53 research outputs found
Environmental Factors in the Relapse and Recurrence of Inflammatory Bowel Disease:A Review of the Literature
The causes of relapse in patients with Crohn's disease (CD) and ulcerative colitis (UC) are largely unknown. This paper reviews the epidemiological and clinical data on how medications (non-steroidal anti-inflammatory drugs, estrogens and antibiotics), lifestyle factors (smoking, psychological stress, diet and air pollution) may precipitate clinical relapses and recurrence. Potential biological mechanisms include: increasing thrombotic tendency, imbalances in prostaglandin synthesis, alterations in the composition of gut microbiota, and mucosal damage causing increased permeability
Melatonin prevents inflammation and oxidative stress caused by abdominopelvic and total body irradiation of rat small intestine
Dimensions of control and their relation to disordered eating behaviours and obsessive-compulsive symptoms
Background: Issues of personal control have been proposed to play a central role in the aetiology and maintenance of eating disorders. Empirical evidence supporting this relationship is inconsistent, partly due to the multiplicity of constructs used to define "control". This study compares six commonly used measures of control with the aim of determining which operationalisation of control is most centrally relevant to eating pathology. Given the high level of comorbidity between eating disorders and obsessive-compulsive disorder and the potentially common risk/maintenance factors for the two disorders, we also examine the relationship between control and obsessive-compulsive symptomatology. Methods: Female community participants (N = 175) completed self-report measures of control, eating disorder pathology and obsessive-compulsive symptoms. Results: Multivariate analyses of variance indicated significant differences between individuals with high vs. low levels of psychopathology on most of the measures of control. Using regression analyses, we found that a sense of ineffectiveness and fear of losing self-control were the only significant independent predictors of eating pathology, and fear of losing self-control was the most significant predictor of obsessive-compulsive symptoms. Conclusions: This study highlights the importance of issues of control, particularly feelings of ineffectiveness and fear of losing self-control, in eating disorder symptoms. Furthermore, our findings suggest that there may be a similar underlying fear of losing self-control among individuals who engage in disordered eating and obsessive-compulsive behaviours. Thus, ineffectiveness and fear of losing self-control are two dimensions that are important to consider in maintenance and treatment models of disordered eating behaviours
Mechanisms of circulatory and intestinal barrier dysfunction during whole body hyperthermia
The Artificially Stimulated Decidual Cell Reaction in the Mouse Uterus Studies of RNA Polymerases and Histone Modifications
Knock out of neuronal nitric oxide synthase exacerbates intestinal ischemia/reperfusion injury in mice
Alterations in Antioxidant Power and Levels of Epidermal Growth Factor and Nitric Oxide in Saliva of Patients with Inflammatory Bowel Diseases
Measuring Possessions as Extensions of Self and Links to Significant Others in Hoarding: the Possessions as Others and Self Inventory
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