Variación en el color de la carne de terneros pasteros

3 páginas, 3 tablas.-- Ponencia presentada a las VIII Jornadas sobre Producción animal (AIDA) (Zaragoza 11 a 13 de mayo de 1999). Publicada en un número especial de la revista ITEA.De los múltiples parámetros que pueden ser evaluados para definir la calidad de la carne es de destacar el color, por su influencia en las preferencias de los consumidores por uno u otro tipo de carne, al ser apreciado de forma directa en los puntos de venta. Ha sido puesto de manifiesto por distintos autores, (Renerre, 1990; Mandel et al, 1998, Albertí, Sañudo, 1998) la influencia que sobre la intensidad de color de la carne de vacuno puede tener el genotipo, el ejercicio físico, la alimentación, la edad de los animales, los tratamientos post-mortem de la carne etc. Cuando se pretende producir carne a partir de terneros pasteros, el color de ésta puede ser una característica importante por la influencia de la actividad física de los animales y la ingestión de forrajes verdes. Sin embargo, el periodo de acabado, previo al sacrificio podría determinar variaciones en la intensidad del color de la carne producida. Por todo ello, el objetivo de este trabajo ha sido el estudio de los parámetros definitorios del color de la carne (L*, a* y b*) y la concentración de pigmentos hemínicos en músculo, de terneros pasteros sometidos a distintas estrategias de alimentación durante el periodo de acabado.Este trabajo ha sido realizado como parte del contrato de investigación entre la empresa ‘Núcleo de Explotaciones Agropecuarias de León, NEAL. SA.” y el CSIC y gracias a la colaboración prestada por la Estación Tecnológica de la Carne de la Junta de Castilla y León.Peer reviewe

Влияние крупности кварцевого сырья на кинетику процесса образования карбида кремния

AbstractThe joint European research project ELVA brings in line technology options and customer expectations for third generation electric vehicles. The objective is to develop innovative vehicle architectures fully exploiting freedoms in design that result from the electric drivetrain. This paper summarises the results of the first phase of the project which comprised deep technology and market forecasting as well as an open design contest for future electric vehicles. In the end, an outlook is given for the next phase in which three detailed vehicle concepts will be virtually developed and assessed with regard to several key requirements such as energy efficiency, material application and safety

Severe Early-Onset Obesity Due to Bioinactive Leptin Caused by a p.N103K Mutation in the Leptin Gene.

CONTEXT: Congenital leptin deficiency is a very rare cause of severe early-onset obesity. We recently characterized a mutation in the leptin gene (p.D100Y), which was associated with detectable leptin levels and bioinactivity of the hormone. CASE DESCRIPTION: We now describe two siblings, a 9-year-old girl and a 6-year-old boy with severe early-onset obesity and hyperphagia, both homozygous for a c.309C>A substitution in the leptin gene leading to a p.N103K amino acid exchange in the protein and detectable circulating levels of leptin. In vitro experiments in a heterologous cell system demonstrated that the mutated protein was biologically inactive. Treatment with sc recombinant human leptin led to rapid improvement of eating behavior and weight loss. CONCLUSIONS: Sequencing of the leptin gene may need to be considered in hyperphagic, severely obese children with detectable levels of circulating leptin.This work was supported by Grant BMBF 01GI1120A from the Federal Ministry of Education and Research. Support was also provided by the Wellcome Trust (082390/Z/07/Z), the Medical Research Council, the National Institute for Health Research Cambridge Biomedical Research Centre, the European Research Council, and the Bernard Wolfe Health Neuroscience Fund (all to I.S.F.). J.-B.F. was supported by the International Graduate School in Molecular Medicine Ulm.This is the final version of the article. It first appeared from the Endocrine Society via http://dx.doi.org/10.1210/jc.2015-226

