A quantum coherent spin in a two-dimensional material at room temperature

Quantum networks and sensing require solid-state spin-photon interfaces that combine single-photon generation and long-lived spin coherence with scalable device integration, ideally at ambient conditions. Despite rapid progress reported across several candidate systems, those possessing quantum coherent single spins at room temperature remain extremely rare. Here, we report quantum coherent control under ambient conditions of a single-photon emitting defect spin in a a two-dimensional material, hexagonal boron nitride. We identify that the carbon-related defect has a spin-triplet electronic ground-state manifold. We demonstrate that the spin coherence is governed predominantly by coupling to only a few proximal nuclei and is prolonged by decoupling protocols. Our results allow for a room-temperature spin qubit coupled to a multi-qubit quantum register or quantum sensor with nanoscale sample proximity

Hyperreflexivity and first-person perspective: a decisive contribution of contemporary phenomenological psychopathology to the understanding of schizophrenia

Objectives: This paper aims to summarize the hypothesis, which originates in the field of phenomenological psychopathology, of schizophrenic hyperreflexivity, and to discuss the methodological context enabling these highly subjective manifestations to emerge. Starting from the seminal hypothesis developed by contemporary psychopathology, that the schizophrenic patients appear to experience a consciousness that finds itself being forced to question phenomena which should be intuitively self-evident, the idea of this present paper is to complete the usual interpretation of schizophrenia as deficit by the hypothesis of an excess functioning of consciousness. Methods: First-person perspective is a qualitative approach completing third-person interpretation, traditional in the field of psychiatry – which consists in the attribution, from an external position, of clinical signs noted independently of the perception expressed by the patient. This first-person perspective focuses on the subjective experience expressed by the individual. To understand schizophrenia according to this perspective, the words of several schizophrenic patients have been collected as part of a clinical device. We used the EASE scale (Examination of Anomalous Self-Experience) with this aim in mind. This scale offers a phenomenologically oriented semi-structured exploration of a set of difficulties revealing anomalies of subjective experience, considered as troubles of self-awareness. EASE has been developed on the basis of self-descriptions by patients suffering from schizophrenic spectrum troubles. This tool allows the co-construction of a language between patient and clinician, focused on the patient’s particular experience and the unique phenomena he endures. Results: Besides the hyperreflexivity phenomena, the qualitative analysis of collected descriptions highlight two important features of schizophrenic being-in-the-world. First a problem of common sense, which addresses the issue of intersubjectivity and the opportunity, for schizophrenic patients, to share a social world. Then the existence of an intercorporeality trouble, since the schizophrenic hyperreflexivity experiences are accompanied by a loss of “common body”, body being the scene where intersubjectivity is performed. Employing EASE, and the ensuing first-person perspective, is relevant in a psychotherapeutic approach; on one hand in the process of acknowledgement of the disease (which has to be made by the patient as well as by the clinician), on the other hand in the communication with families of schizophrenic patients. Conclusions: The phenomenological interpretation offered by the application of a first-person perspective in the understanding of schizophrenic patients experience, as well as the interest showed in the hyperreflexivity phenomenon, suggest an outlook of schizophrenia which isn’t reduced to a deficit interpretation anymore (without denying the latter), and which uncovers not a weakening, but a surprising intensification of consciousness.Objectifs : Cet article présente l’hypothèse, issue du champ de la psychopathologie phénoménologique, de l’hyper-réflexivité schizophrénique, selon laquelle les patients schizophrènes sont pris dans l’expérimentation d’une conscience qui se retrouve contrainte d’interroger des phénomènes qui devraient aller intuitivement de soi. Méthodes : La perspective en première personne est une démarche qualitative complétant la lecture, traditionnelle dans le champ de la psychiatrie, en troisième personne – qui consiste en l’attribution depuis une position externe de signes cliniques repérés indépendamment du ressenti exprimé par le patient. Cette perspective en première personne concentre son attention sur l’expérience subjective qu’exprime le sujet. Le discours de plusieurs patients schizophrènes a été recueilli dans le cadre d’un dispositif clinique en utilisant l’échelle EASE (Examination of Anomalous Self-Experience). Cette échelle permet l’exploration semi-structurée, d’orientation phénoménologique, d’une série de difficultés révélatrices d’anomalies de l’expérience subjective. Résultats : En plus des phénomènes d’hyper-réflexivité, nos analyses mettent en évidence deux grandes caractéristiques de l’être-au-monde schizophrénique. D’abord une problématique du sens commun, qui pose la question de l’intersubjectivité. Ensuite l’existence d’un trouble de l’intercorporéité, les expériences d’hyper-réflexivité schizophrénique s’accompagnant d’une perte du « corps commun ». Conclusions : L’application d’une perspective en première personne dans la compréhension du vécu des patients schizophrènes, ainsi que l’intérêt porté au phénomène d’hyper-réflexivité, permettent de proposer une vision de la schizophrénie qui n’est plus réduite à une lecture déficitaire de celle-ci (sans nier cette dernière), et qui découvre non pas un affaiblissement, mais une intensification de la conscience

