The association between fever and pyuria in children older than one month

Introduction: Some assumptions have been made on the probable association between fever and pyuria. Objectives: The present study aimed to investigate the association between fever and pyuria. Patients and Methods: In this case-control study, 90 febrile and 90 non-febrile children aged more than one month who were admitted to the pediatric ward were included. Urine specimens of children less than 2 years of age were collected by urine bag. Midstream urine samples were collected and immediately sent to the laboratory for complete urinalysis and urine culture. Results: Overall, 6.7% in febrile children and 2.2% in control group had pyuria however there was no significant association between fever and pyuria (P>0.05). Additionally, no association between the presence of pyuria and type of disease was detected (P>0.40). Conclusion: The present study could not reveal any association between fever and pyuria in children older than one month. Keywords: Pyuria, Interstitial nephritis, Feve

The Effectiveness of Life Skills Training on Quality of Life in Mothers of Children with Down Syndrome

Objectives:  This  study  aimed  to  examine  the  effectiveness  of  life  skills  training  on  quality  of  life  in mothers of children with Down syndrome.  Methods:  This  research  was  done  as  a  semi-experimental  with  pre-post  test  and  with  control  group. Statistical population included all children with down syndrome, age from 2 months to 8 years, and their mothers who referred to Iran's down syndrome society. Thirty six children were randomly chosen and equally assigned to two groups: experimental and control group. The data were collected by using the demographic  questionnaire  and  the  short  form  of  the  World  Health  Organization  Quality  of  Life. Experimental group was trained for life skills in 12 sessions, each session 60 minutes. Data were analyzed using SPSS-16 software and multivariate analysis of covariance test.   Results:  The  results  indicate  that  the  mean  score  of  quality  of  life  in  the  experimental  group  was significantly higher than the control group after intervention.  Discussion: According to the results, life skills training increased the quality of life in mothers of children with  Down  syndrome. Therefore  the  life  skill  training  can  be  applied  in  mental  health  services  for improving the quality of life in mothers of children with Down syndrome. &nbsp

Serotonin Transporter Polymorphism (5-HTTLPR) and Citalopram Effectiveness in Iranian Patients with Major Depressive Disorder

Objective:Several studies have implicated the 5-HTTLPR polymorphism in treatment outcomes of selective serotonin re-uptake inhibitors in patients with major depression. The aim of this study was to examine the association between polymorphism in the serotonin transporter gene and citalopram effectiveness in Iranian patients suffering from major depressive disorder (MDD).Methods:The sample consisted of 104 patients, with Fars ethnic background, who were diagnosed according to DSM-IV-TR criteria. Beck Depression inventory was used to evaluate the severity of the symptoms during the follow-up, and to determine clinical response of the patients at 4th and 8th week, respectively.Results:Our results showed a correlation between the genotype and response to antidepressant drug citalopram, (odds ratios for L/S and L/L were 3.90 (95 percent CI: 1.29- 11.80) and 1.90 (95 percent CI: 0.72-5.08), respectively).Conclusion:In conclusion, our results reveal that genetic variation of serotonin transporter is involved in clinical remission of major depressive episodes in Iranian patients after citalopram treatment