agents included the degree of parasitaemia observed daily for parasite, clinical changes during treatment and after treatment, possible death, haematological changes before and after treatment and frequency of relapse. . Rats treated with sub therapeutic dose of Allium sativum (20 mg/kg) and Diminazene aceturate (1.75 mg/kg) in combination remained parasite free throughout the 60 days of observation. Similar result was obtained in rats treated with diminazene aceturate (3.5 mg/kg) alone. However relapse parasitaemia occurred in rats treated with 40 mg/kg Allium sativum alone (

Trypanocidal effects of Securidaca longepedunculata root extract on Trypanosoma brucei and T. evansi

No Abstract.Animal Production Research Advances Vol. 4 (2) 2008: pp. 111-11

Physicochemical and Bacteriological Profiles of Borehole Water from Aliero Community of Kebbi State, Nigeria

Physicochemical and bacteriological analyses were carried out on four borehole water samples collected around Aliero community in Kebbi State, Nigeria. A total of thirteen parameters were determined. The conductivity results were high against the WHO standard with Gangire village having the highest (1664.0 us/cm) and Government Day Secondary School, Aliero (GDSS) having the lowest (1088.0 us/cm). The total hardness of General Hospital borehole sample was highest at 235.3 mgld, while that of GDSS was IS 146.0 mgl/d lowest, and exceeded the desirable WHO limits. Similarly, the concentrations of sodium, nitrates, bicarbonates, sulphates and chlorides were within the desirable WHO limits, while those of calcium, magnesium and phosphate are highly against the WHO desirable limit. The bacteriological analyses however indicated the highest bacterial count in Gangire village with 4.6x105 ctu/cm3, while the total coliform was 1320 mpn/100ml. Thus, the boreholes water from Kebbi State University of Science and Technology, Aliero Quarters (KSUST), GDSS and General Hospital were safer for drinking then that of Gangire village, while normal tap water was safer compared to these borehole water samples due to the latter’s pre-treatment process. Keywords: Borehole water, physicochemical property, bacterial count, Nigeri

In vitro antimicrobial activity of aqueous extracts of Argemone Mexicana on some pathogenic organisms

No Abstract. IJOTAFS Vol. 2 (2) 2008: pp. 156-15