17 research outputs found
Developing an effective 2-D urban flood inundation model for city emergency management based on cellular automata
Flash floods have occurred frequently in the urban areas of southern China. An effective process-oriented urban flood inundation model is urgently needed for urban storm-water and emergency management. This study develops an efficient and flexible cellular automaton (CA) model to simulate storm-water runoff and the flood inundation process during extreme storm events. The process of infiltration, inlets discharge and flow dynamics can be simulated with little preprocessing on commonly available basic urban geographic data. In this model, a set of gravitational diverging rules are implemented to govern the water flow in a rectangular template of three cells by three cells of a raster layer. The model is calibrated by one storm event and validated by another in a small urban catchment in Guangzhou of southern China. The depth of accumulated water at the catchment outlet is interpreted from street-monitoring closed-circuit television (CCTV) videos and verified by on-site survey. A good level of agreement between the simulated process and the reality is reached for both storm events. The model reproduces the changing extent and depth of flooded areas at the catchment outlet with an accuracy of 4 cm in water depth. Comparisons with a physically based 2-D model (FloodMap) show that the model is capable of effectively simulating flow dynamics. The high computational efficiency of the CA model can meet the needs of city emergency management
Additional file 6: of The Cambridge Prognostic Groups for improved prediction of disease mortality at diagnosis in primary non-metastatic prostate cancer: a validation study
Table S6. Distribution of cases and deaths from prostate cancer and hazard ratios for each Cambridge Prognostic Group (CPG) in the PCBaSe radical prostatectomy cohort (n = 20,586). (DOCX 15 kb
Additional file 10: of The Cambridge Prognostic Groups for improved prediction of disease mortality at diagnosis in primary non-metastatic prostate cancer: a validation study
Table S10. Cross tabulation of the CPG and three-strata NICE criteria to show the sub-distributions of the cases between the two models in the PCBaSe cohort (n = 72,337). (DOCX 15 kb
Additional file 4: of The Cambridge Prognostic Groups for improved prediction of disease mortality at diagnosis in primary non-metastatic prostate cancer: a validation study
Table S4. Distribution of the Singapore study cohort (n = 2550) by age, PSA at presentation, biopsy Grade Group (GG) and clinical stage (PSA in ng/ml). (DOCX 15 kb
Additional file 8: of The Cambridge Prognostic Groups for improved prediction of disease mortality at diagnosis in primary non-metastatic prostate cancer: a validation study
Table S8. Competing risk regression analysis of the Cambridge Prognostic Group (CPG) by treatment type. A. Radical prostatectomy cohort (n = 20,586), B. radical radiotherapy cohort (n = 11,872) and C. conservative management cohort (n = 14,950). Intergroup comparisons are shown. (DOCX 17 kb
Additional file 1: of The Cambridge Prognostic Groups for improved prediction of disease mortality at diagnosis in primary non-metastatic prostate cancer: a validation study
Table S1. Use of treatments according to Cambridge Prognostic Group (CPG) in the PCBaSe cohort. (DOCX 15 kb
Additional file 9: of The Cambridge Prognostic Groups for improved prediction of disease mortality at diagnosis in primary non-metastatic prostate cancer: a validation study
Table S9. Comparative 10-year prostate cancer mortality rate per 1000 men stratified by treatment type and CPG category in the PCBaSe cohort (n = 72,337) (DOCX 15 kb
Additional file 1: Figure S1. of Betulinic acid enhances TGF-β signaling by altering TGF-β receptors partitioning between lipid-raft/caveolae and non-caveolae membrane microdomains in mink lung epithelial cells
The treatment of BetA does not change the levels of TβR-II, TβR-II, and caveolin-1 in Mv1Lu cells. Figure S2. SB431542 inhibits BetA-enhanced TGF-β-induced fibronectin expression in Mv1Lu cells. (PDF 325 kb
Additional file 5: of The Cambridge Prognostic Groups for improved prediction of disease mortality at diagnosis in primary non-metastatic prostate cancer: a validation study
Table S5. Distribution of cases/deaths and sub-hazard ratios from competing risk analysis for each Cambridge Prognostic Group (CPG) in the Singapore cohort (n = 2550). (DOCX 15 kb
Additional file 2: of The Cambridge Prognostic Groups for improved prediction of disease mortality at diagnosis in primary non-metastatic prostate cancer: a validation study
Table S2. Distribution of the PCBaSe study cohort (n = 72,337) by age, serum PSA at presentation, biopsy Grade Group (GG) and clinical stage (PSA in ng/ml). (DOCX 16 kb