1 research outputs found
Selective Deprotection Method of <i>N</i>‑Phenylcarbamoyl Group
We report an improved method for
the selective deprotection of
the <i>N</i>-phenylcarbamoyl group, which yields the corresponding
alcohol without affecting other protecting groups. Deprotection was
performed using di-<i>tert</i>-butyl dicarbonate and tetra-<i>n</i>-butylammonium nitrite (Boc<sub>2</sub>O and Bu<sub>4</sub>NNO<sub>2</sub>) in pyridine at room temperature. This method is
also effective for deprotecting the fluorous <i>N</i>-phenylcarbamoyl
group