1,023 research outputs found

    Environmental tobacco smoke and children's health

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    Passive exposure to tobacco smoke significantly contributes to morbidity and mortality in children. Children, in particular, seem to be the most susceptible population to the harmful effects of environmental tobacco smoke (ETS). Paternal smoking inside the home leads to significant maternal and fetal exposure to ETS and may subsequently affect fetal health. ETS has been associated with adverse effects on pediatric health, including preterm birth, intrauterine growth retardation, perinatal mortality, respiratory illness, neurobehavioral problems, and decreased performance in school. A valid estimation of the risks associated with tobacco exposure depends on accurate measurement. Nicotine and its major metabolite, cotinine, are commonly used as smoking biomarkers, and their levels can be determined in various biological specimens such as blood, saliva, and urine. Recently, hair analysis was found to be a convenient, noninvasive technique for detecting the presence of nicotine exposure. Because nicotine/cotinine accumulates in hair during hair growth, it is a unique measure of long-term, cumulative exposure to tobacco smoke. Although smoking ban policies result in considerable reductions in ETS exposure, children are still exposed significantly to tobacco smoke not only in their homes but also in schools, restaurants, child-care settings, cars, buses, and other public places. Therefore, more effective strategies and public policies to protect preschool children from ETS should be consolidated

    Regional Community Building in Northeast Asia in a Global Context

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    In the context of power shift from Europe to Asia, Asia is creating a new history as the most dynamic region in the world. Historically, Asian countries have long maintained cultural and institutional connections within the region through constant contact, exchange, trade, and warfare. These cultural and institutional linkages serve as a cohesive factor for Asian countries to converge on regional commonness despite intraregional disparities. When looking at Northeast Asia, the center of Asian dynamism, the regions future is beset by serious challenges and threats, complicated by historical conflicts and territorial disputes. Building a regional community is crucial to turn tension and conflict to cooperation and coexistence in the region, but it is hampered by hegemonic competition under the rise of nationalism. As a way out, they should take both economic and cultural approaches toward the creation of regional community according to bilateral principles based upon one-to-one negotiations. In this regard, the non-expansionary stance of Korea so far gives her a moral hegemonic precedence over China and Japan in Northeast Asian community building.This work was supported by the National Research Foundation of Korea Grant funded by the Korean Government (NRF-2012-413-B00006)

    Effects of feeding ethanol on growth performances, carcass characteristics, and lipid metabolism of finishing Korean cattle (Hanwoo) steers

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    Objective The purpose of this study was to determine the effects of feeding ethanol on growth performances, carcass characteristics, and lipid metabolism of finishing Korean cattle (Hanwoo) steers. Methods Thirty (30) Hanwoo steers (average 25.1 months of age, body weight 660.1 kg) were assigned to three treatments: control (0% ethanol), E-3 (1.44% ethanol for 3 months), or E-5 (0.72% ethanol for 2 months followed by 1.44% ethanol for 3 months). The animals were allotted by treatment group into six pens and fed concentrate and perennial ryegrass. Ethanol (30%, v/v) was supplemented into drinking water twice a day to meet final concentrations based on average water consumption of finishing Hanwoo steers. Results There were no statistical differences among the groups in final body weight, average daily gain, or carcass yield grade indices such as cold carcass weight, fat thickness, and loin area. The marbling score tended (p = 0.228) to increase with the highest score (6.7) in the E-5 group followed by 6.3 and 6.0 in E-3 and control groups, respectively. The appearance frequencies of quality grades of 1++ (the best), 1+, 1, and 2, were; 30%, 50%, 0%, and 20% for control, 10%, 80%, 10%, and 0% for E-3, and 10%, 80%, 0%, and 10% for E-5 groups, respectively, indicating improvements of quality grades by feeding ethanol. Concentrations of serum glucose tended to decrease whereas those of insulin and non-esterified fatty acid to increase by feeding ethanol (E-3 and E-5; p>0.05). Conclusion Feeding ethanol directly into drinking water of finishing Hanwoo steers stimulated lipogenesis in intramuscular adipose tissue (marbling) and thereby improved carcass quality grade. The serum metabolites results supported the hypothesis of lipolysis of existing adipose tissue, such as abdominal fats, and lipogenesis in intramuscular adipocytes

