The Changing Landscape for Stroke\ua0Prevention in AF: Findings From the GLORIA-AF Registry Phase 2

Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non\u2013vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase 1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients\u2019 baseline characteristics. Atrial fibrillation disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age  6575 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score  652; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc = 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N = 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in Asia and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701

Exploring cetacean stranding pattern in light of variation in at-sea encounter rate and fishing activity : lessons from time surveys in the south Bay of Biscay (East-Atlantic; France)

International audienceTo date, the scarcity of year-round and long-term programmes integrating multi-dimensional data has hindered the development of a good understanding of cetacean mortality worldwide. This study uses data from: 1) standardised shipboard surveys (1980-2002), 2) standardised stranding surveys (1980-2002) and 3) landings of fishing fleets (2000-2002) in the Bay of Biscay. It investigates the correlations between stranding, at-sea encounter rate and the fishing index for three common cetaceans: common dolphin (Delphinus delphis), bottlenose dolphin (Tursiops truncatus) and long-finned pilot whale (Globicephala melas). At the monthly scale, a seasonal stranding pattern significantly congruent with the at-sea encounter rate and the fishing index for D. delphis is revealed. At the inter-annual scale, stranding and at-sea encounter rates are shown to be correlated (p = 0.013-0.044 according to species) and significantly increasing in abundance. Temporal variation in the ratio between individuals seen alive at sea and those stranded shows no significant trend suggesting that stranding is better explained by at-sea abundance than by the fishing index. Managers can use these findings to re-evaluate the relative contribution of by-catch fisheries in the context of observed changes of at-sea cetacean abundance and the link to oceano-climatic changes and other anthropogenic causes

Oiseaux marins et cétacés du golfe de Gascogne

Cet ouvrage Oiseaux marins et cétacés du golfe de Gascogne présente l’évolution numérique et la répartition géographique des 36 espèces d’oiseaux marins ainsi que des 3 espèces de cétacés communs dans les eaux du golfe de Gascogne sur les 30 dernières années. En plus des monographies complètes de chaque espèce, le lecteur y trouve une analyse croisée de leurs cycles biologiques (migration, hivernage, reproduction...) en fonction des milieux naturels et des secteurs du golfe. De belles photographies en couleur viennent illustrer le propos. L’ouvrage détaille enfin les facteurs clés de l’évolution des populations comme la pollution d’origine humaine ou les variations océano-climatiques. L’apport du suivi en mer : Les données de l’ouvrage s’appuient sur plus de 2200 heures d’observation en mer à partir des vedettes des douanes françaises ou des Affaires maritimes. Avec une zone d’étude allant de la frange littorale à plus de 120 km au large.</p

Fractionnement par voie sèche du son de blé pour la production d’ingrédients alimentaires

National audienc

Bilan et optimisation de l’énergie de fractionnement par voie sèche des grains de céréales

Bilan et optimisation de l’énergie de fractionnement par voie sèche des grains de céréales. 60. Journées Techniques des Industries Céréalières (JTIC

Fractionnement par voie sèche des sons de blé pour la production d’ingrédients alimentaires.

National audienc

Rapport du groupe de travail sur les oiseaux marins: bilans et propositions de recherches

CNRS RP 185 (2033) / INIST-CNRS - Institut de l'Information Scientifique et TechniqueSIGLEFRFranc

L'AGE D'OR DE LA CHANSON GRIVOISE

Collection : L'Âge d'or du Music-HallCollection : L'Âge d'or du Music-HallComprend : LE RENDEZ-VOUS D'ELISE / SPENCER et BERETTO - AVEC MON ECOSSAISE / CHRISTINE et RIMBAULT ; URBAN - LE CHAPEAU DE LA MARGUERITE / BLAQUIERE et HEMERY ; Charlotte CLASIS - LES TRIBULATIONS D'UN PIPELET / FONTENELLE - RAITER et BRIOLLET ; CHARLUS - MIMI FAIS-MOI DANSER / OUVRARD et DUFLEUVE ; Alfred DUFLEUVE - A CAUSE DU BILBOQUET / Vincent SCOTTO - HERMITE - LEMARCHAND et Géo KOGER ; Mireille PONSARD - OUVR' LA FENETRE / PREVOST - PENDANT LA PAVANE / ALIX - ON VIENT D'ME L'FAIRE / SOLER et GRACEY - CA PEUT S'DIRE / NIKELMANN et GRACEY ; SANDREY - LE BOUC A N ? NON / MATIS - RIEUX - MERRY - LE JOLI FUSIL / BOSSUYT de LYLLE et GUMERY ; Berthe SYLVABnF-Partenariats, Collection sonore - BelieveContient une table des matière