Posterior means and 95% posterior credibility intervals (PCI) of sensitivities (Se) and specificities (Sp) for the PCR tests performed in bulk tank milk (PCR BTM) and indoor dust samples (PCR DUST), for the 2 models with different priors for the specificity of PCR DUST.

<p>PCR BTM (n = 380) and PCR DUST (n = 380) tests were performed in 95 dairy cattle herds in the Finistère department, France between November 2012 and April 2014.</p

Experimental variogram of the observed dates of detection of Bluetongue virus serotype 8 clinical signs of reported case herds (dots) and the fitted nested model of semivariogram (solid black line) which is the sum of a nugget effect, an exponential and a Gaussian variogram model.

<p>The gaussian component which is kept for kriging is shown in red dashed line.</p

Geographical location of cattle herds in the outbreak area: (a) 8,313 case herds reported after clinical signs of Bluetongue virus serotype 8 (BTV-8) in 2007, (b) 74,169 non-reported herds (e.g., herds with an interpolated date of BTV-8 exposure); 2007; France.

<p>Geographical location of cattle herds in the outbreak area: (a) 8,313 case herds reported after clinical signs of Bluetongue virus serotype 8 (BTV-8) in 2007, (b) 74,169 non-reported herds (e.g., herds with an interpolated date of BTV-8 exposure); 2007; France.</p

Posterior means and 95% posterior credibility intervals (PCI) of sensitivities (Se) and specificities (Sp) of the tests combined in parallel or serial reading (2 PCR tests performed in bulk tank milk, PCR BTM, and indoor dust samples, PCR DUST) for the 2 models with different priors for the specificity of PCR DUST.

<p>PCR BTM (n = 380) and PCR DUST (n = 380) tests were performed in 95 dairy cattle herds in the Finistère department, France between November 2012 and April 2014.</p

Kriging map of the dates of detection of Bluetongue virus serotype 8 clinical signs, expressed as a number of days since the first clinical case herd during the 2007 epizootic in France (31^st July 2007), and location of reported case herds (black crosses).

<p>The hatched areas correspond to regions with no data.</p

Hazard Ratio (HR) of 90-d-return-to-service before and after (a) the date of Bluetongue virus serotype 8 (BTV-8) clinical detection for case herds reported during the 2007 epizootic, (b) the interpolated date of BTV-8 clinical detection for non-reported herds located in the 2007 outbreak area, (c) the transposed date in a previous year free of BTV (2005) for herds in 2005 located in the 2007 outbreak area, France.

<p>Hazard Ratio (HR) of 90-d-return-to-service before and after (a) the date of Bluetongue virus serotype 8 (BTV-8) clinical detection for case herds reported during the 2007 epizootic, (b) the interpolated date of BTV-8 clinical detection for non-reported herds located in the 2007 outbreak area, (c) the transposed date in a previous year free of BTV (2005) for herds in 2005 located in the 2007 outbreak area, France.</p

Effect of adjustment variables on risk of 90-day-return-to-service for cows which underwent artificial insemination (AI) between 10 weeks before and 14 weeks after the observed date of Bluetongue virus serotype 8 (BTV-8) detection (2,646 case herds), the interpolated date of BTV-8 clinical detection (5,237 non-reported herds) and the transposed date in a year free of BTV-8 (8,215 herds in 2005 located in the 2007 outbreak area).

<p>*95% Confidence interval.</p>#<p>Classes were constituted according to the distribution of the milk yield production and the lactation number.</p>§<p>Month of service in 2007 for cows in herds located in the 2007 outbreak area; month of service in 2005 for cows inseminated in 2005 in herds located in the 2007 outbreak area.</p><p>The unexposed population was composed of 211,578 cows in 9,485 herds, 2005–2007, France.</p

Return-to-service rates and distribution of cantons, herds and cows according to herds Bluetongue virus serotype 8 (BTV-8) exposure statuses, 2007, France.

<p>*Cows with first artificial insemination (AI) between 10 weeks before and 4 weeks after the observed date of clinical detection (case herds), the interpolated date of clinical detection (non-reported herds) and the transposed date in a year free of BTV-8 (herds in 2005 located in the 2007 outbreak area).</p><p>**Cows with first AI performed during the same period in the year than herds located in the outbreak area.</p

Binary and quantitative test responses for the PCR tests performed in bulk tank milk (PCR BTM) and indoor dust samples (PCR DUST) according to the stratified population.

<p>PCR BTM (n = 380) and PCR DUST (n = 380) tests were performed in 95 dairy cattle herds in the Finistère department, France between November 2012 and April 2014.</p