Perancangan Game Puzzle Untuk Pembelajaran Menggunakan Metodologi Multimedia

Game edukasi merupakan sebuah permainan yang dikemas dalam konteks pendidikanuntuk merangsang daya pikir dan termasuk salah satu cara untuk melatih meningkatkan konsentrasipenggunanya (anak-anak). Penelitian ini bertujuan untuk merancang game puzzle sebagai mediapembelajaran untuk meningkatkan semangat belajar dan sosial pada anak sekolah dasar. Game puzzleini dirancang menggunakan metode multimedia Luther Sutopo. Metode multimedia luther sutopo initerdiri dari beberapa tahapan yaitu concept, design, material collecting, assembly, testing, dandistribution. Hasil dari penelitian ini berupa game puzzle dengan menggunakan adobe flash CS6sebagai aplikasi pembangunnya, aplikasi yang telah dihasilkan dapat digunakan untuk membantuproses belajar mengajar dan juga dapat meningkatkan semangat belajar serta sosial pada anak sekolahdasar, untuk selanjutnya diharapkan aplikasi yang dibuat dapat dikembangkan lagi untuk digunakansesuai dengan kebutuhannya

Detection of Human Papillomavirus, p53 and c-erbB-2 Protein Expression in Juvenile Laryngeal Papillomatosis: A Report of 2 Cases

The association of human papillomavirus (HPV) with juvenile laryngeal papillomatosis has been well documented. We report two cases of juvenile laryngeal papillomatosis and correlated these cases with presence of HPV, p53 and c-erbB-2 proteins. The first case was a one-year-old male patient and the second a six-year-old female patient. Formalin-fixed paraffin-embedded biopsy specimens were tested for the presence of HPV genome by the technique of in situ hybridisation using wide spectrum and type specific biotinylated probes while the immunohistochemical expression of p53 (D07, 1:50) and c-erbB-2 (DAKO A0485, 1:300) proteins were evaluated with commercially available antibodies. Histologically the tumours in both cases showed papillary configuration of squamous papilloma. The first case detected HPV type 6, HPV type 11 and p53 protein expression while the second case showed only HPV type 6. Both cases of HPV showed positive signals confined to the nuclei in the superficial squamous epithelium. The first case showed p53 positivity seen from the basal region up to one third of the epithelium of laryngeal papillomas and the subsequent recent repeat biopsy showed the positivity of p53 had extended throughout the upper layers of the epithelium. Expression of c-erbB-2 protein was not detected in both cases. These findings were similar as in other studies where follow-up of the cases was recommended since they tend to recu

Online logistics booking system utilizing artificial intelligence

In this paper, the application of genetic algorithm (GA) in linear and non-linear dynamic modeling, as well as the development of an alternative GA-based model structure selection algorithm is presented. As a benchmark for the proposed algorithm, orthogonal least square (OLS), a gradient descent method, is utilized. To reduce problems of premature convergence in simple GA (SGA), a model structure selection based on modified genetic algorithm (MGA) is proposed. The effect of different combinations of MGA operators on the performance of the developed model was studied, and the effectiveness and shortcomings of MGA were highlighted. Results were compared between SGA, MGA, and OLS. From the results obtained, it was observed that with similar number of dynamic terms, MGA performs better than SGA, in terms of exploring potential solution, meanwhile outperformed the OLS algorithm in terms of selected number of terms and predictive accuracy. In addition, for fine-tuning, the use of local search of memetic algorithm (MA) with MGA is also proposed and investigated. From the results obtained, it can be observed that MA can produce an adequate which satisfy the model validation tests with significant advantages over OLS, SGA, and MGA methods

Abstracts of the International Halal Science Conference 2023

This book presents the extended abstracts of the selected contributions to the International Halal Science Conference, held on 22-23 August 2023 by the International Institute for Halal Research and Training (INHART), IIUM, Malaysia in collaboration with Halalan Thayyiban Research Centre, University Islam Sultan Sharif (UNISSA), Brunei Darussalam. With the increasing global interest in halal products and services, this conference is timely. Conference Title:  International Halal Science ConferenceConference Acronym: IHASC23Conference Theme: Halal Industry Sustainability Through ScienceConference Date: 22-23 August 2023Conference Venue: International Islamic University (IIUM), MalaysiaConference Organizer: International Institute for Halal Research and Training (INHART), International Islamic University (IIUM), Malaysi