65 research outputs found

    Macular pigment Raman detector for clinical applications

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    Journal ArticleClinical studies of carotenoid macular pigments (MP) have been limited by the lack of noninvasive, objective instruments. We introduce a novel noninvasive optical instrument, an MP Raman detector, for assessment of the carotenoid status of the human retina in vivo. The instrument uses resonant excitation of carotenoid molecules in the visible wavelength range, and quantitatively measures the highly specific Raman signals that originate from the single- and double-bond stretch vibrations of the pi-conjugated carotenoid molecule's carbon backbone. The instrument is a robust, compact device and suitable for routine measurements of MP concentrations in a clinical setting. We characterized and tested the instrument in clinical studies of human subjects to validate its function and to begin to establish its role as a possible screening test for macular pathologies. We also show that the MP Raman spectroscopy technology has potential as a novel, highly specific method for rapid screening of carotenoid antioxidant levels in large populations at risk for vision loss from age-related macular degeneration, the leading cause of blindness of the elderly in the developed world

    Testing eigenstate decoherence hypothesis in a model of collisional decoherence

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    The eigenstate decoherence hypothesis (EDH) asserts that each individual eigenstate of a large closed system is locally classical-like. We test this hypothesis for a heavy particle interacting with a gas of light particles. This system is paradigmatic for studies of the quantum-to-classical transition: The reduced state of the heavy particle is widely believed to rapidly loose any nonclassical features due to the interaction with the gas. Yet, we find numerical evidence that the EDH is violated: certain eigenstates of this model are manifestly non-classical. Only the weak version of EDH referring to the majority (instead of the totality) of eigenstates holds

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    Бибирский Ρ‰ΠΈΡ‚ ВолТской Ρ‚Π²Π΅Ρ€Π΄Ρ‹Π½ΠΈ

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    On the fundamental work β€œThe Siberian Shield of the Volga Stronghold”, telling about the contribution of the Siberians and the Far-Easterns to the defeat of Nazi invaders and their Hungarian, Romanian, Italian satellites and the Spanish β€œBlue Division” on the banks of Volga, the Great Russian River.О Ρ„ΡƒΠ½Π΄Π°ΠΌΠ΅Π½Ρ‚Π°Π»ΡŒΠ½ΠΎΠΌ Ρ‚Ρ€ΡƒΠ΄Π΅ «Бибирский Ρ‰ΠΈΡ‚ ВолТской Ρ‚Π²Π΅Ρ€Π΄Ρ‹Π½ΠΈΒ», ΠΏΠΎΠ²Π΅ΡΡ‚Π²ΡƒΡŽΡ‰Π΅ΠΌ ΠΎ Π²ΠΊΠ»Π°Π΄Π΅ сибиряков ΠΈ Π΄Π°Π»ΡŒΠ½Π΅Π²ΠΎΡΡ‚ΠΎΡ‡Π½ΠΈΠΊΠΎΠ² Π² Ρ€Π°Π·Π³Ρ€ΠΎΠΌ гитлСровских Π·Π°Ρ…Π²Π°Ρ‚Ρ‡ΠΈΠΊΠΎΠ² ΠΈ ΠΈΡ… вСнгСрских, румынских, ΠΈΡ‚Π°Π»ΡŒΡΠ½ΡΠΊΠΈΡ… сатСллитов ΠΈ испанской Β«Π“ΠΎΠ»ΡƒΠ±ΠΎΠΉ Π΄ΠΈΠ²ΠΈΠ·ΠΈΠΈΒ» Π½Π° Π±Π΅Ρ€Π΅Π³Π°Ρ… Π²Π΅Π»ΠΈΠΊΠΎΠΉ русской Ρ€Π΅ΠΊΠΈ Π’ΠΎΠ»Π³ΠΈ

    Бибиряки - Π·Π°Ρ‰ΠΈΡ‚Π½ΠΈΠΊΠΈ ΠΈ ΠΏΠΎΠ±Π΅Π΄ΠΈΡ‚Π΅Π»ΠΈ

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    Review of publication "Siberians in the battle for Moscow", which is part of the anthology "Tobolsk, and the whole of Siberia", published by the Public Charitable Foundation "Revival of Tobolsk."ΠžΠ±Π·ΠΎΡ€ издания «Бибиряки Π² Π±ΠΈΡ‚Π²Π΅ Π·Π° ΠœΠΎΡΠΊΠ²ΡƒΒ», входящСго Π² состав Π°Π»ΡŒΠΌΠ°Π½Π°Ρ…Π° «Вобольск ΠΈ вся Π‘ΠΈΠ±ΠΈΡ€ΡŒΒ», Π²Ρ‹ΠΏΡƒΡ‰Π΅Π½Π½ΠΎΠ³ΠΎ ΠžΠ±Ρ‰Π΅ΡΡ‚Π²Π΅Π½Π½Ρ‹ΠΌ Π±Π»Π°Π³ΠΎΡ‚Π²ΠΎΡ€ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹ΠΌ Ρ„ΠΎΠ½Π΄ΠΎΠΌ Β«Π’ΠΎΠ·Ρ€ΠΎΠΆΠ΄Π΅Π½ΠΈΠ΅ Вобольска»
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