Noise Exposure in Workplace and Mtabolic Syndrome; Are They related?

Several studies confirmed the association of diabetes, hypertension, hyperlipidemia, obesity and high body mass index (BMI) on hearing loss among the general population. We think that same with the general population, we might have same association among workers that exposed with noise exposure in their workplaces. Therefore, this study aimed to examine the relationship between metabolic syndrome and noise-induced hearing loss among workers of the Iranian automobile industry. The present survey was performed on 606 workers of an Iranian automobile product factory. According to Noise exposure measurement, we divided workers into the noise-exposed (≥ 85 dB) and unexposed

Effect of Alcoholic Extract of Rosa canina on Hepatic Tissue and Hepatic Enzymes Activity in Diabetic Rats

Background & aim: Nowadays because of difficulty in the supply and injection of insulin and blood sugar reducing drugs and considering the side effects of chemical drugs, researcher’s attention is drawn to using herbal medicines. Liver is one of the organs affected by diabetes in different functional aspects. The purpose of this research was studying the effect of Rosa canina extract on reducing the adverse effects and improving diabetes symptoms related to histophysiology, amount of biochemical serum factors and liver enzymes in male rats. Methods: 32 male Wistar rats, weighed 200-220 gr, were divided into 4 groups. Diabetes was induced by intraperitoneal injection of STZ (60mg/kg). The period of experiments was 4 weeks. At the end of experiments, the rats were sacrificed and their serums were collected for measurement of liver enzymes. Also, histological sampling of liver was done. Statistical analysis was performed using analysis of variance (one-way ANOVA). Results: The results of this study showed that treatment with ethanol extract of Rosa canina led to significant reduction of liver enzymes in the Rosa extract-treated groups in comparison with the diabetic group, indicating the protective effect of alcoholic extract of Rosa canina on liver tissue against diabetes-induced damages. In liver histopathology, a distinct fat change in the lobular center areas was created in the diabetic group. Pathological changes were not significant in the liver of the Rosa extract-treated groups; liver in this group was relatively healthier than in diabetic group. Conclusions: Rosa extract improved this organ's function in STZ-induced diabetic rats by reducing serum biomarkers of liver pathology and reducing histological damages

Effect of ethanolic extract of Rosa canina on some serum biochemical parameters of diabetic male rats

The aim of the present study was to investigate the effect ethanolic extract of Rosa canina on some serum biochemical factors of diabetic male rats. Thirty two (32) male Wistar rats weighting 200 – 250 grams in 4 groups (control, diabetic control, diabetics + 250mg/kg/day extract, diabetics + 500 mg/kg/day extract) were used. Diabetes was induced by STZ (60mg/kg) intraperitoneal injection. The period of experiment was 4 weeks. At the end of experiments, the rats were sacrificed and their serums collected for glucose, creatinine, urea and albumin estimation. The results showed that glucose, creatinine and urea concentrations were significantly increased in the diabetic group (p<0.05), while the serum albumin concentrations was reduced. The levels of glucose, creatinine and urea in treated groups decreased significantly in comparison with the diabetic control group (p<0.05). But albumin concentrations showed no significant changes (p>0.05). The changes of glucose in treatment groups showed no significant differences (p>0.01).Keywords: Streptozotocin, Diabetic male rat, Rosa canina, Serum glucose, Creatinine, Albumin, Ure