8 research outputs found
The effect of Helicobacter pylori infection on gastric acid secretion in man
- Publication venue
- Publication date
- 01/01/1995
- Field of study
Helicobacter pylori (H pylori) infection is the commonest chronic bacterial infection world-wide. The work carried out in this thesis has sought to explore the effect of the infection on gastric secretory function in man. We developed a new test of gastric acid secretion using the substance gastrin releasing peptide (GRP) as the stimulus. Acid secretion measured in response to intravenous infusion of GRP reflects the combined functional response of the antrum and body of the stomach. It activates both stimulatory and inhibitory controls of acid secretion and in these respects it simulates the response to eating. The reproducibility of the GRP test was assessed and was found to be high for both gastrin and acid secretion. Using this new tool we studied acid secretion in a variety of subjects with and without H pylori infection. We have found that GRP stimulated acid secretion is increased six fold in DU patients with the infection compared to H pylori negative healthy volunteers (true normals). This exaggerated acid response is likely to represent a key pathophysiological defect which underlies DU disease. We have demonstrated for the first time that eradication of H pylori infection leads to normalisation of basal and GRP stimulated acid secretion in DU patients. These novel findings have shed considerable light on the understanding of the pathophysiology of DU disease and the role of H pylori infection in it. We have also shown for the first time that GRP stimulated acid secretion is increased two to three fold in H pylori positive healthy volunteers compared to true normals. This secretory abnormality also fully resolves following eradication of the infection. Since half the world's population is colonised with H pylori, it is essential that all future gastric secretory studies ensure that their control subjects are negative for the infection. The presence of the secretory abnormality in healthy volunteers may also be of relevance to other upper Gl diseases such as reflux disease. We proceeded to investigate the mechanism of the exaggerated acid response to GRP in DU patients and presented evidence compatible with this being due to impaired inhibitory control of acid secretion. We proceeded to examine the effect of the most commonly prescribed medication for dyspepsia, i.e. ranitidine, on acid secretion in healthy volunteers with and without H pylori infection. We showed that a two month course of ranitidine leads to a doubling of basal acid output and a 68% increase in GRP stimulated acid output two days after withdrawing treatment. This rebound acid hypersecretion is not associated with any significant change in gastrin concentrations and fully resolves within ten days of stopping ranitidine. These findings may offer an explanation for the common clinical problem of rapid resurgence of dyspeptic symptoms following discontinuation of acid suppressive therapy. Finally, we used the GRP test to study acid secretion in patients with non ulcer dyspepsia (NUD) and H pylori infection. We showed that a significant proportion of NUD patients had an exaggerated acid response to GRP similar to DU patients i.e. they displayed the DU diathesis. This raises the exciting possibility that this group of NUD patients may also be cured by eradication of their H pylori infection
Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey
- Author
- Abbas Ahmed Hosam Eldin Hasan
- Abbas Ghanem
- Abbas Hazem
- Abbatini Francesca
- Abdalbakheet Duaa
- Abdallah Emad
- Abdelazim Tarek
- Abdelaziz Nabil Yassin Tammam
- Abdelglil Momen
- Abdelhalim Ahmed
- Abdelhalim Mostafa Mohammed
- Abdelhamid Ahmed
- Abdelhamid Mohamed Sayed
- Abdelkhalik Morsi Mohamed Morsi
- Abdellatif Ahmed
- Abdelmageed Mohammed Elkassaby
- Abdelmaksoud Mohamed
- Abdelmohsen Ahmed
- Abdelmomen Ahmed Ezzat Elghrieb
- Abdelmoneim Ibrahim Tharwat Mohamed
- Abdelmonem Mohamed Ahmed
- Abdelmotaleb Hussien Ali
- Abdelrafee Ahmed
- Abdelrasheed Sayed
- Abdelsayed Emad Fahim
- Abdo Nael
- Abdulatef Shehab Ahmed Ali
- Abdullah Alqahtani Ali
- Abdulrahman Chadi
- Abdur-Rahman Lukman
- Abduraboh Abdullah Fayez
- Abed Ali Ibrahim Eldawy
- Abiodun Azeez Lateef
- Abiyere Henry
- Aboelmagid Hamdy Haggag Ebrahim
- Abolnasr Khaled Samir
- Abosi-Appeadu Kessewa
- Abouelnagah Galal
- Abozeid Ahmad Mahmoud
- Abozeid Mahmoud
- Abualkhair Wael
- Abualnaja Yousra
- Abualsel Abdulmenem
- Abuosba Abdelrahman
- Abusalem Osama
- Abusiam Wael
- Abutalib Raid Abdullah
- Abuzeid Mohamed Mostafa
- Addari Giulio
- Adebowale Yusuf
- Adejumo Adeyinka
- Adel Mohammed
- Adeoluwa Ojajuni
- Adeyeye Ademola
- Adly Ramy Magdy
- Adorisio Ottavio
- Agbonrofo Peter
- Agrawal Abhishek
- Ahmad Farooq
- Ahmad Misbahu Haruna
- Ahmad Mustafa
- Ahmad Sufian
- Ahmad Suhaib
- Ahmed Abeer Abdul Hameed
- Ahmed Arooj
- Ahmed Emad Ali
- Ahmed Hassan
- Ahmed Mohamed
- Ahmed Mostafa Mahmoud
- Aitali Abdelmounaim
- Akeel Nouf
- Akhtar Khalid
- Akin Furkan Atakan
- Akinmade Akinola
- Al Eisa Abdulmohsen
- Al Hassn Ibrahim
- Al Naeb Mohamed
- Al Turki Neamat Ahmed Ali
- Al-Bahrani Ahmed
- Al-Kubati Waheeb
- Al-Masari Hayder Makki
- Al-Sadery Humood
- Alaa Mohammed
- Alabbas Haytham
- Alafghani Haitham
- Alarabi Rayan
- Alawadhi Abdulbari Mohammed
- Alawady Mohammed
- Alawfi Homoud
- Alazzam Saleh
- Albadry Ali Almahdy Ali
- Albahooth Khalid
- Albalawi Ibrahim Altedlawi
- Albeshri Khalid A.
- Aleksandr Ogoreltsev
- Alfalah Haitham
- Algatanesh Nassib
- Alghamdi Faisal Saleh
- Alghamdi Saleh
- Alghuliga Abdullah
- Alhamdany Arkan Shubber
- Alharbi Abdulhamid
- Alhazmi Barrag
- Alhazmi Waleed
- Alhedaithy Alhanouf
- Alhendawey Moaaz
- Alhussaini Mohammed Khalid
- Alhussien Fade Ahmed
- Ali Ali Sayed
- Ali Bandar Idrees A.
- Ali Doaa
- Ali Mahmoud
- Ali Mohamed Anwar Abdel Razik
- Ali Muhammad Zulfiqar
- Ali Shabeer
- Ali Syed Muhammad
- Aliyu Yakubu
- Aljathlany Yousef
- Aljawhari Adel Ali
- Alkhalegy Ayman
- Alkhayat Ali
- Alkhayat Mohammed Amer
- Allaeys Mathias
- Almaghrabi Alhassan Hesham
- Almasri Mahmoud
- Almulhim Abdulrhman
- Alnabarawi Mahmoud
- Alnahas Yousef
- Alnashar Ahmed
- Alnoqaidan Emad
- Alomieri Adil
- Alotaibi Abdullah
- Alotaibi Abdulrahman
- Alotaibi Abdulrahman
- Alowairdhi Tumadher
- Alqarni Ahmed
- Alqasaby Abdallah
- Alqudaihi Heba
- Alrashidi Yousef
- Alsallum Ofays
- Alsawat Salem
- Alshabi Yaser Ahmad
- Alshehari Mohammed Mohammed Hasan
- Alshukr Sarah
- Alsuwaimel Munir A.
- Althobaiti Majid
- Althumali Abdullah
- Altomare Donato F.
- Alvarez Gallesio José Maria
- Alwan Ahmed
- Alwusaibie Ahmed
- Alyami Mohammad
- Alzahrani Khalid H.
