3 research outputs found

    Plan de mejoramiento para la renovación de los sistemas de comunicación en fiduprevisora.

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    Diseñar un plan de mejoramiento para la renovación del sistema de comunicación en Fiduprevisora, facilitando así el crecimiento tecnológico según las necesidades del negocio.El presente trabajo se da como la respuesta a la problemática identificada con el sistema de comunicaciones en la entidad Fiduprevisora, para el que inicialmente se realiza un diagnóstico que permita reconocer las debilidades y fortalezas del sistema actual por medio de reuniones con el director de infraestructura se logra además esclarecer las necesidades de la entidad, buscando asegurar el cumplimiento de los parámetros de seguridad exigidos por la Superintendencia financiera de Colombia en las circular 007 de 2018, circular 052 de 2007, circular 042 de 2012, además teniendo en cuenta la capacidad técnica a lograr, para lo que se plantea un plan de mejoramiento que permita subsanar los hallazgos evidenciados durante el diagnóstico.The present work is given as the answer to the problem identified with the communications system in the Fiduprevisora entity, for which initially a diagnosis is made that allows recognizing the weaknesses and strengths of the current system through meetings with the director of infrastructure. It also manages to clarify the needs of the entity, seeking to ensure compliance with the security parameters required by the Financial Superintendence of Colombia in circular 007 of 2018, circular 052 of 2007, circular 042 of 2012, also taking into account the technical capacity to achieve, for which an improvement plan is proposed to correct the findings evidenced during the diagnosis

    Highly Efficient Autologous HIV-1 Isolation by Coculturing Macrophage With Enriched CD4+ T Cells From HIV-1 Patients

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    We described a novel HIV autologous isolation method based in coculturing macrophages and CD4+T-cell-enriched fractions from peripheral blood collected from antiretroviral-treated (ART) HIV patients. This method allows the isolation of high viral titers of autologous viruses, over 1010HIV RNA copies/ml, and reduces the time required to produce necessary amounts for virus for use as antigens presented by monocyte-derived myeloid cells in HIV therapeutic vaccine approaches. By applying these high titer and autologous virus produced in the patient-derived cells, we intended to elicit a boost of the immunological system response in HIV therapeutic vaccines in clinical trials.This study was partially supported by grants from the Spanish Ministry of Economy (MINECO) (grants: SAF2015-66193-R, SAF-2017-88089-R, RTI2018-096309-B-I00); the Fondo Europeo para el Desarrollo Regional (FEDER); the SPANISH AIDS Research Network RD16/0025/0002 and RD16/0025/0014-ISCIII-FEDER (RIS); the Fondo de Investigación Sanitaria (FIS) PI12/01247 and PI20/00676; and HIVACAT program and the CERCA Programme/Generalitat de Catalunya SGR 615 and SGR 653. The project leading to these results has received funding from “la Caixa” Foundation under agreement. This study was also supported in part with federal funds from the National Cancer Institute, National Institutes of Health, under contract Nos. HHSN261200800001E and 75N91019D00024.S
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