450 research outputs found
Fifth Year Persisters: High School, College, and Early Career Outcomes For Persisting Non-Graduates
There is limited extant knowledge regarding academic and workforce experiences of students who remain engaged in high school, but do not graduate in the traditional four years. The current study used Multilevel modeling and descriptive statistics with statewide linked longitudinal administrative data (N = 2917) to (1) examine the student- and school-level factors related to earning a diploma during the fifth year of high school and (2) describe proximate academic and career outcomes for non-graduates and fifth year graduates. Multiple student-level factors were associated with increased likelihood of earning a diploma in the fifth year (e.g. special education eligibility, passing exit exams, higher attendance). Returning dropouts were less likely than persisters to earn a diploma in year five. In addition, the type and composition of the school a student attended affected the likelihood that a student would earn a diploma in year five. We also report population-level rates of participation in the workforce and postsecondary enrollment for fifth-year graduates and non-graduates. Fifth-year graduates outperformed non-graduates in both categories. Our findings provide insight into near term outcomes for students in a fifth-year of high school and suggest key factors that can be used for early identification and targeting services towards this under-researched and under-served population
Poynting's theorem and energy conservation in the propagation of light in bounded media
Starting from the Maxwell-Lorentz equations, Poynting's theorem is
reconsidered. The energy flux vector is introduced as S_e=(E x B)/mu_0 instead
of E x H, because only by this choice the energy dissipation can be related to
the balance of the kinetic energy of the matter subsystem. Conservation of the
total energy as the sum of kinetic and electromagnetic energy follows. In our
discussion, media and their microscopic nature are represented exactly by their
susceptibility functions, which do not necessarily have to be known. On this
footing, it can be shown that energy conservation in the propagation of light
through bounded media is ensured by Maxwell's boundary conditions alone, even
for some frequently used approximations. This is demonstrated for approaches
using additional boundary conditions and the dielectric approximation in
detail, the latter of which suspected to violate energy conservation for
decades.Comment: 5 pages, RevTeX4, changes: complete rewrit
Analog modulation of mossy fiber transmission is uncoupled from changes in presynaptic Ca2+
Subthreshold somatic depolarization has been shown recently to modulate presynaptic neurotransmitter release in cortical neurons. To understand the mechanisms underlying this mode of signaling in the axons of dentate granule cells (hippocampal mossy fibers), we have combined two- photon Ca2+ imaging with dual-patch recordings from somata and giant boutons forming synapses on CA3 pyramidal cells. In intact axons, subthreshold depolarization propagates both orthodromically and antidromically, with an estimated length constant of 200-600 mu m depending on the signal waveform. Surprisingly, presynaptic depolarization sufficient to enhance glutamate release at mossy fiber-CA3 pyramidal cell synapses has no detectable effect on either basal Ca2+-dependent fluorescence or action-potential-evoked fluorescence transients in giant boutons. We further estimate that neurotransmitter release varies with presynaptic Ca2+ entry with a 2.5-power relationship and that depolarization-induced synaptic facilitation remains intact in the presence of high-affinity presynaptic Ca2+ buffers or after blockade of local Ca2+ stores. We conclude that depolarization-dependent modulation of transmission at these boutons does not rely on changes in presynaptic Ca2+
Persistent Current of Free Electrons in the Plane
Predictions of Akkermans et al. are essentially changed when the Krein
spectral displacement operator is regularized by means of zeta function.
