Recovery of renal function after bilateral renal vein thrombo sis episode as complication of membranous glomerulopa thy: case report

<div><p>ABSTRACT Renal vein thrombosis (RVT) is a complication often associated with nephrotic syndrome. It occurs due to a state of hypercoagulability common in the diseases that attend to this syndromic diagnosis. It should be suspected whenever there is nephrotic syndrome associated with sudden flank pain, hematuria and worsening of proteinuria. Bilateral RVT also presents with frequently oliguric renal dysfunction. This case reports a 33-year-old patient hospitalized for a nephrotic syndrome, with etiologic investigation suggestive of primary membranous glomerulopathy, which evolved with bilateral RVT associated with deterioration of renal function and need for renal replacement therapy. He promptly performed angiography with thrombectomy and thrombolysis, evolving with recovery of renal function in two weeks.</p></div

Correlation between urinary MCP-1 and albuminuria in schistosomiasis patients.

<p>Correlation between urinary MCP-1 and albuminuria in schistosomiasis patients.</p

Demographic and clinical characteristics of the study population.

<p>Data are shown as mean ± SD or percentages. Significant P <0.05 <i>vs.</i> control by Student' <i>t</i> and Fisher's exact tests.</p><p>Demographic and clinical characteristics of the study population.</p

General laboratory parameters of hepatosplenic schistosomiasis patients and controls.

<p>Values are expressed as mean ± SD. Significant P<0.05 <i>vs</i> control by Student <i>t</i> test. P_Na+, plasma sodium; P_K+, plasma potassium; P_Ca2+, plasma calcium; P_P, plasma phosphorus; P_Cl-, plasma chloride; PMg2+, plasma magnesium AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma glutamyl transferase; INR, international normalized ratio.</p><p>General laboratory parameters of hepatosplenic schistosomiasis patients and controls.</p

Comparison of renal function in hepatosplenic schistosomiasis patients and controls.

<p>Values are expressed as mean ± SD. Significant P <0.05 <i>vs.</i> control by Student <i>t</i> test. P_Cr, plasma creatinine; P_Ur, plasma urea; GFR, glomerular filtration rate; MCP-1, Monocyte Chemotactic Protein-1 FE_Na+, fractional excretion of sodium; FE_Mg++, fractional excretion of magnesium; FE_K+, fractional excretion of potassium; TTKG, transtubular potassium transport; TcH2O, reabsorption of free water solute.</p><p>Comparison of renal function in hepatosplenic schistosomiasis patients and controls.</p

Acute kidney injury in critically ill obstetric patients: a cross-sectional study in an intensive care unit in Northeast Brazil

<div><p>Abstract Introduction: Acute kidney injury (AKI) is a complication still poorly studied in the setting of obstetric patients, which is associated with increased mortality. Objective: The aim of this study was to investigate the frequency and risk factors of AKI among critically ill obstetric patients. Methods: A cross-sectional study was conducted with all patients admitted to an intensive care unit (ICU) due to obstetric complications, in Fortaleza, Brazil, in the period between January 2012 and December 2014. AKI was defined according to AKIN criteria. Results: A total of 389 patients were included, aged between 13 and 45 years. The main causes of ICU admission were pregnancy-related hypertensive syndromes (54.5%), hemorrhage and hemorrhagic shock (12.3%), heart diseases (9.0%), respiratory insufficiency (8.2%) and sepsis (5.4%). AKI was found in 92 cases (24%), and this was the most frequent complication. General mortality was 7.5%, and mortality due to AKI was 21% (p = 0.0007). In the multivariate analysis, risk factors for AKI were cesarian delivery (95% CI = 0.23-0.85, p = 0.01) and thrombocythopenia (95% CI = 1.50-4.36, p = 0.001). AKI was an independent risk factor for death (OR = 6.64, 95% CI = 3.11-14.15, p < 0.001). Conclusion: AKI was the main complication among critically ill obstetric patients and it was associated with increased mortality. Most cases were associated with pregnancy-related hypertensive disorders, which are complications that can be easily identified and treated during prenatal care.</p></div