The evaluating methodology of municipal management performance

© 2015 Canadian Center of Science and Education. All rights reserved. This article made an attempt to analyze the urban management according to the system approach (Mescon et al., 1988). The examination was fulfilled by the materials of social and economic development of single-industry city Naberezhnye Chelny (Shaykhraziev, 2014), that initially creates complicated conditions for the effective management (Fattakhova, 2011). There are some ways of improving urban management to the individual components of the system such as the operation factors "input", transformation entry-action, the assessment of services as an indicator of the "exit" of the system. The core message is the necessity to apply management sophisticated technologies to the local authority too, as they are used in the operation of enterprises and organizations (Fayolle et al., 1992)

Hypertrophic pachymeningitis: Current criteria for diagnosis and differentiation (Clinical case and review of literature)

The paper describes a 44-year-old male patient with an about 6-year history of hypertrophic pachymeningitis. The major clinical symptoms were characterized by headache, exophthalmos, and blindness in one eye. The data for differential diagnosis of the disease are given. The current literature on the clinical manifestations of hypertrophic pachymeningitis, its differential diagnosis, and the results of magnetic resonance imaging (MRI) is reviewed. Diagnostic difficulties at the stage of a clinical observation are due to the nonspecificity of neurological manifestations and the need for a comprehensive examination to detect a somatic disease. MRI can diagnose the disease-specific phenomenon of damage to the meninges, which calls for further careful differentiation. Clinicians must be familiar with alternative differential diagnosis, as a rapid specific therapeutic approach will help avoid long-term or irreversible neurological complications

An amperometric monoamine oxidase biosensor for determining some antidepressants

An amperometric biosensor based on a platinum screen-printed electrode and immobilized monoamine oxidase is developed to determine antidepressants of different classes. Petylyl, pyrazidol, and flu-oxetine can be determined with determination limits of 8 × 10-9, 8 × 10-7, and 8 × 10-10 M, respectively. A procedure is proposed for determining fluoxetine in tablets. It is shown that petylyl can be selectively determined by an immunochemical technique using the developed biosensor and immobilized antibodies in the concentration range from 1 × 10-4 to 1 × 10-8 M. © 2007 MAIK Nauka

Estimation of several antidepressants using an amperometric biosensor based on immobilized monoamine oxidase

An amperometric biosensor was developed on the basis of a printed platinum electrode and immobilized monoamine oxidase for detecting antidepressants of various classes. The analytical potential of the electrode was assessed: Petylyl (desipramine) and pyrazidol could be estimated from lower detection limits of 8 × 109 M for Petylyl and 8 × 107 M for pyrazidol. A method for estimating pyrazidol in tablets is described. © 2007 Springer Science+Business Media, Inc

Theoretical conformational analysis of cyclic organophosphorus and organosilicon compounds

The structure of some six- and eight-membered phosphorus and silicon heterocycles was established by the method of dipole moments and density functional theory calculations. There are two necessary conditions for the feasibility of the transannular interaction in these heterocycles: (1) the favorable disposition of the donor and acceptor centers in a molecule and (2) the presence of the substituents with the considerable polarizing effect at the heteroatom. Copyright © Taylor & Francis Group, LLC

Experimental and theoretical conformational analysis of methylene- and cyanophosphines and their oxides

The structure of a great number of methylenephosphine oxides 1-11 and cyanophosphines and their oxides 12-18 was studied by semiempirical PM3 and ab initio RHF/6-31G** calculations. Obtained results are in good agreement with experimental data (dipole moments, Kerr effect, IR spectroscopy). In 12-18 the contribution of interactions of CN group or Ph ring with lone pair of electrons (LPE) of the P atom, d-orbitals of the P atom, or P=O group is absent

FUNCTIONAL COMPOSITE MATERIAL BASED ON MOLYBDENUM OXIDE

Предложен эффективный гидротермально-микроволновой метод синтеза композита на основе триоксида молибдена и углерода (МоО3/С). Фазовый состав композита был исследован с помощью рентгенофазового анализа (РФА). Морфология, размер частиц полученных материалов определены на сканирующей электронной микроскопии (СЭМ). Наличие углерода в композите подтверждено термогравиметрическим анализом, совмещенным с масс-спектроскопией (ТГ–МС–ДСК) и КР-спектроскопией. Площадь удельной поверхности, преимущественный размер пор образцов были изучены методом низкотемпературной адсорбции азота (БЭТ).An effective hydrothermal-microwave method for the synthesis of a composite based on molybdenum trioxide and carbon (MoO3/C) has been proposed. The phase composition of the compound was investigated using X-ray phase analysis (XRD). The morphology and particle size of the as-prepared materials have been determined by scanning electron microscopy (SEM). The presence of carbon in the composite was confirmed using a thermogravimetric analysis combined with mass spectroscopy (TG–MS–DSC) and Raman spectroscopy. The specific surface area, the predominant pore size of the samples were studied by the low-temperature nitrogen adsorption method (BET).Работа выполнена при финансовой поддержке РФФИ-ГФЕН Китая (проект № 16-53-53069)

Assay of nitrofuran drugs using an amperometric monoamine oxidase biosensor

A method for assaying nitrofuran drugs (furazolidone, furadonine, and furagin) using an amperometric biosensor based on a printed platinum electrode and immobilized monoamine oxidase was developed for analysis of medicinal formulations and urine. Nitrofuran derivatives were found to have inhibitory actions, albeit weaker than those of classical tricyclic antidepressants, on the catalytic activity of monoamine oxidase. This side-effect inhibitory action allowed assay of furazolidone, furadonine, and furagin with lower detection limits, which were 8.3 × 10-9, 8.5 × 10-8, and 9.4 × 10-10 M respectively. The results obtained here show that this side effect of furazolidone, furadonine, and furagin must be taken into consideration when these agents are prescribed to patients. © 2011 Springer Science+Business Media, Inc

Determination of Antidepressants Using Monoamine Oxidase Amperometric Biosensors Based on Screen-Printed Graphite Electrodes Modified with Multi-Walled Carbon Nanotubes

© 2014, Springer Science+Business Media New York. Novel amperometric biosensors based on screen-printed graphite electrodes modified with multi-walled carbon nanotubes (MWCNTs) dispersed in various solvents (chitosan, DMF) and immobilized monoamine oxidase (MAO) were developed for the determination of the antidepressants imipramine and afobazole. It was found that afobazole and imipramine inhibited MAO, which allowed these pharmaceuticals to be determined within the concentration range from 0.1 mM to 1 nM by recording the H2O2 oxidation wave when dopamine and epinephrine were used as MAO substrates. The best analytical performance was observed for MAO biosensors modified by MWCNTs in chitosan solution, for which the lower detection limit was 3 – 9 nM. The main active ingredients in melipramine and afobazole preparations were quantified with an RSD of 0.08 using the MAO-based amperometric biosensors