ASSESSMENT OF EFFICACY IN APPLICATION OF TOPICAL IMMUNOLOGIC RESPONSE MODIFIER FOR PREVENTION OF INFLUENZA AND ACUTE RESPIRATORY INFECTIONS IN CHILDREN

The purpose of this work was to assess the efficacy of bacterial lysate for prevention of acute respiratory infections. The article provides results of monitoring children in the orphanage who were administered the medication of this group as a prophylactic drug against acute respiratory infections. Children also from orphanages who were not administered the medication were selected as a control group. It was found that out of 80 children who underwent preventive treatment, only 26 children fell ill, while out of 80 children in the control group so did 78 orphans. The results achieved allowed the topical immunologic response modifier to be recommended as a general preventive medication for wide use in children in the period of seasonal respiratory infection incidence rate pickup.Key words: influenza, acute respiratory infections, preventive treatment, children

MODERN EPIDEMIOLOGICAL PECULIARITIES OF HEPATITIS A AND EFFICACY OF UNIVERSAL VACCINATION IN CHILDREN

Authors described modern epidemiological peculiarities of hepatitis A in Russia. They prove reasonability of mass vaccination implementation against this infection. Results of a vaccination in children after its inclusion in Regional Calendars of Prophylactic Immunization are analyzed.Key words: children, hepatitis A, vaccinal prophylaxis, posvaccinal immunity.                 (Voprosy sovremennoi pediatrii — Current Pediatrics. – 2010;9(3):131-135

MODERN EPIDEMIOLOGICAL PECULIARITIES OF HEPATITIS A AND EFFICACY OF UNIVERSAL VACCINATION IN CHILDREN

Authors described modern epidemiological peculiarities of hepatitis A in Russia. They prove reasonability of mass vaccination implementation against this infection. Results of a vaccination in children after its inclusion in Regional Calendars of Prophylactic Immunization are analyzed.Key words: children, hepatitis A, vaccinal prophylaxis, posvaccinal immunity.                 (Voprosy sovremennoi pediatrii — Current Pediatrics. – 2010;9(3):131-135)</p

ОЦЕНКА ЭФФЕКТИВНОСТИ ПРИМЕНЕНИЯ ТОПИЧЕСКОГО ИММУНОМОДУЛЯТОРА ДЛЯ ПРОФИЛАКТИКИ ГРИППА И ОСТРЫХ РЕСПИРАТОРНЫХ ИНФЕКЦИЙ У ДЕТЕЙ

The purpose of this work was to assess the efficacy of bacterial lysate for prevention of acute respiratory infections. The article provides results of monitoring children in the orphanage who were administered the medication of this group as a prophylactic drug against acute respiratory infections. Children also from orphanages who were not administered the medication were selected as a control group. It was found that out of 80 children who underwent preventive treatment, only 26 children fell ill, while out of 80 children in the control group so did 78 orphans. The results achieved allowed the topical immunologic response modifier to be recommended as a general preventive medication for wide use in children in the period of seasonal respiratory infection incidence rate pickup.Key words: influenza, acute respiratory infections, preventive treatment, children.Целью работы была оценка эффективности бактериального лизата для профилактики острых респираторных инфекций. В статье приводятся результаты наблюдения детей, находящихся в доме ребенка, получавших препарат данной группы в качестве профилактического средства от острых респираторных инфекций. В качестве группы сравнения были выбраны также дети из дома ребенка, не получавшие препарата. Было показано, что из 80 детей, прошедших курс профилактики, заболели лишь 26, в то время как из 80 детей группы сравнения заболели 78 воспитанников детских домов. Полученные результаты позволили рекомендовать изучаемый топический иммуномодулятор в качестве средства неспецифической профилактики для широкого использования у детей в период сезонного подъема заболеваемости респираторными инфекциями. Ключевые слова: грипп, острые респираторные инфекции, профилактика, дети. (Педиатрическая фармакология. – 2009; 6(5):65-69

IS ROUTINE VACCINATION AGAINST HEPATITIS A NEEDED IN CHILDREN? EVALUATION OF PROPHYLAXIS WITH VACCINES IN SEVERAL REGIONS OF RUSSIAN FEDERATION

The article presents data on effectiveness of routine vaccination against hepatitis A in children. The results of program of specific prophylaxis of hepatitis A in several regions of Russian Federation are analyzed. Perspectives of implementation of obtained experience are discussed.Key words: children, hepatitis A, routine vaccination, regional vaccination calendars.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(6):123-126