Lever, alvleesklier en SLE

Systemische lupus erythematosus (SLE) is een auto-immuunziekte, die in Nederland bij 1 op de 1000 personen voorkomt. Als gevolg van de ziektekomen in verschillende organen ontstekingsprocessen voor. Aangedane organen kunnen onder andere de longen, het hart, de huid en de gewrichten zijn. Wat de oorzaak van deze ontstekingsprocessen is, is niet bekend. Over de ontstekingsprocessen wordt veel gepubliceerd. De Nederlandse Vereniging van Lupus Erythematosus patiënten (N.V.L.E.) komt in de praktijk regelmatig mensen tegen met SLE die tevens een lever- en/of alvleesklieraandoening hebben. Door de N.V.L.E wordt de vraag gesteld aan de wetenschapswinkel of er ook literatuur bekend is over aandoe- ningen aan de lever en alvleesklier bij SLE. Bij hen is hier geen literatuur over bekend. In dit overzicht wordt een korte weergave gegeven van wat er over lever- en alvlees- klieraandoeningen bij SLE bekend is. Om literatuur over dit onderwerp te vinden is gezocht in de algemene leerboeken over reumatologische ziekten. De informatie die gegeven wordt is niet erg specifiek. In Medline is daarna gezocht naar verdere literatuur over dit onderwerp. Aan de hand van algemene uitleg over de werking van de lever en de alvleesklier, zal eerst wat worden gezegd over de lever en SLE, daarna over de alvleesklier en SLE. Aan het eind van de afzonderlijke stukjes over lever en alvleesklier is de gebruikte literatuur weergegeven.

The uniting of Europe and the foundation of EU studies: revisiting the neofunctionalism of Ernst B. Haas

This article suggests that the neofunctionalist theoretical legacy left by Ernst B. Haas is somewhat richer and more prescient than many contemporary discussants allow. The article develops an argument for routine and detailed re-reading of the corpus of neofunctionalist work (and that of Haas in particular), not only to disabuse contemporary students and scholars of the normally static and stylized reading that discussion of the theory provokes, but also to suggest that the conceptual repertoire of neofunctionalism is able to speak directly to current EU studies and comparative regionalism. Neofunctionalism is situated in its social scientific context before the theory's supposed erroneous reliance on the concept of 'spillover' is discussed critically. A case is then made for viewing Haas's neofunctionalism as a dynamic theory that not only corresponded to established social scientific norms, but did so in ways that were consistent with disciplinary openness and pluralism

Interplay of size and Landau quantizations in the de Haas-van Alphen oscillations of metallic nanowires

We examine the interplay between size quantization and Landau quantization in the De Haas-Van Alphen oscillations of clean, metallic nanowires in a longitudinal magnetic field for `hard' boundary conditions, i.e. those of an infinite round well, as opposed to the `soft' parabolically confined boundary conditions previously treated in Alexandrov and Kabanov (Phys. Rev. Lett. {\bf 95}, 076601 (2005) (AK)). We find that there exist {\em two} fundamental frequencies as opposed to the one found in bulk systems and the three frequencies found by AK with soft boundary counditions. In addition, we find that the additional `magic resonances' of AK may be also observed in the infinite well case, though they are now damped. We also compare the numerically generated energy spectrum of the infinite well potential with that of our analytic approximation, and compare calculations of the oscillatory portions of the thermodynamic quantities for both models.Comment: Title changed, paper streamlined on suggestion of referrees, typos corrected, numerical error in figs 2 and 3 corrected and final result simplified -- two not three frequencies (as in the previous version) are observed. Abstract altered accordingly. Submitted to Physical Review

Phase diagram of hot magnetized two-flavor color superconducting quark matter

A two-flavor color superconducting (2SC) Nambu--Jona-Lasinio (NJL) model is introduced at finite temperature T, chemical potential mu and in the presence of a constant magnetic field eB. The effect of (T,mu,eB) on the formation of chiral and color symmetry breaking condensates is studied. The complete phase portrait of the model in T-mu, mu-eB, and T-eB phase spaces for various fixed eB, T, and mu is explored. A threshold magnetic field eB_t~ 0.5 GeV^2 is found above which the dynamics of the system is solely dominated by the lowest Landau level (LLL) and the effects of T and mu are partly compensated by eB.Comment: V1: 29 pages, 15 figures, 3 tables. V2: Discussions improved. Version accepted for publication in PR

Properties of neutral mesons in a hot and magnetized quark matter

The properties of non-interacting $\sigma$ and $\pi^{0}$ mesons are studied at finite temperature, chemical potential and in the presence of a constant magnetic field. To do this, the energy dispersion relations of these particles, including nontrivial form factors, are derived using a derivative expansion of the effective action of a two-flavor, hot and magnetized Nambu--Jona-Lasinio (NJL) model up to second order. The temperature dependence of the pole and screening masses as well as the directional refraction indices of magnetized neutral mesons are explored for fixed magnetic fields and chemical potentials. It is shown that, because of the explicit breaking of the Lorentz invariance by the magnetic field, the refraction index and the screening mass of neutral mesons exhibit a certain anisotropy in the transverse and longitudinal directions with respect to the direction of the external magnetic field. In contrast to their longitudinal refraction indices, the transverse indices of the neutral mesons are larger than unity.Comment: V1: 26 pages, 15 figures; V2: Discussions improved, references added. Version accepted for publication in PR

When Arm’s Length is Too Far:Relationship Banking over the Business Cycle

Using a novel way to identify relationship and transaction banks, we study how banks’ lending techniques affect funding to SMEs over the business cycle. For 21 countries we link the lending techniques that banks use in the direct vicinity of firms to these firms’ credit constraints at two contrasting points of the business cycle. We show that relationship lending alleviates credit constraints during a cyclical downturn but not during a boom period. The positive impact of relationship lending in an economic downturn is strongest for smaller and more opaque firms and in regions where the downturn is more severe

When Arm’s Length is Too Far:Relationship Banking over the Business Cycle

Using a novel way to identify relationship and transaction banks, we study how banks’ lending techniques affect funding to SMEs over the business cycle. For 21 countries we link the lending techniques that banks use in the direct vicinity of firms to these firms’ credit constraints at two contrasting points of the business cycle. We show that relationship lending alleviates credit constraints during a cyclical downturn but not during a boom period. The positive impact of relationship lending in an economic downturn is strongest for smaller and more opaque firms and in regions where the downturn is more severe