Instead of piecewise constant persistent current of free electrons on the plane
one has a current which varies linearly with the flux and is antisymmetric with
regard to all time preserving values of including . Different
self-adjoint extensions of the problem and role of the resonance are discussed.Comment: (Comment on "Relation between Persistent Currents and the Scattering
Matrix", Phys. Rev. Lett. {\bf 66}, 76 (1991)) plain latex, 4pp., IPNO/TH
94-2
Impact of heavy hole-light hole coupling on optical selection rules in GaAs quantum dots
We report strong heavy hole-light mixing in GaAs quantum dots grown by
droplet epitaxy. Using the neutral and charged exciton emission as a monitor we
observe the direct consequence of quantum dot symmetry reduction in this strain
free system. By fitting the polar diagram of the emission with simple
analytical expressions obtained from kp theory we are able to extract
the mixing that arises from the heavy-light hole coupling due to the
geometrical asymmetry of the quantum dot.Comment: 4 pages, 2 figure
Dopamine elevates and lowers astroglial Ca(2+) through distinct pathways depending on local synaptic circuitry
Whilst astrocytes in culture invariably respond to dopamine with cytosolic Ca(2+) rises, the dopamine sensitivity of astroglia in situ and its physiological roles remain unknown. To minimize effects of experimental manipulations on astroglial physiology, here we monitored Ca(2+) in cells connected via gap junctions to astrocytes loaded whole-cell with cytosolic indicators in area CA1 of acute hippocampal slices. Aiming at high sensitivity of [Ca(2+) ] measurements, we also employed life-time imaging of the Ca(2+) indicator Oregon Green BAPTA-1. We found that dopamine triggered a dose-dependent, bidirectional Ca(2+) response in stratum radiatum astroglia, a jagged elevation accompanied and followed by below-baseline decreases. The elevation depended on D1/D2 receptors and engaged intracellular Ca(2+) storage and removal whereas the dopamine-induced [Ca(2+) ] decrease involved D2 receptors only and was sensitive to Ca(2+) channel blockade. In contrast, the stratum lacunosum moleculare astroglia generated higher-threshold dopamine-induced Ca(2+) responses which did not depend on dopamine receptors and were uncoupled from the prominent inhibitory action of dopamine on local perforant path synapses. Our findings thus suggest that a single neurotransmitter-dopamine-could either elevate or decrease astrocyte [Ca(2+) ] depending on the receptors involved, that such actions are specific to the regional neural circuitry and that they may be causally uncoupled from dopamine actions on local synapses. The results also indicate that [Ca(2+) ] elevations commonly detected in astroglia can represent the variety of distinct mechanisms acting on the microscopic scale. GLIA 2016
Altered balance of glutamatergic/GABAergic synaptic input and associated changes in dendrite morphology after BDNF expression in BDNF-deficient hippocampal neurons
Cultured neurons from bdnf-/- mice display reduced densities of synaptic terminals, although in vivo these deficits are small or absent. Here we aimed at clarifying the local responses to postsynaptic brain-derived neurotrophic factor (BDNF). To this end, solitary enhanced green fluorescent protein (EGFP)-labeled hippocampal neurons from bdnf-/- mice were compared with bdnf-/- neurons after transfection with BDNF, bdnf-/- neurons after transient exposure to exogenous BDNF, and bdnf+/+ neurons in wild-type cultures. Synapse development was evaluated on the basis of presynaptic immunofluorescence and whole-cell patch-clamp recording of miniature postsynaptic currents. It was found that neurons expressing BDNF::EGFP for at least 16 h attracted a larger number of synaptic terminals than BDNF-deficient control neurons. Transfected BDNF formed clusters in the vicinity of glutamatergic terminals and produced a stronger upregulation of synaptic terminal numbers than high levels of ambient BDNF. Glutamatergic and GABAergic synapses reacted differently to postsynaptic BDNF: glutamatergic input increased, whereas GABAergic input decreased. BDNF::EGFP-expressing neurons also differed from BDNF-deficient neurons in their dendrite morphology: they exhibited weaker dendrite elongation and stronger dendrite initiation. The upregulation of glutamatergic synaptic input and the BDNF-induced downregulation of GABAergic synaptic terminal numbers by postsynaptic BDNF depended on tyrosine receptor kinase B activity, as deduced from the blocking effects of K252a. The suppression of dendrite elongation was also prevented by block of tyrosine receptor kinase B but required, in addition, glutamate receptor activity. Dendritic length decreased with the number of glutamatergic contacts. These results illuminate the role of BDNF as a retrograde synaptic regulator of synapse development and the dependence of dendrite elongation on glutamatergic input
ОБРАБОТКА ДАННЫХ ДЛЯ СОСТАВЛЕНИЯ ТЕХНОЛОГИЧЕСКОГО БАЛАНСА
Теоретично доведено, що для отримання несуперечливих результатів обчислення виходу
продукту необхідно використовувати кореляційні функції, які входять до обчислювальної
формули.Теоретично доведено, що для отримання несуперечливих результатів обчислення виходу
продукту необхідно використовувати кореляційні функції, які входять до обчислювальної
формули
Optical Properties of Crystals with Spatial Dispersion: Josephson Plasma Resonance in Layered Superconductors
We derive the transmission coefficient, , for grazing incidence of
crystals with spatial dispersion accounting for the excitation of multiple
modes with different wave vectors for a given frequency . The
generalization of the Fresnel formulas contains the refraction indices of these
modes as determined by the dielectric function . Near
frequencies , where the group velocity vanishes, depends
also on an additional parameter determined by the crystal microstructure. The
transmission is significantly suppressed, if one of the excited modes is
decaying into the crystal. We derive these features microscopically for the
Josephson plasma resonance in layered superconductors.Comment: 4 pages, 2 figures, epl.cls style file, minor change
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