Use of topical selamectin for the treatment of Syphacia muris infection in laboratory rats

Efficacy of selamectin was studied in naturally acquired S. muris infections in rats. Fourty-eight S. muris-positive rats were divided into six treated and two control groups. Selamectin (6 mg/kg) was applied topically to the skin in a single spot at the base of the neck in the treatment group. The rats of treated and control groups were necropsied on the 24th day after the treatment. Topical selamectin was found to be 40.7-63.3% effective (based on egg per gram method) in eliminating S. muris infection in rats. The efficacy of the treatment against S. muris (based on adult worm counts) in male and female rats was 35.14-58.88%, respectively (mean 48.39%)

Use of topical selamectin for the treatment of Trichosomoides crassicauda infection in laboratory rats

The present study investigated the efficacy of topical selamectin for elimination of naturally acquired Trichosomoides crassicauda infection in rats. Twelve T. crassicauda-positive rats were assigned to the treatment group and six rats were assigned to the control group. Selamectin (6 mg/kg) was applied topically to the skin in a single spot at the base of the neck in front of the scapulae in the treatment group. To assess the efficacy of the treatment, animal faeces were investigated with the use of the flotation technique on days 0, 4, 14 and 24 after selamectin application. The rats of the treatment and control groups were necropsied on the day 24. In the treatment group, 7 of 12 infected rats were cured completely. Topical selamectin was found to be effective in eliminating T crassicauda infection in rats

Therapy of knemidocoptic mange in budgerigars with spot-on application of moxidectin

In this study, 30 Budgerigars (Melopsittacus undulatus) with Knemidocoptes pilae infection were treated with a spot-on application of moxidectin (Cydectin(R) Injection For Cattle) at a dose of 1 mg (0.1 mi Cydectin) per bird. This application was given once to 10 birds and twice at 10 days intervals to 20 birds. Clinical Signs in all birds of both groups disappeared 30-40 days after treatment. No side effects were seen

First molecular diagnosis of Babesia vogeli in domestic dogs from Turkey

Microscopic examination of Giemsa-stained peripheral blood smears collected from three naturally infected dogs originating from Turkey revealed the presence of large (around 4.5-5.0 mu m) intraerythrocytic Babesia parasites in all dogs. DNA was extracted from the three infected blood samples and an around 410 bp portion of the 18 S rDNA gene of Babesia species was PCR amplified for subsequent molecular characterization. RFLP analysis of the PCR products suggested the presence of the species B. vogeli in all infected dogs and sequencing of the PCR products from two of the three samples revealed 100% identity among the two Turkish isolates. Comparisons with the equivalent 4 10 bp portions of the 18 S rDNA gene of Babesia species confirmed the affiliation of these isolates to the B. vogeli species. This is the first report and molecular characterization of dog infection with a large Babesia species in Turkey. (c) 2006 Elsevier B.V. All rights reserved

Efficacy of Moxidectin against strongylin nematodes in naturally infected horses

Twenty naturally infected horses were divided into two groups (10 control and 10 experimental) according to EPG values. An injectable formulation of moxidectin, in a dose of 0.3 mg/kg, was given to the horses orally in jam syrup. The evaluation of drug efficacy was based on EPG values. The same dose of the drug was applied to an additional 25 horses to test for side effects

Experimental visceral larva migrans in chicken with Toxocara canis

The aim of this study was to determine the distribution of Toxocara canis larvae in some organs of chicks and to clarify if the larvae found in brain will be able to lead to the behavioral disorder or not. For this purpose, 42 15-day-old broiler chicks were allocated to 6 groups, each consisted of 5 trial and 2 control animals (Totally 30 exp. and 12 contr. anim.). Each experimental chick recevied 5000 embriyonated T. canis eggs orally. All animals were necropsied between 2(nd) and 12(th) days after inoculation with two day intervals. Brain, lung, liver and a half carcass of animals were digested in the pepsin-HCL solution and the digested organs were examined for the presence of larvae

A survey of Hypodermosis in cattle slaughtered in Thrace (Trakya) Turkey

In this study, a total of 365 cattle (234 male, 131 female) slaughtered in different localities in Thrace (The European part of Turkey) were examined for hypodermosis between January and May of 1997. Hypoderma bovis, H. lineatum and unidentified 2nd instar larvae were found in the skin and subcutaneous tissue of the back region of the animals. The prevalence rate and intensity of infestation were 3.56% and 10.23 respectively