222 research outputs found

    MT SCORP: Public Recreational Use Study 2012

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    The purpose of the Public Recreational Use Survey was to understand the current outdoor recreation facility uses by Montana residents

    MT SCORP: Facility and Natural Resource Recreation Area Needs: Facility Manager Responses 2012

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    A survey of local, state, federal, school and tribal mangers were surveyed to understand the quantity and quality of outdoor recreation facilities and area needs. This study was conducted for use in the State Comprehensive Outdoor Recreation Plan process

    MT SCORP: Resident Travel for Outdoor Recreation in Montana

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    The purpose of this analysis was to understand the resident travel patterns of Montanans who participate in outdoor recreation. This was a secondary data analysis from data collected by the Institute for Tourism and Recreation Research (ITRR) from their most recent resident travel study conducted in 2011-2012 for one year

    Nonresident Values of Montana\u27s Natural Areas

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    Three quarters of nonresident vacationers to Montana are primarily attracted to characteristics of public lands such as national parks, mountains, forests, and open space. Viewing and recreating on Montana\u27s public lands are vitally important to the success of the travel industry in the state. Therefore, the purpose of this study was to assess public land values held by nonresident visitors to Montana and to compare values between groups of outdoor recreation participants

    MT SCORP: Behavioral Risk Factor Surveillance System: Outdoor Recreation and Resident Health

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    The Behavioral Risk Factor Surveillance System (BRFSS) provides state-based data on health and risk behaviors among adults. Several supplemental outdoor recreation related questions were included in the 2011 questionnaire to assist with the State Comprehensive Outdoor Recreation Plan process and are analyzed in this report

    Ionic Liquids in Multiphase Systems

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    Ionic liquids (ILs) can be used to replace one or more phases in conventional oil/water emulsions including Pickering emulsions—surfactant-free emulsions which utilize nano- or micron-sized particles to stabilize the immiscible liquid-liquid interface. Due to the extreme tunability of both the ILs and particles used, the study of IL-based Pickering emulsions yields novel emulsion morphologies and insights into the ionic liquid-liquid-particle interactions present. This work discusses extensive experimental work on IL-based Pickering emulsions and IL/liquid interfaces, emphasizing unique phenomena—such as “bridging” between emulsion droplets and spontaneous particle transport across the interface—never observed in more conventional Pickering emulsions. Molecular dynamics (MD) simulations of particles at the IL/liquid interface are also discussed, and fundamental insights from these simulations are used to enhance understanding of the unique interface behavior revealed by experiment

    Picture This: Developing a Model for the Analysis of Visual Metadiscourse

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    © The Author(s) 2015. Corporate documents increasingly rely on visual rhetoric to complement text. Although previous studies have indicated that companies’ local culture may be reflected in the images they employ, scholars have never systematically investigated the use of visual rhetoric as it is used across different business cultures. This study analyzes visual rhetoric using a new model of visual metadiscourse—a set of devices that designers use to convey meaning in order to influence the audience’s interpretation of the text. The study compares the visual metadiscourse in photos used in English management statements in the annual reports of Dutch and U.K. companies. The results show that metadiscourse is inherent not only in the written text of a corporate document but also in the visuals that a design team chooses to include. The results also indicate that despite some similarities, Dutch-based and U.K.-based statements contain differences in their use of visual metadiscourse. Several of these differences can be attributed to cultural differences between the Netherlands and the United Kingdom. The study underlines the applicability of the new model and warns international text designers not to overlook cultural differences in visual metadiscourse

    A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance

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    In eutherians, the placenta acts as a barrier and conduit at the maternal-fetal interface. Syncytiotrophoblasts, the multinucleated cells that cover the placental villous tree surfaces of the human placenta, are directly bathed in maternal blood and are formed by the fusion of progenitor cytotrophoblasts that underlie them. Despite their crucial role in fetal protection, many of the events that govern trophoblast fusion and protection from microbial infection are unknown. We describe a three-dimensional (3D)–based culture model using human JEG-3 trophoblast cells that develop syncytiotrophoblast phenotypes when cocultured with human microvascular endothelial cells. JEG-3 cells cultured in this system exhibit enhanced fusogenic activity and morphological and secretory activities strikingly similar to those of primary human syncytiotrophoblasts. RNASeq analyses extend the observed functional similarities to the transcriptome, where we observed significant overlap between syncytiotrophoblast-specific genes and 3D JEG-3 cultures. Furthermore, JEG-3 cells cultured in 3D are resistant to infection by viruses and Toxoplasma gondii, which mimics the high resistance of syncytiotrophoblasts to microbial infections in vivo. Given that this system is genetically manipulatable, it provides a new platform to dissect the mechanisms involved in syncytiotrophoblast development and microbial resistance

    Colorectal polyp outcomes after participation in the seAFOod polyp prevention trial: Evidence of rebound elevated colorectal polyp risk after short-term aspirin use

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    BACKGROUND: The seAFOod polyp prevention trial was a randomised, placebo-controlled, 2 × 2 factorial trial of aspirin 300 mg and eicosapentaenoic acid (EPA) 2000 mg daily in individuals who had a screening colonoscopy in the English Bowel Cancer Screening Programme (BCSP). Aspirin treatment was associated with a 20% reduction in colorectal polyp number at BCSP surveillance colonoscopy 12 months later. It is unclear what happens to colorectal polyp risk after short-term aspirin use. AIM: To investigate colorectal polyp risk according to the original trial treatment allocation, up to 6 years after trial participation. METHODS: All seAFOod trial participants were scheduled for further BCSP surveillance and provided informed consent for the collection of colonoscopy outcomes. We linked BCSP colonoscopy data to trial outcomes data. RESULTS: In total, 507 individuals underwent one or more colonoscopies after trial participation. Individuals grouped by treatment allocation were well matched for clinical characteristics, follow-up duration and number of surveillance colonoscopies. The polyp detection rate (PDR; the number of individuals who had ≥1 colorectal polyp detected) after randomization to placebo aspirin was 71.1%. The PDR was 80.1% for individuals who had received aspirin (odds ratio [OR] 1.13 [95% confidence interval 1.02, 1.24]; p = 0.02). There was no difference in colorectal polyp outcomes between individuals who had been allocated to EPA compared with its placebo (OR for PDR 1.00 [0.91, 1.10]; p = 0.92). CONCLUSION: Individuals who received aspirin in the seAFOod trial demonstrated increased colorectal polyp risk during post-trial surveillance. Rebound elevated neoplastic risk after short-term aspirin use has important implications for aspirin cessation driven by age-related bleeding risk. ISRCTN05926847
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