Depression in Frail Older Adults: Associations and Gender Difference

OBJECTIVE. Depression is highly prevalent in frail older adults and both clinical situations share similar clinical and prognostic factors. The aim of this study was to investigate the relationship between frailty and depression by considering each component of frailty, in both genders

Relationship Between Dysphagia and Sarcopenia with Comprehensive Geriatric Evaluation

Oropharyngeal dysphagia has features of geriatric syndromes and is strongly associated with sarcopenia. In this cross-sectional study, we aimed to evaluate the association between dysphagia and sarcopenia, in a practical way, accompanied by comprehensive geriatric assessment. Dysphagia and sarcopenia were defined by the EAT-10 and SARC-F questionnaires, respectively. Cognition and mood, was evaluated by the Mini-mental State Examination (MMSE) and Geriatric Depression Scale (GDS), respectively. Physical performance was assessed by the Timed up and Go Test (TUG) and muscle strength was determined by Hand Grip Strength (HGS). Functionality was stated by Katz and Lawton Indexes. Serum levels of hemoglobin, triglyceride, albumin, and total cholesterol were recorded. A total of 512 (151 male/361 female) patients age 60 and older were included in the study. Prevalences of dysphagia and sarcopenia were 23% and 40.6%, respectively. In multivariate analysis sarcopenia (OR:2.596, p = 0.008), depressive symptoms (OR:1.115, p < 0.001), and lower KATZ scores (OR:0.810, p = 0.036) were independently related with dysphagia. Dysphagic patients with sarcopenia had lower scores on the Katz and Lawton scales (p < 0.001, r(pb) = 0.380 and p < 0.001, r(pb) = 0.447 respectively) and TUG performances were worse (p = 0.009, r(pb) = - 0.254). Serum hemoglobin and albumin levels were significantly low in dysphagic patients with sarcopenia (p < 0.001, r(pb) = 0.345, p = 0.008, r(pb) = 0.243). Dysphagia is independently associated with sarcopenia, depressive symptoms, and functionality. Dysphagia coexist with sarcopenia is associated with worse clinical consequences than without sarcopenia

Frailty in Patients with Parkinson's Disease: Associations with Disability and Timed Up and Go

Introduction: Aim of this study was identify the prevalence of frailty in patients with idiopathic Parkinson's disease (PD), to describe the relationship between severity of the disease and frailty, and to evaluate if timed up and go (TUG) is an eligible test for determination of frailty in idiopathic PD patients

The impact of sleep duration on frailty in community-dwelling Turkish older adults

© 2020, Japanese Society of Sleep Research.The aim of this study was to examine the association between sleep duration and frailty in community-dwelling Turkish older adults and to determine whether this association varies depending on gender. A cross-sectional study was conducted from August 2013 to December 2013 with 905 individuals, representative of the aged population ≥ 60 years in community-dwelling elderly. Self-reported sleep duration was classified as short sleep duration (≤ 6 h), middle sleep duration (6.1–8.9 h), and long sleep duration (≥ 9 h). Frailty was assessed according to the FRAIL scale (FRAIL: Fatigue, Resistance, Ambulation, Illness, Low weight).The study included 905 community-dwelling older adults (447 male and 458 female). The median (25p–75p) age of the study population was 71.0 years (67.0–75.0) (range 60–92 years). The number of patients according to the short, middle, and long sleep durations were 120 (13.3%), 341 (37.7%), and 433 (47.8%), respectively. The median duration of sleep time in the total study population was 8.5 (7.0–10.0) h. According to frailty status, the percent of robust subjects was higher in the group with mid sleep duration than the other two groups (p = 0.020). Short sleep duration was associated with frailty in the female gender in both the unadjusted model (OR 2.80, 95% CI 1.42–5.52) and the fully adjusted model (OR 3.42, 95% CI 1.50–7.77). Short sleep duration is independently associated with frailty in community-dwelling Turkish female older adults, thus frailty prevention interventions should consider sleep duration in females