Sweetclover Weevil

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Dynamical Stability of Witten Rings

The dynamical stability of cosmic rings, or vortons, is investigated for the particular equation of state given by the Witten bosonic model. It is found that there exists a finite range of the state parameter for which the vorton states are actually stable against dynamical perturbations. Inclusion of the electromagnetic self action into the equation of state slightly shrinks the stability region but otherwise yields no qualitative difference. If the Witten bosonic model represents a good approximation for more realistic string models, then the cosmological vorton excess problem can only be solved by assuming either that strings are formed at low energy scales or that some quantum instability may develop at a sufficient rate.Comment: 11 pages, LaTeX-ReVTeX (v.3), 2 figures available upon request, DAMTP R-94/1

S1×S2S^1 \times S^2 wormholes and topological charge

I investigate solutions to the Euclidean Einstein-matter field equations with topology $S^1 \times S^2 \times R$ in a theory with a massless periodic scalar field and electromagnetism. These solutions carry winding number of the periodic scalar as well as magnetic flux. They induce violations of a quasi-topological conservation law which conserves the product of magnetic flux and winding number on the background spacetime. I extend these solutions to a model with stable loops of superconducting cosmic string, and interpret them as contributing to the decay of such loops.Comment: 18 pages (includes 6 figs.), harvmac and epsf, CU-TP-62

Oscillation damping of chiral string loops

Chiral cosmic string loop tends to the stationary (vorton) configuration due to the energy loss into the gravitational and electromagnetic radiation. We describe the asymptotic behaviour of near stationary chiral loops and their fading to vortons. General limits on the gravitational and electromagnetic energy losses by near stationary chiral loops are found. For these loops we estimate the oscillation damping time. We present solvable examples of gravitational radiation energy loss by some chiral loop configurations. The analytical dependence of string energy with time is found in the case of the chiral ring with small amplitude radial oscillations.Comment: 10 pages, 2 figures. Accepted for publication in Physical Review

Interaction between vortices in models with two order parameters

The interaction energy and force between widely separated strings is analyzed in a field theory having applications to superconducting cosmic strings, the SO(5) model of high-temperature superconductivity, and solitons in nonlinear optics. The field theory has two order parameters, one of which is broken in the vacuum (giving rise to strings), the other of which is unbroken in the vacuum but which could nonetheless be broken in the core of the string. If this does occur, there is an effect on the energetics of widely separated strings. This effect is important if the length scale of this second order parameter is longer than that of the other fields in the problem.Comment: 11 pages, 3 figures. Minor changes in the text. Accepted for publication in Phys. Rev.

Phases of dual superconductivity and confinement in softly broken N=2 supersymmetric Yang-Mills theories

We study the electric flux tubes that undertake color confinement in N=2 supersymmetric Yang-Mills theories softly broken down to N=1 by perturbing with the first two Casimir operators. The relevant Abelian Higgs model is not the standard one due to the presence of an off-diagonal coupling among different magnetic U(1) factors. We perform a preliminary study of this model at a qualitative level. BPS vortices are explicitely obtained for particular values of the soft breaking parameters. Generically however, even in the ultrastrong scaling limit, vortices are not critical but live in a "hybrid" type II phase. Also, ratios among string tensions are seen to follow no simple pattern. We examine the situation at the half Higgsed vacua and find evidence for solutions with the behaviour of superconducting strings. In some cases they are solutions to BPS equations.Comment: 15 pages, 1 figure, revtex; v2: typos corrected, final versio

Advancing newborn health: The Saving Newborn Lives initiative

Until recently, newborn health was virtually absent from the global health agenda. Now, assistance agencies, national governments and non-governmental organisations are increasingly addressing this previously neglected issue of close to four million newborns dying every year. The experience of the Saving Newborn Lives initiative documents some of the progress that has been made and the challenges and opportunities that lie ahead. Since the start of the initiative in 2000, targeted research, focused on overcoming the key barriers to improved newborn survival, has demonstrated low-cost, community-based interventions and strategies that can significantly reduce newborn mortality. Building on what has been learned from this and other efforts to date, the challenge now is to reach the millions of newborns still at risk

PathogenMip Assay: A Multiplex Pathogen Detection Assay

The Molecular Inversion Probe (MIP) assay has been previously applied to a large-scale human SNP detection. Here we describe the PathogenMip Assay, a complete protocol for probe production and applied approaches to pathogen detection. We have demonstrated the utility of this assay with an initial set of 24 probes targeting the most clinically relevant HPV genotypes associated with cervical cancer progression. Probe construction was based on a novel, cost-effective, ligase-based protocol. The assay was validated by performing pyrosequencing and Microarray chip detection in parallel experiments. HPV plasmids were used to validate sensitivity and selectivity of the assay. In addition, 20 genomic DNA extracts from primary tumors were genotyped with the PathogenMip Assay results and were in 100% agreement with conventional sequencing using an L1-based HPV genotyping protocol. The PathogenMip Assay is a widely accessible protocol for producing and using highly discriminating probes, with experimentally validated results in pathogen genotyping, which could potentially be applied to the detection and characterization of any microbe