8 research outputs found

    Deciding a multicriteria decision-making (Mcdm) method to prioritize maintenance work orders of hydroelectric power plants

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    The current global competitive scenario and the increase in complexity and automation of equipment and systems demand better results from maintenance management in organizations. As maintenance resources are limited, prioritizing maintenance activities is essential to allocate them properly and to meet maintenance management objectives. In the face of these challenges, multicriteria decision-making (MCDM) methods are commonly used in organizations to support decision-making. Nevertheless, selecting a suitable MCDM method for maintenance planning can be complicated given the diversity of methods and their strengths and weaknesses. In this context, this paper proposes a novel knowledge-based method for deciding a multicriteria decision-making (MCDM) method to prioritize maintenance work orders of hydroelectric plants. As the main novel contribution, it translates the intrinsic characteristics of the main MCDM methods into questions related to maintenance planning to guide the recommendation of a suitable MCDM method for organizations through a decision tree diagram. This approach was applied to a maintenance case study of a hydroelectric power plant in order to demonstrate its use and contribute to its understanding. These findings contribute to maintenance management in selecting an MCDM method aligned with the context of its maintenance planning for the prioritization of maintenance work orders

    ORGANIZATION OF ALPHA-GLOBIN GENES AND MESSENGER-RNA TRANSLATION IN SUBJECTS CARRYING HEMOGLOBIN HASHARON (ALPHA-47 ASP -] HIS) FROM THE FERRARA REGION (NORTHERN ITALY)

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    In subjects carrying the haemoglobin Hasharon mutation (alpha 47 replaced by His), originally from the delta of the Po river (Northern Italy), the concentration of the alpha-globin variant has been evaluated and found to be approximately 32%, a value definitely higher than that reported for the same mutant haemoglobin in other regions. Restriction enzyme analysis has been carried out on the DNA from these subjects; the data obtained indicate the presence of three alpha-globin genes per diploid cell. Family studies further show that the two normal genes are located on one chromosome and the Hasharon gene on the other. The origin of the single alpha-gene in the Hasharon-carrying subjects of the Ferrara region is discussed in connection with their haematological and biosynthetic data
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