380 research outputs found
Fabrication of Metasurfaces on Building Construction Materials for Potential Electromagnetic Applications in the Microwave Band
Energy self sufficiency, as well as optimal management of power in buildings
is gaining importance, while obtaining power from traditional fossil energy
sources is becoming more and more expensive. In this context, millimeter scale
metasurfaces can be employed to harvest energy from microwave sources. They can
also be used as sensors in the microwave regime for efficient power management
solutions. In the current study, a simple spray printing method is proposed to
develop metasurfaces in construction materials, i.e., plasterboard and wood.
Such materials are used in the interior design of buildings; therefore, the
implementation of metasurfaces in large areas, such as walls, doors and floors,
is realized. The fabricated metasurfaces were characterized regarding their
electromagnetic performance. It is hereby shown that the investigated
metasurfaces exhibit an efficient electromagnetic response in the frequency
range 4 to 7 GHz, depending on the MS. Thus, spray printed metasurfaces
integrated on construction materials can potentially be used for
electromagnetic applications, for buildings power self efficiency and
management.Comment: 14pages, 8 figure
SGLT2 αναστολείς και νεφροπροστασία
Ένας στους δύο ασθενείς με σακχαρώδη διαβήτη τύπου ΙΙ (ΣΔ) παρουσιάζει χρόνια νεφρική νόσο (XNN) και κάποιοι από αυτούς θα οδηγηθούν σε χρόνια νεφρική νόσο τελικού σταδίου, ενώ παράλληλα παρουσιάζουν υψηλό καρδιαγγειακό κίνδυνο. Ακόμη και με την ευρεία χρήση των αναστολέων του συστήματος ρενίνης-αγγειοτενσίνης-αλδοστερόνης ο κίνδυνος για νεφρική εξέλιξη υπάρχει. Ο συμμεταφορέας νατρίου-γλυκόζης (SGLT2) στο νεφρό προκαλεί δυναμική επαναρρόφηση της διηθούμενης γλυκόζης μαζί με το νάτριο. Οι αναστολείς αυτών των υποδοχέων (SGLT2i) αρχικά σχεδιάστηκαν και αναπτύχθηκαν ως φάρμακα για αντιδιαβητική χρήση, με σκοπό τη μείωση της υπεργλυκαιμίας. Απρόσμενα κατέγραψαν μία στατιστικά σημαντική μείωση στον κίνδυνο θανάτου, καρδιαγγειακών συμβάντων και εξέλιξης της ΧΝΝ. Ο ρόλος των SGLT2i να μειώνουν την καρδιαγγειακή θνητότητα και να βελτιώνουν τη διατήρηση του ρυθμού σπειραματικής διήθησης έχει αποδειχτεί από αρκετές τυχαιοποιημένες μελέτες. Οι νεφρικές τους δράσεις φαίνονται να είναι πλειοτροπικές επηρεάζοντας άμεσα και έμμεσα το νεφρό. H αναστολή των SGLT2 καθίσταται πλέον απαραίτητη στη θεραπεία της διαβητικής νεφροπάθειας. Ακόμη πιο πρόσφατα, η ωφέλιμη νεφρική δράση τους επεκτείνεται και σε ασθενείς χωρίς ΣΔ. Στην παρούσα βιβλιογραφική ανασκόπηση αναλύονται οι μηχανισμοί με τους οποίους οι SGLT2i προάγουν τα νεφρικά οφέλη, όπως επίσης καταγράφονται και τα νεφρικά αποτελέσματα από τις κυριότερες τυχαιοποιημένες μελέτες σε πληθυσμό με ή χωρίς ΣΔ.One out of two patients with type 2 diabetes develop a certain degree of renal impairment and in many of them chronic kidney disease progresses to end-stage renal disease with increased risk of cardiovascular mortality. Although, renin-angiotensin system blockers are usually be used, a substantial residual risk of renal progression remains. The SGLT2 protein reabsorbs glucose and sodium in the kidney. The inhibitors of SGLT2 were firstly designed and developed for their hypoglycemic effect, but surprisingly reported a statistical significant reduction of overall mortality, cardiovascular risk and renal progression. The role of SGLT2i in the reduction of cardiovascular mortality and the preservation of the estimated glomerular filtration rate has been reported in many randomized controlled trials. The renal effects are pleiotropic and consist of direct and indirect effects. The SGLT2i have become important treatment target for the diabetic nephropathy. Recently, the beneficial role of SGLT2 have expanded in patients without diabetes. This review outlines the mechanisms, whereby the SGLT2s promote the renal effects, as well as the renal outcomes from the most important randomized trials in patients with or without diabetes
Dielectric properties of Granodiorite partially saturated with water and its correlation to the detection of seismic electric signals
Transient electric signals emitted prior to earthquake occurrence are
recorded at certain sites in the Earth's crust termed sensitive. These field
observations enforce the laboratory investigation of the dielectric response of
rocks forming these localities. The dielectric relaxation of granodiorite rock
coming from such a sensitive locality (Keratea, Greece) reveals, through
complex impedance spectroscopy, that the activation volume for relaxation of
this rock is negative which so far has been reported only rarely. This result,
however, supports a theoretical model on the pre-seismic electric signals and
is likely to be correlated with the sensitivity of the site and hence with the
selectivity
Negative activation volume for dielectric relaxation in hydrated rocks
Negative defect activation volumes are extremely rare in solids. Here, we
report for the first time that this holds in a couple of hydrated rocks for
dielectric relaxation by exploring the complex impedance spectra at various
pressures and temperatures. The present findings mean that the relaxation time
of the relevant relaxation mechanisms decreases upon increasing pressure, thus
it may become too short at higher pressure and hence lead to the emission of
transient electric signals before fracture. This may constitute the
long-standing laboratory confirmation for the explanation of the generation of
electric signals prior to an earthquake, as recently pointed out by Uyeda et al
[Tectonophysics 470 (2009) 205-213]
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