    A Novel Magnetic Resonance Quality Assurance Phantom (KMRP-4): Multi-Site Comparison With the American College of Radiology Phantom

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    Purpose: To propose a novel standard magnetic resonance imaging (MRI) phantom, hereafter called the Korea Magnetic Resonance Phantom-4th edition (KMRP-4). Its related quality control (QC) assessment protocols and its comparison with the American College of Radiology (ACR) phantom and its QC assessment protocols. / Materials and Methods: Internally, the KMRP-4 phantom is composed of cubic and triangular vessels, brain tissue structures, and a uniform region designed to facilitate a variety of QC protocols. Using magnetic resonance (MR) images of these structures, we quantitatively evaluated a total of 10 parameters, seven from those of existing ACR protocols (i.e., geometric accuracy, high-contrast spatial resolution, slice thickness accuracy, slice position accuracy, image intensity uniformity, percent signal ghosting, and low-contrast object detectability) and three additional parameters for evaluating vessel conspicuity, brain tissue contrast, and signal-to-noise ratio (SNR) introduced in the KMRP-4 protocols. Twentyt-wo MRI systems of 0.32–3.0 T static magnetic field strength were tested using both ACR and KMRP-4 phantoms. Mann–Whitney U-tests were performed on the seven evaluation items of the ACR method to compare KMRP-4 and ACR methods. / Results: The results of Mann–Whitney U-test demonstrated that p-values were more than 0.05 for all seven items that could be assessed with both ACR and KMRP-4, indicating similar results between the two methods. Additionally, assessments of vessel conspicuity, brain tissue contrast, and SNR using the KMRP-4 method demonstrated utility of the KMRP-4 phantom. / Conclusion: A novel standard phantom and related QC methods were developed to perform objective, observer-independent, and semi-automatic QC tests. Quantitative comparisons of MR images with KMPR-4 and ACR phantoms were performed. Results demonstrated the utility of the newly proposed KMRP-4 phantom and its related QC methods

    The Globular Cluster System of M60 (NGC 4649). I. CFHT MOS Spectroscopy and Database

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    We present the measurement of radial velocities for globular clusters in M60, giant elliptical galaxy in the Virgo cluster. Target globular cluster candidates were selected using the Washington photometry based on the deep 16\arcmin \times 16\arcmin images taken at the KPNO 4m and using the VIVI photometry derived from the HST/WFPC2 archive images. The spectra of the target objects were obtained using the Multi-Object Spectrograph (MOS) at the Canada-France-Hawaii Telescope (CFHT). We have measured the radial velocity for 111 objects in the field of M60: 93 globular clusters (72 blue globular clusters with 1.0≤(C−T1)<1.71.0\le(C-T_1)<1.7 and 21 red globular clusters with 1.7≤(C−T1)<2.41.7\le(C-T_1)<2.4), 11 foreground stars, 6 small galaxies, and the nucleus of M60. The measured velocities of the 93 globular clusters range from ∼500\sim 500 km s−1^{-1} to ∼1600\sim 1600 km s−1^{-1}, with a mean value of 1070−25+271070_{-25}^{+27} km s−1^{-1}, which is in good agreement with the velocity of the nucleus of M60 (vgal=1056v_{\rm gal}=1056 km s−1^{-1}). Combining our results with data in the literature, we present a master catalog of radial velocities for 121 globular clusters in M60. The velocity dispersion of the globular clusters in the master catalog is found to be 234−14+13234_{-14}^{+13} km s−1^{-1} for the entire sample, 223−16+13223_{-16}^{+13} km s−1^{-1} for 83 blue globular clusters, and 258−31+21258_{-31}^{+21} km s−1^{-1} for 38 red globular clusters.Comment: 29 pages, 8 figures. To appear in Ap
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