404 research outputs found

    Intraprofessional Collaboration in Learning Evidence-Based Practice

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    Little is known about how collaborative curricular activities can help students learn about scientific evidence in occupational therapy (OT) and occupational therapy assistant (OTA) programs. We created and measured collaborative learning in evidence-based practice activities to enhance partnership building and intraprofessional collaboration among students in OT and OTA programs. Thirty-three OT students and 26 OTA students enrolled in a didactic course (Phase I) and an intraprofessional collaborative learning activity (Phase II) participated in this quasi-experimental repeated measure study. The students’ ability of how to read scholarly articles and their perceived importance and perceived ability to engage in intraprofessional collaboration were examined at three time points. Improvements were found in the OT students’ perceived importance of intraprofessional roles/responsibilities and the OTA students’ perceived ability to engage in intraprofessional communication after completing the Phase I didactic course. Both the OT and OTA students’ perceived ability to work as a team, identify their roles/responsibilities, communicate with peers, and their ability to read scholarly articles improved after the Phase II intraprofessional collaboration. Students valued the opportunity to gain collaboration experience and share different perspectives. They indicated they would have preferred to spend more time on the activities. The findings suggest that targeted learning activities can improve OT and OTA students’ ability to engage in evidence-based practice and their perceived importance and ability to engage in intraprofessional collaboration. Effective partnerships and intraprofessional collaboration are best introduced within academic programs

    Multiple Imputation Method for High-Dimensional Neuroimaging Data

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    Missingness is a common issue for neuroimaging data, and neglecting it in downstream statistical analysis can introduce bias and lead to misguided inferential conclusions. It is therefore crucial to conduct appropriate statistical methods to address this issue. While multiple imputation is a popular technique for handling missing data, its application to neuroimaging data is hindered by high dimensionality and complex dependence structures of multivariate neuroimaging variables. To tackle this challenge, we propose a novel approach, named High Dimensional Multiple Imputation (HIMA), based on Bayesian models. HIMA develops a new computational strategy for sampling large covariance matrices based on a robustly estimated posterior mode, which drastically enhances computational efficiency and numerical stability. To assess the effectiveness of HIMA, we conducted extensive simulation studies and real-data analysis using neuroimaging data from a Schizophrenia study. HIMA showcases a computational efficiency improvement of over 2000 times when compared to traditional approaches, while also producing imputed datasets with improved precision and stability.Comment: 13 pages, 5 figure

    A statistical reconstruction algorithm for positronium lifetime imaging using time-of-flight positron emission tomography

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    Positron emission tomography (PET) has been widely used for the diagnosis of serious diseases including cancer and Alzheimer's disease, based on the uptake of radiolabelled molecules that target certain pathological signatures. Recently, a novel imaging mode known as positronium lifetime imaging (PLI) has been shown possible with time-of-flight (TOF) PET as well. PLI is also of practical interest because it can provide complementary disease information reflecting conditions of the tissue microenvironment via mechanisms that are independent of tracer uptake. However, for the present practical systems that have a finite TOF resolution, the PLI reconstruction problem has yet to be fully formulated for the development of accurate reconstruction algorithms. This paper addresses this challenge by developing a statistical model for the PLI data and deriving from it a maximum-likelihood algorithm for reconstructing lifetime images alongside the uptake images. By using realistic computer simulation data, we show that the proposed algorithm can produce quantitatively accurate lifetime images.Comment: Submitted to IEEE-TPRM

    High-Pressure Oxidative Leaching and Iodide Leaching Followed by Selective Precipitation for Recovery of Base and Precious Metals from Waste Printed Circuit Boards Ash

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    This paper deals with the recovery of gold from waste printed circuit boards (WPCBs) ash by high-pressure oxidative leaching (HPOL) pre-treatment and iodide leaching followed by reduction precipitation. Base metals present in WPCB ash were removed via HPOL using a diluted sulfuric acid solution at elevated temperatures. Effects of potassium iodide concentration, hydrogen peroxide concentration, sulfuric acid concentration, leaching temperature, and leaching time on gold extraction from pure gold chips with KI-H2O2-H2SO4 were investigated. The applicability of the optimized iodide leaching process for the extraction of gold from the leach residue obtained after HPOL were examined at different pulp densities ranging from 50 g/t to 200 g/t. Results show that the removal efficiency was 99% for Cu, 95.7% for Zn, 91% for Ni, 87.3% for Al, 82% for Co, and 70% for Fe under defined conditions. Under the optimal conditions, the percentage of gold extraction from the gold chips and the residue of WPCBs was 99% and 95%, respectively. About 99% of the gold was selectively precipitated from the pregnant leach solution by sequential precipitation with sodium hydroxide and L-ascorbic acid. Finally, more than 93% of gold recovery was achieved from WPCB ash by overall combined processes

