A COMPARATIVE CLINICAL STUDY IN THE MANAGEMENT OF AMAVATA W.S.R TO RHEUMATOID ARTHRITIS THROUGH KSHARA VASTI AND VAITARANA VASTI ALONG WITH SHAMANOUSHADHI

Amavata is a crippling condition where simultaneously aggravated Vata and Ama associated with each other settles in Sandhis and produce Sandhishoola, Sandhishotha, Sparshaasahitwa, which is similar to Rheumatoid Arthritis. The present study has made an attempt to find an effective Ayurvedic treatment modality through Kshara Vasti and Vaitarana Vasti along with Shamanoushadhi. A total of 30 Patients were randomly divided in two groups with 15 patients in each group. In Group A, Kshara Vasti and in Group B, Vaitarana Vasti was given in Yoga Vasti schedule followed by Shamanoushadhi Simhanada Guggulu 500mg twice and Rasna Saptak Kwatha 40ml as Anupana for 45 days in both the groups with 1 month follow-up period. Both Group A and Group B provided highly significant results in all parameters of assessment but Kshara Vasti showed better improvement in the symptoms of the disease Amavata. 63.33% of patients got marked relief, 30% of patients got moderate relief. 56.66% of patients got marked relief in grip strength and 66.66% of the total number of patients got marked relief in tenderness. All the patients of both the groups responded well after Kshara Vasti and Vaitarana Vasti and the result were highly significant. The sustained affect of Vasti was very clearly evident after administration of Vasti along with Shamanoushadhi. Hence the modalities of our treatment can be recommended to all the patients of Amavata

BRICS at the Gate: Modern International Monetary System in Conditions of Balanced Uncertainty

The history of the modern international monetary system has been one of balanced uncertainty, with a fundamental trade-off - and tension - persisting between it anchoring mechanism and the mechanism for adjusting imbalances within. Ever since the system’s moorings drifted from its anchoring to gold and the assured automaticity of convertibility, the adjustment mechanism to regulate intra-systemic imbalances - floating exchange rates, capital controls, coordinated international intervention, or a combination thereof - has had to be progressively scaled upwards to account for the contingent nature of the tie to gold. Attempts to weave this balance have typically tended to break down over time as structural shifts associated with modern capitalism have overwhelmed the founding design of each monetary order. Looking ahead, a 21st century international monetary order that is entirely de-anchored from gold and rests merely on the full faith and credit of its fiat money trustees will necessitate that its mechanisms of international coordination and adjustment to restore balance be ratcheted-upwards equivalently. The emergence of the BRICS (Brazil, Russia, India, China, South Africa) phenomenon, and the powerful re-rise of China as a global strategic peer competitor to the United States, is likely to heap a layer of complication to this task of international financial coordination. To overcome the fundamental structural tensions that exist within the system – semi-liberalized financial and exchange rate regimes in a universe of fully-liberalized and quicksilver capital flows; basic long-term irreconcilability of the United States’ international debtor status with its principal reserve currency-issuer status; viability of a dollar-dominated monetary system in a progressively China, Asia and BRICS-dominated global economic and trading order, we propose that flexibility and capacity be endowed within the system’s regulatory mechanisms to accommodate – and accelerate - the economic and financial liberalization trajectories, and rise, of its BRICS and emerging markets constituents

Comparative thermal performance of static sunshade and brick cavity wall for energy efficient building envelope in composite climate

Energy efficient building technologies can reduce energy consumption in buildings. In present paper effect of designed static sunshade, brick cavity wall with brick projections and their combined effect on indoor air temperature has been analyzed by constructing three test rooms each of habitable dimensions (3.0 m × 4.0 m × 3.0 m) and studying hourly temperatures on typical days for one month in summer and winter each. The three rooms have also been simulated using a software and the results have been compared with the experimental results. Designed static sunshade increased indoor air temperature in winter while proposed brick cavity wall with brick projections lowered it in summer. Combined effect of building elements lowered indoor air temperature in summer and increased it in winter as compared to outdoor air temperature. It is thus useful for energy conservation in buildings in composite climate

Duodenal perforation with Ascaris lumbricoides in a child: A case report

Gastrointestinal infestation with Ascaris lumbricoides is common in temperate and tropical countries. Although heavy worm infestation produces wide range of acute abdominal complications, duodenal perforation in association with ascariasis, especially in children, is rarely reported. We report a case of 5-year-old girl with duodenal perforation secondary to ascariasis