- Alzahrani Saud
- Alzamanan Mahdi
- Alzamel Heythem
- Amal Benzakour
- Amary Mohamed Mokhtar
- Amen Mohamed Mohsen
- Amer Nasser Mohammed
- Amir Mohammed
- Amr Wesam
- Andrea Chierici
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- Andriola Valeria
- Angrisani Marco
- Angulo Victor Manuel Pinto
- Antonio D’Alessandro
- Anwer Mariyah
- Aoun Rany
- Arbutina Dragana
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- Aremu Isiaka
- Argenio Giulio
- Arnold Marion
- Arnouse Mohamed Mohamed Hamdy
- Asar Khalid Mohammad Ibrahim
- Ashimov Erkin
- Ashraf Tamer
- Asif Muhammad
- Aslam Mohammad
- Ateeb Mujammad
- Atef Gehad
- Atici Semra Demirli
- Attia Ahmed Mohamed
- Ayoub Larissa
- Azer Mina
- Aziz Mina
- Aziz Muhammad Akram Abdul
- Ba Mamadou
- Bacher Annica
- Bafaraj Ahmed
- Bagaglini Giulia
- Balla Andrea
- Barbary Hesham
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- Barbon Carlotta
- Basendowah Mohammed
- Bashah Moataz M.
- Bashir Umar
- Bashlachev Andrey
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- Bogdan Stoica
- Bonci Eduard-Alexandru
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- Brahmachari Swagata
- Bruzzaniti Placido
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- Campagnaro Tommaso
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- Dare Julius Kolajo
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- De Falco Nadia
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- Demeester Steve
- Depuydt Martijn
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- Doerner Johannes
- Dogjani Agron
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- Duran Erik Efrain Sosa
- Durayb Norah
- Dursun Ayberk
- Dziakova Jana
- Echevarria Miguel Jose Pinto
- Edassy Mohammed El
- Efetov Sergey
- Eke Grace
- El-Hussuna Alaa
- El-Wakeel Ayman
- Elalfy Khaled
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- Elbatal Amira Alsayed Abdelhai
- Eldeeb Ahmed
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- Eldesouki Mohammed Nabil
- Eldesouky Omnia
- Eleshra Ahmed
- Elfeki Hossam
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- Elhattab Ahmad
- Elhawary Ahmed Adel
- Elkafoury Ahmed
- Elkased Ahmed Farag
- Elkatt Mahmoud Mohamed
- Elkhouly Ahmed G.
- Elmesery Mohamed
- Elmetwally Ashraf S.
- Elmoghazy Mohamed Ibrahim
- Elnaghi Hisham
- Elnakash Ahmed Mostafa
- Elnemr Islam
- Elnour Ahmed Abd Elbaset Elsayed Abu
- Elrefai Mohamad
- Elsaied Adham
- Elsanhoury Kareem
- Elsanosi Abdelrhman Azhari Mohammed
- Elsayed Mohamed Abdelmoneim
- Elsayed Mohamed Ahmed Abdelhalim Ahmed
- Elseberbihy John Rezk Hanna
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- Elshazli Mostafa
- Elsheik Ahmed
- ElSheikh Ahmed M.
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- Elsorogy Mohamed
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- Elzayady Hany M.
- Elzayat Ibrahim
- Elzeftawy Shady Ahmed
- Emile Sameh Hany
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- Eral Burak
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- Fadel Bashir A.
- Fahiem Andrew
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- Fazli Mohammad Rafi
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- George Ihediwa
- Ghabisha Saif Ali
- Ghafoor Tariq
- Ghanem Ahmed
- Gharbia Mohamed
- Ghazala Mohamed Jomma
- Ghonim Mostafa
- Ghunaim Mohammed
- Giani Alessandro
- Giardino Alessandro
- Giarratano Gabriella
- Giuffrida Maria Carmela
- Giugliano Marco
- Golea Smain
- Gomez Caroina Gonzalez
- Gondal Zafar
- Gonzales Erick Ivan Huaman
- Gorin David
- Gots Alexander
- Grappelli Virgilio Michael Ambrosi
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- Hamed Hosam
- Hamed Mohamed Korayem Fattouh
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- Hamza Ahmed
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- Helmy Ahmed Hazem I.
- Hemidan Ahmed Gamal Abouelfetouh Ibrahim
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- Jasso Manuel Meza
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- Luc Jessica G. Y.