Hyper-réflexivité et perspective en première personne: Un apport décisif de la psychopathologie phénoménologique contemporaine à la compréhension de la schizophrénie

Objectives: This paper aims to summarize the hypothesis, which originates in the field of phenomenological psychopathology, of schizophrenic hyperreflexivity, and to discuss the methodological context enabling these highly subjective manifestations to emerge. Starting from the seminal hypothesis developed by contemporary psychopathology, that the schizophrenic patients appear to experience a consciousness that finds itself being forced to question phenomena which should be intuitively self-evident, the idea of this present paper is to complete the usual interpretation of schizophrenia as deficit by the hypothesis of an excess functioning of consciousness.Methods: First-person perspective is a qualitative approach completing third-person interpretation, traditional in the field of psychiatry – which consists in the attribution, from an external position, of clinical signs noted independently of the perception expressed by the patient. This first-person perspective focuses on the subjective experience expressed by the individual. To understand schizophrenia according to this perspective, the words of several schizophrenic patients have been collected as part of a clinical device. We used the EASE scale (Examination of Anomalous Self-Experience) with this aim in mind. This scale offers a phenomenologically oriented semi-structured exploration of a set of difficulties revealing anomalies of subjective experience, considered as troubles of self-awareness. EASE has been developed on the basis of self-descriptions by patients suffering from schizophrenic spectrum troubles. This tool allows the co-construction of a language between patient and clinician, focused on the patient’s particular experience and the unique phenomena he endures. Results: Besides the hyperreflexivity phenomena, the qualitative analysis of collected descriptions highlight two important features of schizophrenic being-in-the-world. First a problem of common sense, which addresses the issue of intersubjectivity and the opportunity, for schizophrenic patients, to share a social world. Then the existence of an intercorporeality trouble, since the schizophrenic hyperreflexivity experiences are accompanied by a loss of “common body”, body being the scene where intersubjectivity is performed. Discussion: Employing EASE, and the ensuing first-person perspective, is relevant in a psychotherapeutic approach; on one hand in the process of acknowledgement of the disease (which has to be made by the patient as well as by the clinician), on the other hand in the communication with families of schizophrenic patients. Conclusions: The phenomenological interpretation offered by the application of a first-person perspective in the understanding of schizophrenic patients experience, as well as the interest showed in the hyperreflexivity phenomenon, suggest an outlook of schizophrenia which isn’t reduced to a deficit interpretation anymore (without denying the latter), and which uncovers not a weakening, but a surprising intensification of consciousness.Objectifs :Cet article présente l’hypothèse, issue du champ de la psychopathologie phénoménologique, de l’hyper-réflexivité schizophrénique, selon laquelle les patients schizophrènes sont pris dans l’expérimentation d’une conscience qui se retrouve contrainte d’interroger des phénomènes qui devraient aller intuitivement de soi. Méthodes :La perspective en première personne est une démarche qualitative complétant la lecture, traditionnelle dans le champ de la psychiatrie, en troisième personne – qui consiste en l’attribution depuis une position externe de signes cliniques repérés indépendamment du ressenti exprimé par le patient. Cette perspective en première personne concentre son attention sur l’expérience subjective qu’exprime le sujet. Le discours de plusieurs patients schizophrènes a été recueilli dans le cadre d’un dispositif clinique en utilisant l’échelle EASE (Examination of Anomalous Self-Experience). Cette échelle permet l’exploration semi-structurée, d’orientation phénoménologique, d’une série de difficultés révélatrices d’anomalies de l’expérience subjective.Résultats :En plus des phénomènes d’hyper-réflexivité, nos analyses mettent en évidence deux grandes caractéristiques de l’être-au-monde schizophrénique. D’abord une problématique du sens commun, qui pose la question de l’intersubjectivité. Ensuite l’existence d’un trouble de l’intercorporéité, les expériences d’hyper-réflexivité schizophrénique s’accompagnant d’une perte du « corps commun ». Discussion :L’application d’une perspective en première personne dans la compréhension du vécu des patients schizophrènes, ainsi que l’intérêt porté au phénomène d’hyper-réflexivité, permettent de proposer une vision de la schizophrénie qui n’est plus réduite à une lecture déficitaire de celle-ci (sans nier cette dernière), et qui découvre non pas un affaiblissement, mais une intensification de la conscience.Conclusions :La prise en considération de la dimension tacite de l’existence schizophrénique, telle que le suggère la psychopathologie phénoménologique contemporaine, offre de précieuses informations à la pratique clinique et suggère d’importantes perspectives de recherche associant aux designs méthodologiques conventionnels des perspectives novatrices et prometteuses.info:eu-repo/semantics/publishe

