5,760 research outputs found

    Remembering to Look Down: A Thing not a Thesis

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    Thoughts on magic, spectacle, arena, material, materiality, marrow, invincibility, repetition, performance, sculpture, time, decay, temporality, tools, marks, gestures, writing, coaxing, site, stage, architecture, and movement

    Alien Registration- Mcmahon, George M. (Millinocket, Penobscot County)

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    https://digitalmaine.com/alien_docs/7765/thumbnail.jp

    Comparison of a Numeric and a Descriptive Pain Scale in the Occupational Medicine Setting

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    Pain is a universal phenomenon. The assessment of a patient’s pain is difficult to objectively obtain because the perception of the pain by the patient is influenced by many subjective perception variables. These variables can inflate or deflate the patient’s self-reported pain level which can adversely affect the medical provider’s ability to accurately create a treatment plan for the patient. This study compared the patient’s response to a self-rating of their pain on a numeric pain scale with the response given by the patient on the Mankoski pain scale. Comparison of the numeric pain scale to the Mankoski pain scale indicated a significant relationship between the two scales, r (218) = .83, p \u3c .05, validating the Mankoski pain scale with acute pain patients. Although not statistically significant, the Mankoski mean score was lower compared to the numeric scores of 3, 4, 5, and 6 and was statistically significantly lower for the numeric scores of 7, 8, and 9

    Spectroscopic and Computational Studies of Matrix-Isolated iso-CXBr3 (X=F,Cl,Br): Structure, Properties, and Photochemistry of Substituted Iso-Tribromomethanes

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    Iso-polyhalomethanes are important reactive intermediates in the condensed and gas-phase chemistry of halomethanes. Building upon our recent study of iso-bromoform, in this work the substituted iso-tribromomethanes (iso-CXBr3; X = F, Cl, Br) were characterized by matrix isolation infrared and UV/Vis spectroscopy, supported by ab initio calculations, to further probe the structure, spectroscopy, properties, and photochemistry of these important intermediates. Selected wavelength laser irradiation of CXBr3 samples in an inert rare gas (typically Ar; mixing ratio 1:500) held at ∼5 K yielded iso-CXBr3 (XBrC–Br–Br or Br2C–Br–X). The observed infrared and UV/Vis absorptions are in excellent agreement with computational predictions, and the energies of various stationary points on the CXBr3 Potential Energy Surfaces (PESs) were characterized computationally using DFT, MP2, and CCSD (T) methods in combination with triple-zeta quality basis sets. These calculations show that the isomers are minima on the PESs that lie ∼200 kJ/mol above the global CXBr3 minimum, yet are bound by some 50–70 kJ/mol in the gas-phase with respect to the CXBr2 + Br asymptote. Laser irradiation of the isomers resulted in back photoisomerization to CXBr3, and intrinsic reaction coordinate (IRC) calculations confirmed the existence of a first order saddle point connecting the two isomers. Calculations of important stationary points on the CXBr3 PESs show that in the gas-phase the isomerization barrier lies energetically near the threshold for simple bond fission. The iso-CXBr3 species are significantly stabilized in the condensed phase, due to the high degree of ion-pair character, as revealed by Natural Resonance Theory analysis

    The Duty to Deal under Section 46: Panacea or Pandora\u27s Box?

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    The privatisation and restructuring of public monopolies and the deregulation of other essential services in Australia and other countries have focused attention on the need for rules which can foster competition and efficiency in the resulting markets. Australia, of course, already has the Trade Practices Act 1974 (Cth) (the Act ), and the question that has been raised is whether the Act is adequate to deal with the kind of competitive problems that are likely to arise in such markets. Of particular concern is the situation in which a firm controls the supply of an input that is critical in the production of another downstream product, but refuses to supply that input to certain potential suppliers of the downstream product or does so only on terms that render it impossible for those downstream firms to be effective competitors. Under s 46 of the Act, a duty to deal can be imposed on a corporation with substantial market power, and there have been several cases in recent years seeking precisely such a remedy. Hence, it could be argued that s 46 ought to be adequate to deal with whatever problems of access might arise as a result of privatisation and deregulation. This article attempts to demonstrate that the ability of s 46 to deal effectively with problems of access has been oversold. Indeed, we will claim that, except under special circumstances, any effort to impose a duty to deal on a monopolist will at best be ineffective and at worst be counterproductive. If significant pockets of monopoly power are likely to persist in some of the markets affected by recent legislative restructurings, other measures may be necessary if consumers are to enjoy the full benefits of competition. Such measures may or may not be forthcoming. But at the very least, Australian courts should not use s 46 in a way that reduces efficiency and operates to the long run detriment of consumers

