The Relationship between the Results of Coagulation Profile and Severity of Pulmonary Involvement in COVID-19 Patients

Introduction: COVID-19 is currently a global pandemic, and coagulation-related mortality has been widely reported in patients suffering from it. Objective: this article aimed to investigate the coagulation profile of COVID-19 patients. Methods: This was a cross-sectional study conducted using a retrospective research design. We recruited patients with COVID-19 admitted to a hospital from June 15th to July 7th, 2020. Upon patients' entering a blood sample was drawn from each patient for assessing patient’s coagulation profile (PT, PTT, INR, Platelet count); and a chest high-resolution computed tomography (HRCT) scan was performed for each patient. The study patients were divided in to sever group (CO-RADS score 5) and non-sever group (CO-RADS score <5). Results: Thirty-six patients (20 males and 16 females) with a mean age of 54.7±17.5 years were studied. Of them, 11 cases (30.56%) had severe pulmonary involvement. Also, the coagulation profiles were longer in the severe group than non-sever group. As well, the means of platelet count that were 232.440 per microliter in the non-severe group and 289.180 per microliter in the severe and non-sever groups, respectively; but still not statistically significant (p>0.05). The Area under the ROC Curve (AUC) for PT and INR was 0.615 and 0.611, respectively. The AUC for platelet count was 0.680 (95% CI: 0.501 to 0.859) and had an acceptable discriminating power. Conclusions: In this study, we did not find any statistically significant relationship between the results of coagulation tests and the severity of pulmonary involvement according to HRCT scan findings in COVID-19 patients. But further analyses suggest that, except PTT, the other coagulation tests (PT, INR, and platelet count) may discriminate severe COVID-19 patients

Gender Differences in COVID-19 Deceased Cases in Jahrom City, South of Iran

Objective: To evaluate the clinical and epidemiological features of deceased patients and comparing the discrepancies between male and female patients based on high prevalence of coronavirus disease 2019 (COVID-19), its irreversible effects and the rising mortality rate in Jahrom city. Methods: This is a descriptive-analytical retrospective study that was conducted from the beginning of March 2020 to the end of November 2020. The study population were included all patients with COVID-19 who admitted to Peymaniyeh Hospital in Jahrom and died of COVID-19. Clinical and demographic data were collected from medical records and analyzed by SPSS software. Results: In this study, 61 patients (57.54%) were men and 45 patients (42.36%) were women. The mean age was 68.7±18.33 in men and 68.82±14.24 in women. The mean hospitalization length was 9.69±7.75 days in men and 9.69±7.75 days in women patients. There was no statistically significant difference between men and women patients (p>0.05). The results showed that 17 (27.87%) men and 28 (45.9%) of women patients had hypertension and the prevalence of this disease was significantly higher in women than men (p=0.01). In this study, 7 (11.48%) men and 13 (21.31%) women had hyperlipidemia. The frequency of hyperlipidemia in women caseswas significantly higher than in men patients (p=0.024). Men cases’ diastolic blood pressure (mean=77.53) was significantly higher than women’s diastolic blood pressure at the same time with a mean of 71.42 (p <0.05). Conclusion: The findings of the study represented the mortality rate in men which is higher than women patients. The prevalence of underlying diseases such as hypertension and hyperlipidemia were higher in women than men. Despite higher mortality among women, symptoms such as fever and dyspnea were less common in women than men

Case Report: A case study of abdominal aortic aneurysm in a bladder cancer patient

Abstract: Introduction: Abdominal aortic aneurysm (AAA) is a local dilation of the abdominal aorta that increases the risk of rupture up to 50% of normal diameter. AAA is the leading cause of death and is the 13th leading cause of death in the United States. Aging, male gender and smoking are the most important causes of AAA. At present, there is no drug treatment to prevent the development of AAA and mortality after rupture remains high. Case Report: The patient was a 74-year-old man with hypertension, hyperlipidemia, lumbar disc, lower extremity paralysis, chronic heart disease and bladder cancer. He underwent 2 operations due to cancer with abdominal pain and a history of fainting in the previous hour at home. Is. Conclusion: In elderly patients with abdominal pain with or without underlying disease, according to the symptoms and clinical examinations, the patient can be examined for abdominal aortic aneurysm and thus there will be more time to treat the patient

