Kappa-alpha plot derived structural alphabet and BLOSUM-like substitution matrix for rapid search of protein structure database

3D BLAST, a novel protein structure database search tool, is a useful tool for analysing novel structures, capable of returning a list of aligned structures ordered according to E-values

An Integrated Web-based System for MEDLINE Analysis: A Case Study of Chronic Kidney Disease

In the era of big data, medical researchers attempt to utilize some analysis techniques like machine learning and text mining on their large-scale corpora to save valuable labor work and time. Consequently, many data analysis platforms are built to support medical professionals such as Pubtator, GeneWays, BioContext, etc. These platforms are helpful to medical entities recognition and relation extraction, but there is not an integrated platform to support researchers’ various needs, and medical projects are isolated from each other, which is hard to be shared and reused. As a result, we present an integrated system containing ‘name entity recognition’, ‘document categorization’ and ‘association extraction’. Besides, we add the concept of ‘socialization’ making projects reusable for further analyses. A case study of chronic kidney disease was adopted to indicate the effectiveness of the proposed system

Temperature Swing Adsorption Process for CO2 Capture Using Polyaniline Solid Sorbent

AbstractTo capture carbon dioxide from power plant flue gas which consists of 15% CO2 and 85% N2, with a temperature swing adsorption (TSA) by using polyaniline solid sorbent as the adsorbent, is explored experimentally and theoretically. First, single component adsorption equilibrium data of carbon dioxide on polyaniline solid sorbent is obtained by using Micro-Balance Thermo D-200. Then isotherm curves and the parameters are obtained by numerical method. The adsorption is expressed by the Langmuir-Freundlich isotherm. After accomplishment of isotherm curves, the breakthrough curve experiment is investigated with single adsorption column. The experiments test the change in adsorbed gas concentration at the outlet by adsorbed gas, CO2, and non-adsorbed gas, helium. Finally, this study accentuates the TSA experiments on CO2 purity and recovery by operation variable discussion which includes feed pressure, adsorption temperature and desorption temperature to find optimal operation condition. The results of optimal operation condition are CO2 purity of 47.65% with a 92.46% recovery