Ex vivo experiments on femurs to assess metastatic bone strength

45e Congrès de la Société de Biomécanique, Metz, France, 26-/10/2020 - 28/10/2020Femoral fractures are a common issue for metastatic cancer patients. This type of fracture can occur during every day activities (Benca et al. 2017). Metastatic lesions can be osteoblastic, osteolytic or mixed but, mechanically, lytic lesions are more critical for the femoral strength (Benca et al. 2017). Based on a clinical scoring (Mirel's score), fracture predictions are overestimated and poorly predicted (Mirels 1989; Van der Linden et al. 2004; Benca et al. 2017), which leads to over-surgery. This scoring system is based on four following variables: metastases' site, size and type, and patient's pain (Mirels 1989). Hence, clinical studies do not focus on bone strength, but mainly on metastases characteristics and patient's pain. Finite element models, based on Quantitative Computed Tomography (QCT) imaging, were carried out to predict failure load (e.g., Kaneko et al. 2008; Tanck et al. 2009; Yosibash et al. 2014). In the context of metastatic bone, for a local validation, only one study has been published to study the major and minor principal strains using stereo-correlation (Sas et al. 2020) on cemented femur. The aim of this study was to provide experimental dataset to assess finite element models froma strain point of view

Bulletin épigraphique

Gauthier Philippe, Follet Simone, Sève Michel, Dubois Laurent, Mulliez Dominique, Cabanes Pierre, Helly Bruno, Hatzopoulos Miltiade, Brixhe Claude, Feissel Denis, Gatier Pierre-Louis, Bingen Jean, Dobias-Lalou Catherine. Bulletin épigraphique. In: Revue des Études Grecques, tome 110, Juillet-décembre 1997. pp. 484-617

Bulletin épigraphique

Dubois Laurent, Follet Simone, Sève Michel, Mulliez Dominique, Cabanes Pierre, Helly Bruno, Decourt Jean-Claude, Hatzopoulos Miltiade, Brixhe Claude, Feissel Denis, Gatier Pierre-Louis, Bingen Jean, Dobias-Lalou Catherine. Bulletin épigraphique. In: Revue des Études Grecques, tome 113, Juillet-décembre 2000. pp. 435-610

Bulletin épigraphique

Follet Simone, Sève Michel, Gauthier Philippe, Dubois Laurent, Mulliez Dominique, Cabanes Pierre, Helly Bruno, Decourt Jean-Claude, Hatzopoulos Miltiade, Brixhe Claude, Feissel Denis, Gatier Pierre-Louis, Bingen Jean, Dobias-Lalou Catherine. Bulletin épigraphique. In: Revue des Études Grecques, tome 112, Juillet-décembre 1999. pp. 568-714

Bulletin épigraphique

Gauthier Philippe, Follet Simone, Sève Michel, Masson Olivier, Dubois Laurent, Bousquet Jean, Helly Bruno, Cabanes Pierre, Hatzopoulos Miltiade, Brixhe Claude, Panayotou Anna, Feissel Denis, Gatier Pierre-Louis, Dobias-Lalou Catherine. Bulletin épigraphique. In: Revue des Études Grecques, tome 106, fascicule 506-508, Juillet-décembre 1993. pp. 460-588