Magnetization dynamics due to field interplay in field free spin Hall nano-oscillators

Spin Hall nano oscillators (SHNOs) have shown applications in unconventional computing schemes and broadband frequency generation in the presence of applied external magnetic field. However, under field-free conditions, the oscillation characteristics of SHNOs display a significant dependence on the effective field, which can be tuned by adjusting the constriction width, thereby presenting an intriguing area of study. Here we study the effect of nano constriction width on the magnetization dynamics in anisotropy assisted field free SHNOs. In uniaxial anisotropy-based field-free SHNOs, either the anisotropy field or the demagnetization field can dominate the magnetization dynamics depending on the constriction width. Our findings reveal distinct auto-oscillation characteristics in narrower constrictions with 20 nm and 30 nm constriction width compared to their wider counterpart with 100 nm width. The observed frequency shift variations with input current and constriction widths stem from the inherent nonlinearity of the system. The interplay between the B_demag and B_anis, coupled with changes in constriction width, yields rich dynamics and offers control over frequency tunability, auto oscillation amplitude, and threshold current. Notably, the spatial configuration of spin wave wells within the constriction undergoes transformations in response to changes in both constriction width and anisotropy. The findings highlight the significant influence of competing fields at the constriction on the field-free auto oscillations of SHNOs, with this impact intensifying as the constriction width is varied.Comment: 25 pages, 11 figure

Phytochemical Investigation and Pharmacological Evaluation of Solanum xanthocarpum Endowed with their potential Activity

The study was done to assess the in-vitro antibacterial potential of various extracts was studied and compared with ciprofloxacin as the standard and shows significant action against E. coli, B. substilis S. aureus, S. pyrogenes, P. aeruginosa, and S. typhi. Anti-fungal potential of the aqueous extract also studied using miconazole as standard and shows significant action against A. niger and C. albicans. Anthelmintic potential of the aqueous and ethanolic extracts was also studied on earthworms, Eudrillus eugeniae using albendazole as standard and shows moderate activity. In the present study in-vitro free radical scavenging activity of whole plant material performed. Various crude extracts of S. xanthocarpum was prepared by successive maceration process using various solvents such as; chloroform, petroleum ether (60-80o), acetone, ethanol and distilled water. Each one extract have been chosen to study the free radical inhibitory activity by DPPH radical scavenging method. The preliminary phytochemical screening of extracts showed that sterols, alkaloids, glycosides, tannins, saponins, phenolic compounds, carbohydrates and proteins were present in the plant. Petroleum ether, chloroform, acetone, ethanol and distilled water extracts showed 52.69, 46.15, 21.08, 52.72 and 44.35 % respectively compared to standard ascorbic acid. Acetone extract showed poor inhibition of DPPH radical compared to standard and other extracts also

Predictors of candidemia in pediatric patients (0–12 years) admitted in a tertiary care hospital of Northern India

Background: Bloodstream infections due to Candida species are becoming a major cause of morbidity and mortality in hospitalized patients. The emergence of non-albicans Candida (NACs) species with lesser susceptibility to antifungals has added to the woes of clinicians. Objectives: The objectives of the study were to determine the clinical and laboratory predictors and microbiological profile of candidemia in pediatric patients. Materials and Methods: This is a hospital-based, prospective, and cross-sectional study conducted in the pediatric department of a tertiary care hospital. A total of 250 children aged 0–12 years with risk factors for fungal sepsis were enrolled. Demographic details, clinical, and laboratory parameters were noted and samples were sent for culture. Cultures yielding growth of Candida were included in the study, and antifungal susceptibility performed. Associations were assessed using Chi-square test first and then through logistic regression models. Results: Among the 250 patients with risk factors for fungal sepsis, 47 patients (18.8%) with culture proven candidemia were identified. Predictors of candidemia among neonates were prematurity (<30 weeks), prolonged ventilation (>72 h), and thrombocytopenia. Among pediatric patients, prolonged steroid intake, Candida isolation from sites other than blood and persistent neutropenia, were significantly associated with the candidemia. NAC species were the predominant isolates (78.7%). Conclusion: Candidemia should be suspected in premature neonates requiring prolonged ventilation with unexplained thrombocytopenia. Among pediatric patients, prolonged steroid intake, Candida isolation from sites other than blood and persistent neutropenia are predictors of candidemia