- Lule Herman
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- Mariateresa Grasso
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- Marra Angelo Alessandro
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- Martin-Perez Beatriz
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- Mazingi Dennis
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- Mirza Mohammad Amin
- Mitul Ashrarur Rahman
- Moeslein Gabriela
- Mohamed Mohamed Mohamed Adel
- Mohamed Anwar Yahya A.
- Mohamed Omnia Y.
- Mohammad Mohammad Aminu
- Mohammed Khalid Fathelrahman Bakier
- Mohammed Mahfoudh
- Mohammed Mahmoud M.
- Mohammed Mohammed Mustafa Hassan
- Mohammed Ouazni
- Mohmmed Mona Mhmoud
- Molena Daniela
- Montalbán Beatriz Cros
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- Mpaili Eustratia
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- Mudawi Ishag M.
- Muhammad Aneeqah Din
- Muresan Mihai-Stefan
- Mussa Haidar Aal
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- null null
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- Obure Ralph Ombati
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- Okunlola Abiodun Idowu
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- Oluyomi Ayodele Samuel
- Omar Mohamed I.
- Omar Tilioua
- Oosthuizen Pj
- Orecchia Luca
- Orlando Francesco
- Osman Khalid Abdalla Abdelgadir
- Osman Luqman
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- Paci Marco
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- Pakula Andrea M.
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- Salim Omer El Faroug H.
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- Shafique Muhammad Salman
- Shah Rahmat Ullah
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- Shaker George Samir Habib
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- Sharaf Hesham
- Sharafeldin Hatem Abdelrahman Ahmed
- Sharma Meenakshi
- Shawer Sami
- Shawer Sherif
- Shehata Mina
- Shemes Ayman
- Sherbiny Kareem El
- Sherif Ahmed Elshawadfy
- Shetiwy Mosab
- Shittu Asimiyu Adekunle
- Shomoye El-Zaki
- Sibiany Abdulrahman
- Siboe Mark M. W.
- Sidorova Lyudmila
- Sileri Pierpaolo
- Silva Jesús
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- Singh Baljit
- Siragusa Leandro
- Situ Oladele
- Skandalakis Georgios P.
- Slavchev Mihail
- Sleilati Fadi
- Sobh Mohamed Ramadan
- Sofan Mostafa
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- Soliman Ahmed
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- Stanislav Berelavichus
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- Styliani Vasileiadou
- Subramanian Sivaraman
- Suliman Omar AAbu
- Tabasi Hani
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- Tairab Elsanousi Ibrahim Sabir
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- Van Praet Charles
- Van Ramshor Gabrielle H.
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- Vikrantmr Sharma
- Villwock Jennifer
- Visconti Diego
- Vishwakarma Kushagra
- Vosloo Susan
- W Njoroge P.
- Waleed Aasma
- Wali Zubair
- Waqar Shahzad Hussain
- Warusavitarne Janindra
- Waseem Talat
- Wexner Steven
- Wuraola Funmilola Olanike
- Yacir El Alami
- Yakar Fatih
- Yanaga Katsuhiko
- Yassin Nouf
- Yassine Wassim Abou
- Yeşilyurt Değercan
- Yildiz Alp
- Yousef Yousef Mohamed
- Youssef Mohamed
- Youssef Youssef Abdel Aziz
- Yves Van Nieuwenhove
- Zafar Noman
- Zahra Tarek
- Zaidi Mariam
- Zaieem Mohammad
- Zakaria Hazem M.