پریشانی اخلاقی و مولفه های مرتبط با آن در پرسنل بخش اورژانس؛ یک مطالعه مروری

Introduction: Moral distress is one of the hidden moral challenges in providing nursing care services that occurs in conditions of impossibility to perform the right job despite knowing its correctness. This challenge is greater among nurses in wards with more acute conditions, such as the emergency department. This study was conducted with the aim of systematically reviewing moral distress and its related components in studies conducted on emergency department employees. Methods: This research is based on a systematic review that evaluates the quality of articles using the STROBE standard checklist. Preliminary studies were conducted through articles in Persian language databases; SID, Iranmedex, Magiran and English language databases; Science Direct, PubMed, ProQuest, Cochrane Library, Embase, Scopus and Google Scholar; was examined. In order to access the full text of articles containing Persian keywords; Moral distress, moral stress, moral stress, moral distress, moral anxiety, moral turmoil, and emergency-related phrases were used as a combination of words; Also includes boolean search methods and OR operators and Mesh keywords; Moral Distress, Ethical Distress, Ethical unease, Ethical disquiet, Emergency were used. Results: In the initial stage, 466 studies were studied. The researchers then reviewed the articles that had been searched, and finally, after removing duplicate, irrelevant items, qualitative studies, narrative review, and a letter to the editor; 18 researches were used to write this research. Among the studies studied, 11 Iranian articles were conducted, which shows 61.11% of the total studies; other studies have been conducted in Taiwan, China, the United States, Indonesia and Switzerland. The average moral distress of emergency department nurses was moderate and there was a significant relationship with components such as background and workload of the findings of these studies. Conclusion: The set of studies performed on emergency department nurses is a reliable number to show the level of moral distress, but this amount of study is not reliable to obtain a model of components and variables related to moral distress. For this purpose, in addition to further research on this group of nurses, by removing the characteristics of emergency department nurses, a systematic review of all studies conducted in the field of moral distress on the nursing community can be done to achieve more accurate results.مقدمه: پریشانی اخلاقی یکی چالش های اخلاقی پنهان در حین ارائه خدمات مراقبتی پرستاران است که در شرایط عدم امکان اجرای کار درست علیرغم آگاهی از درستی آن پیش می آید. این چالش در بین پرستاران بخش هایی که شرایط حاد تری دارند نظیر بخش اورژانس بیشتر است. این تحقیق، با هدف مرور نظام مند پیرامون پریشانی اخلاقی و مولفه های مرتبط با آن در مطالعات انجام شده بر روی پرسنل بخش اورژانس، صورت گرفت. روش کار: این پژوهش مبتنی بر یک مرور نظام‌مند می باشد که ارزیابی کیفیت مقاله ها با استفاده از چک لیست استاندارد STROBE، صورت گرفت. مطالعات اولیۀ انجام شده، از طریق مقاله هایی که در پایگاه‌های اطلاعاتی فارسی زبان؛SID ،Iranmedex،Magiran و پایگاه های انگلیسی زبان؛ Science Direct، PubMed، ProQuest،Cochrane Library،Embase،Scopus و موتور جستجوگر Google Scholar؛ مورد بررسی قرار گرفت. به منظور دستیابی به متن کامل مقاله هایی که از کلید واژه های فارسی؛ پریشانی اخلاقی، تنیدگی اخلاقی، تنش اخلاقی، دیسترس اخلاقی، اضطراب اخلاقی، آشفتگی اخلاقی و عبارات مرتبط با اورژانس به صورت ترکیب واژگان استفاده گردید؛ همچنین از روش های جستجوی بولین و عملگرهای And و OR و کلید واژه های MeSH &nbsp;شامل؛&nbsp; Moral Distress, Ethical Distress, Ethical unease, Ethical disquiet, Emergency &nbsp;استفاده&nbsp; شد. یافته ها: در مرحلۀ اولیه، 466 تحقیق مورد مطالعه و بررسی قرار گرفت. سپس پژوهشگران به بررسی مقاله هایی که جستجو شده بود پرداختند و در نهایت پس از حذف موارد تکراری، نامرتبط، مطالعات کیفی، مرور روایتی و نامه به سردبیر؛ 18 تحقیق در جهت نگارش این پژوهش، استفاده گردید. از میان مطالعه های مورد بررسی، محل انجام 11 مقاله ایران بود که 11/61 دصد کل مطالعات را نشان میدهد؛ سایر مطالعات در تایوان، چین، آمریکا، اندونزی و سوئیس انجام شده است. میانگین پریشانی اخلاقی پرستاران بخش اورژانس در سطح متوسط و ارتباط معنادار با مولفه هایی همچون سابقه و حجم کار از یافته های این مطالعات بود. نتیجه گیری: مجموعه مطالعات انجام شده بر روی پرستاران بخش اورژانس، برای نشان دادن میزان پریشانی اخلاقی تعداد قابل اطمینانی می باشد، اما این میزان مطالعه برای دستیابی به الگویی از مولفه ها و متغیر های مرتبط با پریشانی اخلاقی، قابل اطمینان نیست. برای این منظور علاوه بر پژوهش های بیشتر بر روی این گروه از پرستاران، می توان با الغای خصوصیت از پرستاران بخش اورژانس، مروری نظام مند بر کل مطالعات انجام شدر در زمینه پریشانی اخلاقی بر روی جامعه پرستاری انجام داد تا به نتایج دقیق تری دست یافت

A case study of Kimura due to grade 1 superficial burn: A rare case report

Kimura (KD) is a rare and chronic inflammatory disease that causes subcutaneous swelling and lymphadenopathy for unknown reasons and usually shows masses such as painless subcutaneous tumors in the head and neck. The disease is diagnosed based on the presence of a characteristic subcutaneous mass, elevated peripheral blood eosinophilia, IgA E levels, and biopsy, which indicates abnormal proliferation of lymph follicles and vascular endothelium with eosinophilic infiltration. Case Report: The patient is a 35-year-old woman who suffered from first degree localized burns in a large area of ​​the body with warm water 2 months before the diagnosis and then the symptoms of Kimura disease appeared in order and after performing several tests and sampling of the disease Proved. Conclusion: It seems that in our patient, a large superficial burn acted as a skin shock and caused the symptoms of Kimura disease, so that the patient showed all the symptoms of this disease within 2 months, including skin symptoms (Dryness, burning, thickening, severe itching and excessive wrinkles), skin rashes on the back of the neck and then swelling in the nose and back of the eyes, and finally an almond-sized mass on the right side of the back Is the neck. The patient has heartburn, loss of appetite and weight loss. His illness has also responded to steroid treatment