Performance as indexed by RT in the Motor Task.

<p>Columns represent the MEAN and the bars the SEM (95% CI) for the RT in the Motor Task. Shifting: No shift represents the RT when the motor sequence remained the same (e.g., AA or BB), while Shift represents the RT when there were changes in the motor sequence set (e.g., AB or BA). tDCS: Represents the effects of polarity on performance. Site: Represents the estimates of the RT per site.</p

Schematic Representation of the experimental design used in this experiment.

<p>Schematic Representation of the experimental design used in this experiment.</p

Mean Number of errors and percentage of correct responses for the cognitive task.

<p>NS- No Shift Trial; S – Shift Trial. The values are means and the standard deviation is showed in brackets. On the left, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0024140#pone-0024140-t001" target="_blank">table 1</a> represents the total number of errors for the cognitive task. On the right, the percentage of correct responses to the same task is showed. Percentage of correct responses is included in order to provide a comparison between tasks.</p

Mean Number of errors and percentage of correct responses for the motor task.

<p>NS- No Shift Trial; S – Shift Trial. The values are means and the standard deviation is showed in brackets. On the left, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0024140#pone-0024140-t002" target="_blank">table 2</a> represents the total number of errors for the motor task. On the right, the percentage of correct responses to the same task is showed. Percentage of correct responses is included in order to provide a comparison between tasks.</p

Schematic Representation of the tasks used in the experiment.

<p>Each trial started with a next trial message on the center of the screen. Cognitive task: In this task, each trial consisted of a pair of stimulus. The set that the participant was required to respond could remain the same (e.g. Color S1 and Color S2) or could be different (e.g. Shape S1 and Color S2). Motor Task: In each trial a pair of letters appeared on screen (each letter represents a motor sequence of three key presses previous learned).</p

Performance as indexed by RT: Polarity and Site effects.

<p>Columns represent the MEAN and the bars the SEM for the RT (95% CI) in the Cognitive Task. tDCS: Represents the polarity effects in RT. Site: Represents the estimates of the RT per site of stimulation.</p

Results of pain thresholds: right hand.

<p>Pressure pain threshold levels before and after the tasks for the right untrained control hand. Ns = not significant.</p

Results of transcranial magnetic stimulation (TMS) measures.

<p>Values before and after the interventions are given as mean [± standard deviation]. MEP amplitude in mV; MEP integral in mV*ms; SICI and ICF in their index; CSP in ms. Student's t-test for pre/post-comparison. Statistical significance (p<0.05) indicated with asterisk *. Statistical trend (p<0.1) indicated with ∧ .</p><p>MEP: motor evoked potential; ICF: intracortical facilitation; SICI: short intracortical inhibition; CSP: cortical silent period; ML: motor learning; MA: motor activation; SD: standard deviation.</p

Results of pain thresholds: left hand.

<p>Pressure pain threshold levels before and after the tasks for the left trained hand. * = p<0.05. ** = p<0.01. *** = p<0.001.</p

Behavioral results of task ML_sighted.

<p>Lines indicate individual subjects' performance (number of traced words/shapes) over time. * = p<0.05. ** = p<0.01. *** = p<0.001.</p