    Future change in extreme precipitation in East Asian spring and Mei-yu seasons in two high-resolution AGCMs

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    Precipitation in the spring and Mei-yu seasons, the main planting and growing period in East Asia, is crucial to water resource management. Changes in spring and Mei-yu extreme precipitation under global warming are evaluated based on two sets of high-resolution simulations with various warming pattern of sea surface temperature (SST'spa). In the spring season, extreme precipitation exhibits larger enhancements over the northern flank of the present-day prevailing rainy region and a tendency of increased occurrence and enhanced intensity in the probability distribution. These changes imply a northward extension of future spring rainband. Although the mean precipitation shows minor change, enhanced precipitation intensity, less total rainfall occurrence, and prolonged consecutive dry days suggest a more challenging water resource management in the warmer climate. The projected enhancement in precipitation intensity is robust compared with the internal variability related to initial conditions (σˆint) and the uncertainty caused by SST'spa (σˆΔSST). In the Mei-yu season, extreme precipitation strengthens and becomes more frequent over the present-day prevailing rainband region. The thermodynamic component of moisture flux predominantly contributes to the changes in the spring season. In the Mei-yu season, both the thermodynamic and dynamic components of moisture flux enhance the moisture transport and intensify the extreme precipitation from southern China to northeast Asia. Compared with spring season, projecting future Mei-yu precipitation is more challenging because of its higher uncertainty associated with 1) the σˆint and σˆΔSST embedded in the projections and 2) the model characteristics of present-day climatology that determines the spatial distribution of precipitation enhancement.publishedVersio

    Effect on Spasticity After Performance of Dynamic-Repeated-Passive Ankle Joint Motion Exercise in Chronic Stroke Patients

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    Spasticity associated with abnormal muscle tone is a common motor disorder following stroke, and the spastic ankle may affect ambulatory function. The purpose of this study was to investigate the short-term effect of dynamic-repeated-passive ankle movements with weight loading on ambulatory function and spastic hypertonia of chronic stroke patients. In this study, 12 chronic stroke patients with ankle spasticity and inefficient ambulatory ability were enrolled. Stretching of the plantar-flexors of the ankle in the standing position for 15 minutes was performed passively by a constant-speed and electrically powered device. The following evaluations were done before and immediately after the dynamic-repeated-passive ankle movements. Spastic hypertonia was assessed by the Modified Ashworth Scale (MAS; range, 0–4), Achilles tendon reflexes test (DTR; range, 0–4), and ankle clonus (range, 0–5). Improvement in ambulatory ability was determined by the timed up-and-go test (TUG), the 10-minute walking test, and cadence (steps/minute). In addition, subjective experience of the influence of ankle spasticity on ambulation was scored by visual analog scale (VAS). Subjective satisfaction with the therapeutic effect of spasticity reduction was evaluated by a five-point questionnaire (1 = very poor, 2 = poor, 3 = acceptable, 4 = good, 5 = very good). By comparison of the results before and after intervention, these 12 chronic stroke patients presented significant reduction in MAS and VAS for ankle spasticity, the time for TUG and 10-minute walking speed (p < 0.01). The cadence also increased significantly (p < 0.05). In addition, subjective satisfaction with the short-term therapeutic effect was mainly good (ranging from acceptable to very good). In conclusion, 15 minutes of dynamic-repeated-passive ankle joint motion exercise with weight loading in the standing position by this simple constant-speed machine is effective in reducing ankle spasticity and improving ambulatory ability

    The Volcanic Earthquake Swarm of October 20, 2009 in the Tatun Area of Northern Taiwan

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    On October 20, 2009, a series of felt earthquakes with local magnitudes ranging from 2.8 - 3.2 occurred in the Tatun volcanic area off the northern tip of Taiwan. Although there was no damage caused by those earthquakes, many residents in the Taipei metropolitan area, particularly for people who live near the Yangminshan National Park, felt strong ground shaking. In order to know what the possible mechanisms were that generated those earthquakes, we carefully examined seismic data recorded by a dense seismic array in the Tatun volcanic area. During the period between October 18 and 22, 2009 we detected at least 202 micro-earthquakes. Most of the earthquakes were relocated using the double-difference method and were clustered in the shallow crust beneath the Dayoukeng area, which is the strongest fumarole in the Tatun volcanic area. Among these earthquakes, 72 focal mechanisms were determined by polarizing the first P-wave motion. Most earthquakes belonged to normal faulting. An extremely high b-value of 2.17 was obtained from those earthquakes. Based on the seismic variations in both the temporary and spatial distribution as well as an extremely high b-value, we conclude that the earthquake sequence on October 20, 2009 was a typically seismic swarm associated with possible active volcanism in the Tatun volcanic area
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