- Zakharenko Alexander
- Zancana Giuseppa
- Zentar Aziz
- Zese Monica
- Zewar Karem Shahin Mohamed
- Zidan Ahmed Azmy
- Zigiotto Daniele
- Zubayraeva Albina
- Zuhdy Mohammad
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. Methods: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through an online platform from June 14th to July 15th, 2020. The primary outcome was the burden of burnout during the pandemic indicated by the validated Shirom-Melamed Burnout Measure. Results: Nine hundred fifty-four surgeons completed the survey. The median length of practice was 10 years; 78.2% included were male with a median age of 37 years old, 39.5% were consultants, 68.9% were general surgeons, and 55.7% were affiliated with an academic institution. Overall, there was a significant increase in the mean burnout score during the pandemic; longer years of practice and older age were significantly associated with less burnout. There were significant reductions in the median number of outpatient visits, operated cases, on-call hours, emergency visits, and research work, so, 48.2% of respondents felt that the training resources were insufficient. The majority (81.3%) of respondents reported that their hospitals were included in the management of COVID-19, 66.5% felt their roles had been minimized; 41% were asked to assist in non-surgical medical practices, and 37.6% of respondents were included in COVID-19 management. Conclusions: There was a significant burnout among trainees. Almost all aspects of clinical and research activities were affected with a significant reduction in the volume of research, outpatient clinic visits, surgical procedures, on-call hours, and emergency cases hindering the training. Trial registration: The study was registered on clicaltrials.gov "NCT04433286" on 16/06/2020
Expression of cyclooxygenase-2 in human sporadic colorectal adenomas
- Publication venue
- Publication date
- 01/04/2006
- Field of study
Assessment of inflammatory cell phenotype in sporadic hyperplastic polyps
- Publication venue
- Publication date
- 01/04/2007
- Field of study
COX-2 gene polymorphisms and association with premalignant changes in the stomach
- Author
- Publication venue
- Publication date
- 01/04/2005
- Field of study
Inflammatory bowel disease
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
- Author
- Aamir Junaid
- Abaalkhail Muath
- Ababneh Adnan
- Ababneh Hazim
- Ababneh Laila
- Ababneh Roba
- Abad-Motos Ane
- Abaker Mussab
- Abary Ryan
- Abass Adam
- Abate Emmanuele
- Abayomi Olukayode
- Abazeed Alaa
- Abbad Bader
- Abbadessa Francesco
- Abbadi Osaid
- Abbakar Malaz
- Abbas Ahmed
- Abbas Alzhraa
- Abbas Asad
- Abbas Aya
- Abbas Jihad
- Abbas Manzar
- Abbas Mohammad
- Abbas Omer
- Abbasov Aykhan
- Abbo Olivier
- Abbott Daniel
- Abbott Tom
- Abboud Omar
- Abd Waleed
- Abd-Elkariem Ahmed
- Abd-Elsalam Sherief
- Abdalah Ahmad
- Abdalhadi Alya
- Abdalla Ahmed
- Abdalla Eman
- Abdalla Samir
- Abdalla Shimaa
- Abdalla Siddig
- Abdallah Emne
- Abdallah Ghaida
- Abdallah Lubna
- Abdallah Munir
- Abdallah Murad Al
- Abdallah Rasha
- Abdalnour Hani
- Abdeen Bashar
- Abdeewi Saedah
- Abdeh Louai
- Abdel-Aleem Mahmoud
- Abdel-Elsalam Wafaa
- Abdel-Fattah Areej
- Abdel-Fattah Nour
- Abdel-Hafez Ibrahim
- Abdelaal Abdelrahman
- Abdelaty Ahmed Adel
- Abdelazeem Khaled
- Abdelaziz Areej
- Abdelaziz Mohammed
- Abdelbagi Mohamad
- Abdelbaset Abouelnour
