22,317 research outputs found

    Device for suppressing sound and heat produced by high-velocity exhaust jets Patent

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    Device for adding water to high velocity exhaust jets to reduce velocity, noise, and temperatur

    Predicted acoustical performance of the S-IC SOUND suppressor

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    Scale model acoustical tests for predicting performance of S-IC static test facility sound suppresso

    Consequences of Postnatally Elevated Insulin-Like Growth Factor-II in Transgenic Mice: Endocrine Changes and Effects on Body and Organ Growth.

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    Insulin-like growth factor-II (IGF-II) is an important regulator of embryonic growth and differentiation, but its function in postnatal life is unclear. To address this point, we generated transgenic mice harboring fusion genes in which a human IGF-II complementary DNA is placed under the transcriptional control of the rat phosphoenolpyruvate carboxykinase promoter. Transgene-specific messenger RNA was detected in liver, kidney, and several parts of the gut. Serum IGF-II levels in transgenic mice were 2-3 times higher than those in controls and increased after starvation. Circulating IGF-I correlated negatively and IGF-binding protein-2 (IGFBP-2) positively with IGF-II levels, suggesting that IGF-I is displaced from IGFBPs by IGF-II and that IGFII is a major regulator of IGFBP-2. Serum levels of IGFBP-3 and IGFBP-4 tended to be higher in phosphoenolpyruvate carboxykinase- IGF-II transgenic mice than in controls, as evaluated by ligand blot analysis. Starvation reduced serum IGF-I, but increased IGFBP-2 in transgenic mice more markedly than in controls. Fasting insulin levels were significantly reduced in transgenic mice, whereas glucose levels were not influenced by elevated IGF-II. The body growth of 4- and 12- week-old mice was not significantly influenced by elevated IGF-II, but transgenic mice displayed increased kidney and testis weight at the age of 4 weeks, and increased adrenal weight at the age of 12 weeks. Our results demonstrate that elevated IGF-II in postnatal life has multiple endocrine consequences and subtle time-specific effects on organ growth

    Negative differential conductance induced by spin-charge separation

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    Spin-charge states of correlated electrons in a one-dimensional quantum dot attached to interacting leads are studied in the non-linear transport regime. With non-symmetric tunnel barriers, regions of negative differential conductance induced by spin-charge separation are found. They are due to a correlation-induced trapping of higher-spin states without magnetic field, and associated with a strong increase in the fluctuations of the electron spin.Comment: REVTEX, 4 pages including 3 figures; Accepted for publication on Physical Review Letter

    Localized low-frequency Neumann modes in 2d-systems with rough boundaries

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    We compute the relative localization volumes of the vibrational eigenmodes in two-dimensional systems with a regular body but irregular boundaries under Dirichlet and under Neumann boundary conditions. We find that localized states are rare under Dirichlet boundary conditions but very common in the Neumann case. In order to explain this difference, we utilize the fact that under Neumann conditions the integral of the amplitudes, carried out over the whole system area is zero. We discuss, how this condition leads to many localized states in the low-frequency regime and show by numerical simulations, how the number of the localized states and their localization volumes vary with the boundary roughness.Comment: 7 pages, 4 figure
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