CD90 is dispensable for white and beige/brown adipocyte differentiation

Brown adipose tissue (BAT) is a thermogenic organ in rodents and humans. In mice, the transplantation of BAT has been successfully used to combat obesity and its comorbidities. While such beneficial properties of BAT are now evident, the developmental and cellular origins of brown, beige, and white adipocytes have remained only poorly understood, especially in humans. We recently discovered that CD90 is highly expressed in stromal cells isolated from human white adipose tissue (WAT) compared to BAT. Here, we studied whether CD90 interferes with brown or white adipogenesis or white adipocyte beiging. We applied flow cytometric sorting of human adipose tissue stromal cells (ASCs), a CRISPR/Cas9 knockout strategy in the human Simpson-Golabi-Behmel syndrome (SGBS) adipocyte model system, as well as a siRNA approach in human approaches supports the hypothesis that CD90 affects brown or white adipogenesis or white adipocyte beiging in humans. Taken together, our findings call the conclusions drawn from previous studies, which claimed a central role of CD90 in adipocyte differentiation, into question

Strahlphysikalische Aspekte des Targetbetriebs bei Hera-B

Das HERA­B Target wird zur Erzeugung von Proton­Nukleon Wechselwirkungen am HERA­Protonen Speicherring betrieben. Dazu sind acht Drahttargets um den HERA­Protonenstrahl angeordnet. Der Abstand dieser Drahttar­ gets zum Zentrum des Protonenstrahls wird ständig so geregelt, daß die Wechselwirkungsrate möglichst konstant bleibt und jedes der Targets gleichmäßig zur Gesamtrate beiträgt. Wichtig für die Rekonstruktion der Wechselwirkungen im HERA­B Detektor ist, daß zeitlich zwischen den in HERA umlaufenden Protonenbündeln keine Wechselwirkungen auftreten und daß keine zu großen Fluktuationen der Wechselwirkungsrate auftreten. Diese Arbeit beschreibt den für die präzise Regelung der Wechselwirkungsrate essentiellen mechanischen Aufbau des HERA­B Targetsystems und die im Rahmen einer Neukonstruktion durchgeführten Verbesserungen im Vergleich zur vorher eingesetzten Targetmechanik. Mit dem Targetsystem wurden zeitlich zwischen den Bunchen nicht erwünschte Wechselwirkungen der Strahlprotonen an den Targets beobachtet. Diese Coasting­Beam Wechselwirkungen wurden im Rahmen der vorliegenden Arbeit eingehend untersucht. Die Untersuchungen zeigen, daß der beobachtete Coasting­Beam aus mehreren Komponenten besteht, die durch ihre Energieabweichung relativ zur Sollenergie und ihre Lebensdauer klassifiziert werden können. Mögliche Produktionsmechanismen für die einzelnen Komponenten werden diskutiert. Desweiteren wurde das Prinzip der Modulation des Speicherringtune zur Reduktion von Fluktuationen der Wechselwirkungsrate untersucht. Mit Hilfe einer Ein­Teilchen­Simulation wird das Prinzip der Tune­Modulation im Detail erläutert. Es wird gezeigt, daß die Modulation die Diffusion der Protonen im Arbeitsbereich des Targets vergrößert. Diese zusätzliche Diffusion führt zu kleineren Ratenfluktuatioen, wie Messungen mit dem beschriebenen Targetsystem zeigen.The HERA­B target is operated to produce proton­nucleon interactions at the HERA proton storage ring. Therefore eight wire targets are arranged around the HERA proton beam. The distance of these wire targets to the center of the proton beam is continously steered in such a way that the interaction rate remains as constant as possible and that each of the targets contributes equally to the total rate. For the reconstruction of ebvents in the HERA­B detector it is important that no interactions arise in the time slots between the proton bunches rotating in HERA and that there are no large fluctuations of the interaction rate. This work describes the mechanics of the HERA­B target system, which is essential for the precise steering of the interaction rate, and summarizes the accomplished improvements of a newly constructed mechanics in comparison to the previously used target mechanics. While operating the target system not desired interactions in the time slots between the proton bunches of the beam were observed at the target. These coasting beam interactions are examined in detail in this work. The examinati­ ons show that the observed coasting beam consists of several components, which can be classified by their energy deviation relative to the nominal energy and their lifetime. Possible production mechanisms are discussed for the individual components. Furthermore the principle of modulating the storage ring tune was examined for the reduction of fluctuations of the interaction rate. With the help of a single particle simulation the principle of the tune modulation is described in detail. It is shown that the modulation increases the diffusion of the protons in the working area of the target. The increased diffusion leads to smaller fluctuations of the interaction rate, which is shown using measurements of the described target system