Pigments of the Crinoid Florometra Serretissima

The purpose of the present study is to separate and identify the pigments responsible for the bright orange color of the crinoid Florometra serretissima. This is the first reported investigation of the pigmentation of this particular crinoid

Water quality surveillance: a practical guide

This guide is designed to help staff who undertake surveillance and monitoring of water supplies in developing countries. It provides simple information on how data may be collected and explains the use of equipment and inspection techniques. It also provides example forms that can be easily photocopied, guidance on how monitoring data can be used to improve water supplies and water handling, and how reporting of information can be used to initiate dialogue with communities. The guide was developed with support from the Department for International Development (DFID) (Project no: R6874), and the World Health Organization

Water supply surveillance: a reference manual

This book presents the findings of a research project funded by the Department for International Development (DFID) project no: R6874, and the World Health Organization. It has been written for staff of environmental and public health authorities, water supply agencies and NGOs working in urban areas of developing countries. The project has developed guidelines on the implementation of water supply surveillance based on field experience in Uganda, Ghana and Bangladesh. The guidelines provide a methodology for including poverty and vulnerability into surveillance planning and show how priority groups can be targeted. The book also provides guidance on data collection and use of surveillance findings in improving water supplies and water handling practices as a way of reducing public health risks derived from poor water supply. It emphasises the need for partnerships with communities and identifies the way in which information can be shared and used by a range of organisations

Strategic approaches to urban sanitation

Strategic approaches to urban sanitatio

The Cerebellum and SIDS: Disordered Breathing in a Mouse Model of Developmental Cerebellar Purkinje Cell Loss during Recovery from Hypercarbia.

The cerebellum assists coordination of somatomotor, respiratory, and autonomic actions. Purkinje cell alterations or loss appear in sudden infant death and sudden death in epilepsy victims, possibly contributing to the fatal event. We evaluated breathing patterns in 12 wild-type (WT) and Lurcher mutant mice with 100% developmental cerebellar Purkinje cell loss under baseline (room air), and recovery from hypercapnia, a concern in sudden death events. Six mutant and six WT mice were exposed to 4-min blocks of increasing CO2 (2, 4, 6, and 8%), separated by 4-min recovery intervals in room air. Breath-by-breath patterns, including depth of breathing and end-expiratory pause (EEP) durations during recovery, were recorded. No baseline genotypic differences emerged. However, during recovery, EEP durations significantly lengthened in mutants, compared to WT mice, following the relatively low levels of CO2 exposure. Additionally, mutant mice exhibited signs of post-sigh disordered breathing during recovery following each exposure. Developmental cerebellar Purkinje cell loss significantly affects compensatory breathing patterns following mild CO2 exposure, possibly by inhibiting recovery from elevated CO2. These data implicate cerebellar Purkinje cells in the ability to recover from hypercarbia, suggesting that neuropathologic changes or loss of these cells contribute to inadequate ventilatory recovery to increased environmental CO2. Multiple disorders, including sudden infant death syndrome (SIDS) and sudden unexpected death in epilepsy (SUDEP), appear to involve both cardiorespiratory failure and loss or injury to cerebellar Purkinje cells; the findings support the concept that such neuropathology may precede and exert a prominent role in these fatal events

Water safety plans - Book 2: Supporting water safety management for urban piped water supplies in developing countries

Historically, global control of drinking water has relied upon infrequent testing of selected water quality parameters at specified points within a water supply. Weaknesses identified by the World Health Organization (WHO) in this approach have resulted in a fundamental change noted in the revised, third edition of the WHO Guidelines for Drinking Water Quality, 2004. The change involves the development of quality assurance processes known as Water Safety Plans (WSPs) founded upon the HACCP principles used in the food industry. Water Safety Plans - Books 1 and 2, document state of the art research designed to complement the advances being made in the global water quality sector. Book 1 presents guidelines for implementing WSPs in developing countries. Book 2 gives further detail on supporting programmes. Together they provide essential reading for water utility managers, helping them to assess, identify and manage water quality risk in their piped water supplies, as well as individuals and organizations representing vulnerable groups and suggesting methods for improving monitoring and management of water quality in low socio-economic areas. Evidence for these books is drawn from three years of research undertaken in Uganda and India funded by the Department for International Development (DFID)

Water safety plans - Book 1: Planning water safety management for urban piped water supplies in developing countries

Historically, global control of drinking water has relied upon infrequent testing of selected water quality parameters at specified points within a water supply. Weaknesses identified by the World Health Organization (WHO) in this approach have resulted in a fundamental change noted in the revised, third edition of the WHO Guidelines for Drinking Water Quality, 2004. The change involves the development of quality assurance processes known as Water Safety Plans (WSPs) founded upon the HACCP principles used in the food industry. Water Safety Plans - Books 1 and 2, document state of the art research designed to complement the advances being made in the global water quality sector. Book 1 presents guidelines for implementing WSPs in developing countries. Book 2 gives further detail on supporting programmes. Together they provide essential reading for water utility managers, helping them to assess, identify and manage water quality risk in their piped water supplies, as well as individuals and organizations representing vulnerable groups and suggesting methods for improving monitoring and management of water quality in low socio-economic areas. Evidence for these books is drawn from three years of research undertaken in Uganda and India funded by the Department for International Development (DFID)

User Disengagement And The Turnaround Of A Failing Project

This paper reports on an in-depth case study of a large and strategic IT development project facing business user disengagement and potential system rejection. Somewhat belatedly senior management recognised the threat and appointed a new project manager with a brief to rescue the project whilst keeping to the original implementation deadline. Much to almost everyone\u27s surprise the new project manager, and his radical approach, produced the required significant results. The paper examines the changes instigated by the new project manager and a group of newly appointed Business Analysts (BAs). The approach, based on participation ideas, utilized an adapted state modelling technique, and was framed within the agile informed management approach, succeeded in achieving an emergence of business users’ belief and the feeling that they could not just influence the system but design it in a way that was needed by the business and that would support the current required workflows as well as for the future, which was somewhat uncertain. The detail of the approach is described and the way in which the disengagement and turnaround was achieved is provided. The paper concludes by outlining the contributions of the case and the approach and suggesting a relevance not only to the systems development and participation literature but potentially to the concept of systems ownership and Psychological Ownership (PO) which it could be argued were invoked in the case