How do Europeans quit using tobacco, e-cigarettes and heated tobacco products? A cross-sectional analysis in 28 European countries

Objectives: While smoking tobacco remains a substantial cause of harm in Europe, novel products such as electronic cigarettes or e-cigarettes (ECs) and heated tobacco products (HTPs) have entered the market recently. While debate still persists over the role of these novel products, they are now in widespread use. This study aimed to explore the prevalence and methods of attempts to quit EC and HTP. Setting: We analysed the 2020 Eurobarometer survey, which collected data in 28 European countries. Participants: A representative sample of individuals residing in these countries aged ≥15 years. Primary and secondary: outcome measures Multilevel regression analyses were performed to assess differences in quit attempts and cessation methods among tobacco smokers and exclusive EC/HTP users separately. Results: 51.1% of current tobacco smokers and 27.1% of exclusive EC or HTP users reported having ever made a quit attempt. The majority of former and current smokers (75.8%) who made a quit attempt did so unassisted, with 28.8% reporting at least one attempt using a cessation aid. The most popular cessation aids were nicotine replacement therapy or other medication (13.4%) and ECs (11.3%). 58.8% of exclusive EC or HTP users who had made a quit attempt did so unassisted, with 39.5% reporting the use of a cessation aid. Conclusion: Most EC and HTP users in Europe try to quit unassisted, although more of them report the use of a cessation aid compared with tobacco smokers. Cessation support services should take into consideration the increasing numbers of users of EC and HTP who may be trying to quit

Efficacy of a new single-pill combination of a thiazide-like diuretic and a calcium channel blocker (indapamide sustained release/amlodipine) in essential hypertension

Objectives: The current international, 12-week, double-blind, randomized, controlled trial assessed the efficacy and safety of indapamide sustained release/amlodipine single-pill combination (SPC) in mild-to-moderate hypertensive patients. Methods: Following a 4-week run-in period on amlodipine 5 mg, patients (SBP 150–180 mmHg and/or DBP < 110 mmHg) were randomized to indapamide 1.5 mg sustained release/amlodipine 5 mg SPC or amlodipine 5 mg/valsartan 80 mg SPC with conditional uptitration at week 6. Office blood pressure (BP) was assessed at baseline, weeks 6 and 12; ambulatory and home blood pressure monitoring (ABPM/HBPM) at baseline and week 12. Results: Baseline characteristics were similar in both groups (57 years, 51% men, BP 160/92 mmHg). 233 patients were randomized to IndSR/Aml and 232 to amlodipine/valsartan, of whom 48 and 57% were uptitrated, respectively. After 12 weeks, office SBP/DBP decreased similarly with both treatments (−21/−8 vs. −20/−8 mmHg) leading to BP control in 50% and BP response in 70% of patients. Uptitration was effective (P < 0.001) with both regimens, in favour of IndSR/Aml (SBP/DBP −12/−6 vs. −7/−3 mmHg, respectively). ABPM (n = 273) and HBPM (n = 194) confirmed 24-h efficacy of both regimens. In the subgroup of patients with sustained uncontrolled hypertension assessed by ABPM (n = 216), office SBP/DBP decreased by −23/−13 vs. −18/−10 mmHg, respectively (P = 0.016/P = 0.135, post-hoc analysis). Both treatments were generally well tolerated. Conclusion: Both regimens produced effective BP reductions confirmed by ABPM/HBPM. Both treatments were well tolerated, in accordance with the individual agents’ safety profile. Trial registration number: EUDRA CT no. 2012-001690-84

La influencia de la autoridad formal y el estilo de enseñanza del delegado en el disfrute de los estudiantes en la asignatura de estudios empresariales

