Intraneuronal information processing, directional selectivity and memory for spatio-temporal sequences.

Interacting intracellular signalling pathways can perform computations on a scale that is slower, but more fine-grained, than the interactions between neurons upon which we normally build our computational models of the brain (Bray D 1995 Nature 376 307-12). What computations might these potentially powerful intraneuronal mechanisms be performing? The answer suggested here is: storage of spatio-temporal trajectories; thus, neurons have some of the capacities required to perform such a task. In the retina, it is suggested that calcium-induced calcium release (CICR) may provide the basis for directional selectivity. In the cortex, if activation mechanisms with different delays could be separately reinforced at individual synapses then each such Hebbian super-synapse would store a memory trace of the delay between pre- and post-synaptic activity, forming an ideal basis for the memory and response to phase sequences

Criminal Minded? : Mixtape DJs, The Piracy Paradox, and Lessons for the Recording Industry

For at least the past three years, leading American fashion designers have lobbied for passage of copyright-like protection for the design aspects of their apparel creations. For at least as long, the recorded music industry has been engaged in an aggressive campaign to enforce its copyrights in recorded music against a number of technology-enabled and/or culturally sympathetic alleged infringers, including twelve year-olds and grandmothers. Although the record labels already have protection under the copyright law while the fashion houses seek it, they have at least one thing in common: some portion of the piracy that they seek to eradicate is more valuable to them than they publicly let on. In their recent article The Piracy Paradox: Innovation and Intellectual Property in Fashion Design, Kal Raustiala and Chris Sprigman explore the low-IP equilibrium of the fashion design industry, as well as the unexpected value created by a low-protection regime. One might ask whether there is anything wrong with chilling an unlawful activity such as large-scale copyright infringement. The article argues that there is something wrong with such a result, but that the owners of the copyright in the recordings either fail to appreciate the problem or fail to account for the problem in executing their enforcement strategy. Hip-hop mixtape DJs are engaged in productive infringement – infringing activity or improper appropriation that adds value to the infringed asset, rather than leading to losses for the copyright owner. Dealing with such infringement requires an approach different from typical recording industry tactics. This article argues that, in order to preserve and enhance the value of their own assets, the record labels should practice strategic forbearance