20 research outputs found

    The acceptance of a prototype rear-view assistant for older cyclists: Two modalities of warnings compared

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    The aim of this study was to evaluate the effects on behaviour, mental effort and acceptance of a simple prototype of an electronic rear-view assistance system designed for older cyclists that are at risk of falls. The prototype was incorporated into a simple cycling simulator and provided information about traffic from behind in two modalities: visual and haptic. Twenty-one older participants (>64 years) completed three conditions: warnings in two modalities and a control condition without warnings. Mental effort and acceptance were assessed using subjective rating scales and by monitoring changes in cycling speed. Less mental effort was reported when using the rear-view assistant. Significantly more correct decisions regarding a safe left turn were made with system advice. No significant speed differences were found between the two modality conditions. It is concluded that the electronic rear-view assistance system can potentially support the older cyclist successfully by warning for traffic coming from behind

    The acceptance of a prototype rear-view assistant for older cyclists: two modalities of warnings compared

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    The aim of this study was to evaluate the effects on behaviour, mental effort and acceptance of a simple prototype of an electronic rear-view assistance system designed for older cyclists that are at risk of falls. The prototype was incorporated into a simple cycling simulator and provided information about traffic from behind in two modalities: visual and haptic. Twenty-one older participants (>64 years) completed three conditions: warnings in two modalities and a control condition without warnings. Mental effort and acceptance were assessed using subjective rating scales and by monitoring changes in cycling speed. Less mental effort was reported when using the rear-view assistant. Significantly more correct decisions regarding a safe left turn were made with system advice. No significant speed differences were found between the two modality conditions. It is concluded that the electronic rear-view assistance system can potentially support the older cyclist successfully by warning for traffic coming from behind

    Donor age and red cell age contribute to the variance in lorrca indices in healthy donors for next generation ektacytometry: A pilot study.

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    The ability of red blood cells (RBCs) to transport gases, their lifespan as well as their rheological properties invariably depend on the deformability, hydration, and membrane stability of these cells, which can be measured by Laser optical rotational red cell analyser (Lorrca® Maxsis, RR Mechatronics). The osmoscan mode of Lorrca is currently used in diagnosis of rare anemias in clinical laboratories. However, a broad range of normal values for healthy subjects reduces the sensitivity of this method for diagnosis of mild disease phenotype. In this pilot study, we explored the impact of age and gender of 45 healthy donors, as well as RBC age on the Lorrca indices. Whereas gender did not affect the Lorrca indices in our study, the age donors had a profound effect on the O_hyper parameter. To study the impact of RBC age on the osmoscan parameters, we have isolated low (L)-, medium (M)-, or high (H)- density fractions enriched with young, mature, and senescent RBCs, respectively, and evaluated the influence of RBC age-related properties, such as density, morphology, and redox state, on the osmoscan indices. As before, O_hyper was the most sensitive parameter, dropping markedly with an increase in RBC density and age. Senescence was associated with a decrease in deformability (EI_max) and tolerability to low and high osmolatites (Area). L-fraction was enriched with reticulocytes and cells with high projected area and EMA staining, but also contained a small number of cells small in projected area and most likely, terminally senescent. L-fraction was on average slightly less deformable than mature cells. The cells from the L-fraction produced more oxidants and NO than all other fractions. However, RBCs from the L-fraction contained maximal levels of reduced thiols compared to other fractions. Our study suggests that reference values for O_hyper should be age-stratified, and, most probably, corrected for the average RBC age. Further multi-center study is required to validate these suggestions before implementing them into clinical practice
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