238 research outputs found

    Who Benefits From Teams? Comparing Workers, Supervisors, and Managers

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    This paper offers a political explanation for the diffusion and sustainability of team-based work systems by examining the differential outcomes of team structures for 1200 workers, supervisors, and middle managers in a large unionized telecommunications company. Regression analyses show that participation in self-managed teams is associated with significantly higher levels of perceived discretion, employment security, and satisfaction for workers and the opposite for supervisors. Middle managers who initiate team innovations report higher employment security, but otherwise are not significantly different from their counterparts who are not involved in innovations. By contrast, there are no significant outcomes for employees associated with their participation in offline problem-solving teams

    Assay platform for clinically relevant metallo-beta-lactamases

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    Metallo-β-lactamases (MBLs) are a growing threat to the use of almost all clinically used β-lactam antibiotics. The identification of broad-spectrum MBL inhibitors is hampered by the lack of a suitable screening platform, consisting of appropriate substrates and a set of clinically relevant MBLs. We report procedures for the preparation of a set of clinically relevant metallo-β-lactamases (i.e., NDM-1 (New Delhi MBL), IMP-1 (Imipenemase), SPM-1 (São Paulo MBL), and VIM-2 (Verona integron-encoded MBL)) and the identification of suitable fluorogenic substrates (umbelliferone-derived cephalosporins). The fluorogenic substrates were compared to chromogenic substrates (CENTA, nitrocefin, and imipenem), showing improved sensitivity and kinetic parameters. The efficiency of the fluorogenic substrates was exemplified by inhibitor screening, identifying 4-chloroisoquinolinols as potential pan MBL inhibitors

    Management

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    Bisnis internasional. : V. 2. : Perspektif manajerial.

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    JakartaV. 2.; xxv, 335 p.; 28 cm

    BISNIS INTERNASIONAL:PERSPEKTIF MANAJERIAL JILID 1/P-05

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    316hlm;20,5x27,5c

    Bisnis : Jilid 2

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    JakartaJil. 2 xxii, 339 hlm.; 28 c

    Manajemen. : V. 1.

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    JakartaV. 1.; xix, 452 p.; 28 cm

    MANAJEMEN JILID 2/P-07

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    xviii+271hlm;21x28c

    MANAJEMEN JILID 1/P-07

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    xvi+452hlm;21x28c

    Bisnis 2

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    judul asli business, Jil.2xx, 290 p. : il.; 26 c
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