    Leadership Practices of School Counselors

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    Leadership is a vital skill called for by the school counseling profession. However, limited research has been done to examine how leadership is characterized by practicing school counselors. The purpose of the exploratory study in this article was to assess leadership practices of school counselors, and to analyze the relationships among demographics, experience, training, work setting, and leadership practices. Results presented are part of a larger study. Findings revealed that age, experience, size of school population, and professional licensure predicted leadership practices of school counselors

    The Duty to Deal under Section 46: Panacea or Pandora\u27s Box?

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    The privatisation and restructuring of public monopolies and the deregulation of other essential services in Australia and other countries have focused attention on the need for rules which can foster competition and efficiency in the resulting markets. Australia, of course, already has the Trade Practices Act 1974 (Cth) (the Act ), and the question that has been raised is whether the Act is adequate to deal with the kind of competitive problems that are likely to arise in such markets. Of particular concern is the situation in which a firm controls the supply of an input that is critical in the production of another downstream product, but refuses to supply that input to certain potential suppliers of the downstream product or does so only on terms that render it impossible for those downstream firms to be effective competitors. Under s 46 of the Act, a duty to deal can be imposed on a corporation with substantial market power, and there have been several cases in recent years seeking precisely such a remedy. Hence, it could be argued that s 46 ought to be adequate to deal with whatever problems of access might arise as a result of privatisation and deregulation. This article attempts to demonstrate that the ability of s 46 to deal effectively with problems of access has been oversold. Indeed, we will claim that, except under special circumstances, any effort to impose a duty to deal on a monopolist will at best be ineffective and at worst be counterproductive. If significant pockets of monopoly power are likely to persist in some of the markets affected by recent legislative restructurings, other measures may be necessary if consumers are to enjoy the full benefits of competition. Such measures may or may not be forthcoming. But at the very least, Australian courts should not use s 46 in a way that reduces efficiency and operates to the long run detriment of consumers

    Genome-wide association study identifies common and low-frequency variants at the AMHgene locus that strongly predict serum AMH levels in males

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    Anti-Müllerian hormone (AMH) is an essential messenger of sexual differentiation in the foetus and is an emerging biomarker of postnatal reproductive function in females. Due to a paucity of adequately sized studies, the genetic determinants of circulating AMH levels are poorly characterized. In samples from 2815 adolescents aged 15 from the ALSPAC study, we performed the first genome-wide association study of serum AMH levels across a set of ∼9 M ‘1000 Genomes Reference Panel’ imputed genetic variants. Genetic variants at the AMH protein-coding gene showed considerable allelic heterogeneity, with both common variants [rs4807216 (PMale = 2 × 10−49, Beta: ∼0.9 SDs per allele), rs8112524 (PMale = 3 × 10−8, Beta: ∼0.25)] and low-frequency variants [rs2385821 (PMale = 6 × 10−31, Beta: ∼1.2, frequency 3.6%)] independently associated with apparently large effect sizes in males, but not females. For all three SNPs, we highlight mechanistic links to AMH gene function and demonstrate highly significant sex interactions (PHet 0.0003–6.3 × 10−12), culminating in contrasting estimates of trait variance explained (24.5% in males versus 0.8% in females). Using these SNPs as a genetic proxy for AMH levels, we found no evidence in additional datasets to support a biological role for AMH in complex traits and diseases in men

    The genetics and epidemiology of myopia in the ALSPAC cohort

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    An aim of this thesis is to map a genetic factor that is related to myopia progression. A genome-wide association study of myopia, refractive error and two ocular determinants of refractive error, axial length and corneal curvature was undertaken. A number of genetic locations were identified and extra genotyping and replication in an independent cohort is underway. A further aim of this thesis is investigation of an environmental risk factor of myopia. Epidemiological analyses of two myopia risk factors were undertaken; one in the ALSPAC cohort, another in a cohort from Northern England. In both cases, a relationship with myopia was identified and a plausible mechanism for the relationship is discussed.EThOS - Electronic Theses Online ServiceGBUnited Kingdo
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