The purpose of this study was to examine the teacher’s teaching style and students’ attitude towards the business studies subject. The samples were 189 upper six students who took business studies subject. This study used the survey method. Descriptive and inferential statistics used were Pearson correlations. The study found that the personal model teaching style was the preferred teaching style.  Students’ attitude towards the business studies subject was at a moderate level. Correlation analysis revealed a significant positive relationship between teachers’ teaching style and students’ attitude toward business studies subject. The results of Pearson’s correlation test found that two types of teaching styles that were formal authority and delegator style had a significant relationship with the sub-constructs of attitude namely enjoyment.El propósito de este estudio fue examinar el estilo de enseñanza del maestro y la actitud de los estudiantes hacia la asignatura de estudios de negocios. Las muestras fueron 189 estudiantes de los seis primeros que tomaron asignaturas de estudios empresariales. Este estudio utilizó el método de encuesta. Las estadísticas descriptivas e inferenciales utilizadas fueron las correlaciones de Pearson. El estudio encontró que el estilo de enseñanza modelo personal era el estilo de enseñanza preferido. La actitud de los estudiantes hacia la asignatura de estudios empresariales fue moderada. El análisis de correlación reveló una relación positiva significativa entre el estilo de enseñanza de los maestros y la actitud de los estudiantes hacia la asignatura de estudios empresariales. Los resultados de la prueba de correlación de Pearson encontraron que dos tipos de estilos de enseñanza que eran autoridad formal y estilo delegador tenían una relación significativa con las subconstrucciones de actitud, a saber, el disfrute

Geographical Analysis of Agro-Environmental Measures for Reduction of Chemical Inputs in Tuscany

The agro-environmental policies included in rural development plans are getting increasing importance in European Community strategies. These policies represent the meeting point between demand and supply of positive externalities. The difficulty of assessing real envi- ronmental efficiency is one of the elements characterizing agro-environmental measures. This difficulty is related to the identification of suitable parameters for evaluating farms according to their impact on the territory. This impact is mainly related both to chemical inputs and to the territorial characteristics of the farm. Different types of fertilizers, pesti- cides and herbicides are currently used in production processes; however, the analysis has focused only on nitrates, as they represent the most critical types of chemicals related to soil pollution. A case study is provided by analysis of agro-environmental measures in Tuscany for the reduction of nitrates in organic and integrated farms. Using spatial multicriteria analysis, integrated and organic farms were classified according to their geographical loca- tions and their release of nitrates into the soil. This classification permits the highlighting of farms that make the greatest economic efforts to reduce pollution and therefore it could determine environmental benefits. Considering that the trend of policy strategies is toward a reduction of monetary resources, the classification could help decision makers choose the right allocation of future resources

On the Response of an OST to a Point-like Heat Source

A new technique of superconducting cavity diagnostics has been introduced by D. Hartrill at Cornell University, Ithaca, USA. Oscillating Superleak Transducers (OST) detect the heat transferred from a cavity's quench point via "Second Sound" through the superfluid He bath, needed to cool the superconducting cavity. The observed response of an OST is a complex, but reproducible pattern of oscillations. A small helium evaporation cryostat was built which allows the investigation of the response of an OST in greater detail. The distance between a point-like electrical heater and the OST can be varied. The OST can be mounted either parallel or perpendicular to the plate, housing the heat source. If the artificial quench-point releases an amount of energy compatible to a real quench spot on a cavity's surface, the OST signal starts with a negative pulse, which is usually strong enough to allow automatic detection. Furthermore, the reflection of the Second Sound on the wall is observed. A reflection coefficient R = 0.39 +- 0.05 of the glass wall is measured. This excludes a strong influence of multiple reflections in the complex OST response. Fourier analyses show three main frequencies, found in all OST spectra. They can be interpreted as modes of an oscillating circular membrane.Comment: 10 pages, 16 figure

Bright microwave pulses from PSR B0531+21 observed with a prototype transient survey receiver

Recent discoveries of transient radio events have renewed interest in time-variable astrophysical phenomena. Many radio transient events are rare, requiring long observing times for reliable statistical study. The National Aeronautics and Space Administration/Jet Propulsion Laboratory\u27s Deep Space Network (DSN) tracks spacecraft nearly continuously with 13 large-aperture, low system temperature radio antennas. During normal spacecraft operations, the DSN processes only a small fraction of the pre-detection bandwidth available from these antennas; any information in the remaining bandwidth, e.g., from an astronomical source in the same antenna beam as the spacecraft, is currently ignored. As a firmware modification to the standard DSN tracking receiver, we built a prototype receiver that could be used for astronomical transient surveys. Here, we demonstrate the receiver\u27s utility through observations of bright pulses from the Crab pulsar and describe attributes of potential transient survey observations piggybacking on operational DSN tracks. © 2014. The American Astronomical Society. All rights reserved.