The Effect of Epidural Analgesia Added to General Anesthesia on Systemic Immune-Inflammation Index in Radical Prostatectomy Surgery: A Retrospective Study

Background: Systemic immune-inflammation index (SII) is increasingly valued for its simplicity and predictability. Anesthesia/analgesia technique may affect cancer survey. Aims: The primary aim of this study is to offer a comparative evaluation for the effect of different anesthesia/analgesia techniques employed in radical prostatectomy surgery on SII, a new inflammatory index. Patients and Methods: Eighty-one patients who underwent radical prostatectomy between January 1, 2012, and December 31, 2020, were included in the study. We recorded oncological demographic data of Group G (n = 45) and Group GE (n = 36), preoperative and postoperative (within the first 4 hrs and 24th hr) SII values, perioperative surgical bleeding, and amount of blood transfusion. Results: Despite the lack of significant difference in the SII values between the groups, both the peak SII level and the SII change in the postoperative period became higher in Group G than in Group GE. In addition, the amount of surgical bleeding and blood transfusion was observed to be significantly lower in Group GE (P < 0.001, P = 0.092, respectively). Conclusions: GE in radical prostatectomy surgery in terms of SII, the SII change in the postoperative period was more pronounced in Group G. However, a significant difference was noted in surgical bleeding in Group GE. We can conclude that comparing the SII values of different anesthesia techniques with prospective studies might thus create a difference in survival and metastasis at the micro-level

The effects of noise levels on nurses in intensive care units

Background Intensive care units (ICUs) are noisy environments, which may have negative psychological effects on nurses. Aims and objectives To investigate the effects of the noise level of ICUs on nurses' burnout, job satisfaction, anxiety, psychological symptoms and general psychopathology level. Design A descriptive and correlational study. Methods The study was conducted with 150 intensive care nurses. A Type 2250-L Bruel & Kj AE r hand-held sound level meter was used for noise measurement. A Nurse Information Form, the Maslach Burnout Inventory, Minnesora Satisfaction Questionnaire, Self-Report Inventory and Symptom Checklist-90 Revised were used for data collection. Results The highest levels of noise (71 dB(A) and above) were measured in the neonatal, neurology and cardiovascular surgery ICUs. It was observed that noise level affected extrinsic satisfaction (F = 3 center dot 704; p = 0 center dot 027) and trait anxiety (F = 3 center dot 868; p = 0 center dot 023) of nurses. Conclusions Noise levels in ICUs are well above the recommended levels, and this affects nurses' job satisfaction and anxiety levels. Relevance to clinical practice More studies on the effects of noise levels on the physical and mental states of nurses working in ICUs are needed. Increased quality of patient care can be achieved by providing healthy working conditions for nurses working in special units such as ICUs