20 research outputs found
Synthesis and study of cyclic indole-based oligomers as new G-quadruplex ligands and potential anticancer agents
Get PDFSynthesis and study of cyclic indole-based oligomers as new G-quadruplex ligands and potential anticancer agents
Get PDFOligomeri di eterocilci aromatici come inibitori della telomerasi: progettazione e sintesi
No full textA hydrophilic three side-chained triazatruxene as a new strong and selective G-quadruplex ligand
No full textA new hydrosoluble triazatruxene derivative (AZATRUX) is reported to selectively bind to G-quadruplex DNA, as derived by ESI-MS measurements and competition experiments. © The Royal Society of Chemistry 2009
Ciclotrimeri simmetrici di eterocicli aromatici come ligandi selettivi di strutture g-quadruplex su dna telomerico umano: nuovi potenziali antitumorali
No full textNuovi macrocicli a scheletro ammidico di eterocicli azotati come ligandi del DNA G-quadruplex
No full textNEW HYDROPHILIC THREE SIDE-CHAINED TRIAZATRUXENE DERIVATIVES AS STRONG AND SELECTIVE G-QUADRUPLEX LIGANDS
No full textDerivati trisostituiti idrosolubili del triazatruxene: potenti e selettivi ligandi del DNA G-quadruplex
No full textNEW HYDROPHILIC THREE SIDE-CHAINED TRIAZATRUXENE DERIVATIVES AS STRONG AND SELECTIVE G-QUADRUPLEX LIGANDS
No full textStudy of a Convenient Method for the Preparation of Hydrosoluble Fluorescent Triazatruxene Derivatives
No full textTriazatruxene derivatives find many applications as lipophilic compounds, but few examples of hydrosoluble derivatives have been reported so far. In this paper, we compare different synthetic routes for the preparation of hydrophilic triazatruxene derivatives and define the most versatile path-way. The synthesized compounds are fluorescent not only in organic solvents, as reported for other lipophilic derivatives, but also in water, making them particularly suitable for biological applications