- Abdeldayem Hesham
- Abdelfattah Mahmoud
- Abdelgadir Alwaleed
- Abdelgalel Khaled
- Abdelghafar Moslem
- Abdelhafez Mohammed
- Abdeljalil Abdelkarim
- Abdelkabir Mohammed
- Abdelkareem Mohamed
- Abdelkarem Mohamed
- Abdelkarim Mostafa
- Abdelkhalek Mohamed
- Abdellah Fatima
- Abdelmajeed Ahmed
- Abdelmalik Abubaker
- Abdelmawla Ahmed
- Abdelrahman Abdelrahman
- Abdelrahman Haneen
- Abdelraouf Ali
- Abdelsamed Ahmed
- Abdelwahab Omar
- Abderrazaq Hafni
- Abdissa Desalegn
- Abdo Adnan Sayid
- Abdou Hossam
- Abdou Mostafa
- Abdoun Meriem
- Abdow Mohammad
- Abdrabou Ahmed
- Abdualqader Mahmmoud
- Abdul-Jabar Hani
- Abdul-Mumin Alhassan
- Abdulaal Safaa
- Abdulateef Omar
- Abdulfattah Ammar Yasser
- Abdulkareem Amal
- Abdull Mohammed
- Abdullaev Abakar
- Abdullah Abdullah
- Abdullah Bahiyah
- Abdullah Duha Milad
- Abdullah Muhammad Tariq
- Abdullah Nabila
- Abdullah Saleha
- Abdullah Shahbaz
- Abdullaha Lamess
- Abdullahi Alhassan
- Abdullahi Habiba
- Abdullahi Lawal
- Abdullahi Mohammed Kabir
- Abdullahi Sani
- Abdullahi Yasir Younis
- Abdulmalek Abdulmalek
- Abdulmalik Abdulmuez
- Abdulmohsen Ahmed
- Abdulqawi Nabil
- Abdulrahem Abdullah
- Abdulrahman Mamuda
- Abdulrahman Mohamed
- Abdulrahman Taha
- Abdulsalam Albaraa
- Abdulsalam Fareed
- Abdulsalam Khalifa
- Abdulsalam Moruf
- Abdulwahab Taiceer
- Abdulwahed Eman
- Abdunabi Murad
- Abdur-Rahman Lukman
- Abdurab Ebrahim
- Abdurehman Oumer
- Abdurrazzaaq Abdussemee
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abe Anthonia
- Abe Nobutsugu
- Abe Tatsuro
- Abebe Engida
- Abebe Kirubel
- Abebe Metasebia
- Abebe Nebyou
- Abebrese John Tabiri
- Abed Arsan Abu
- Abed Francisco
- Abed Haneen
- Abed Laith Abu
- Abedalqader Lina
- Abedin Yasmin
- Abel Joel Reuben
- Abel Livingston
- Abel Mary Kathryn
- Abelevich Alexander
- Abella Andrei Cesar
- Abichou Wijden
- Abid Rubaba
- Abiodun Adekunle
- Abiola Olajide
- Abiola Paul
- Abiyere Henry
- Aboalsamh Ghaleb
- Aboazamazem Hajir
- Abodeeb Aya
- Aboelkhel Roger
- Abojeila Farah
- Abosamak Nour Eldin
- Abosnaina Yahya
- Abostate Ahmed
- Abou-Abbass Hussein
- Abou-Khalil Jad
- Abouassi Layth
- Abouassi Majd
- Aboubakr Samar
- Aboubeirah Mohammed
- Abouelazayem Mohamed
- Abouelnagah Galal
- Abouelnagah Yossof
- Aboutaleb Shereen
- Aboutrab Ayham
- Abouzid Amr
- Abozied Hesham
- Abraham Bejoy
- Abrahams Jenevive
- Abramowicz Shelly
- Abrate Alberto
- Abreha Tassew
- Abrha Teklebirhan
- Abu-Arish Hamdoon
- Abu-Eisheh Basil
- Abu-Ishkerih Nizar
- Abu-Ismail Luai
- Abu-Libdeh Tareq
- Abu-Mehsen Marah
- Abu-Zaid Ahmed
- Abualteen Faisal
- Abuawad Carla
- Abubakar Abdullah
- Abubakar Ahmed
- Abubakar Mohammed Kabir
- Abubakr Abubakr
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- Abubeih Hossam
- Abud Burçin
- Abudari Hadeel
- Abudher Abdulhafid
- Abuhamour Ehab
- Abuissa Khatab
- Abukhadra Mahmoud
- Abukhalaf Sadi A
- Abukhater Muhammad
- Abulafia Daniel
- Abuleil Amro
- Abulshuwashi Nayrouz Abdullah
- Abumahara Saleh
- Abunawas Huthifa
- Aburahmah Mohammad
- Aburayyan Fatima
- Aburima Sarah
- Abusabeib Abdelrahman
- Abusadah Samer
- Abusalem Marwa
- Abusannoga Malek
- Abushahma Ahmed Omar
- Abutaka Ahmad
- Abutaleb Malak
- Abuzaina Khalil
- Acatrinei Eduard
- Accarino Giulio
- Accorsi Guilherme
- Acharya Hriday
- Acharya Metesh
- Acharya Shivanie
- Achimas-Cadariu Patriciu
- Ackermann Travis
- Acosta Jesus
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- Acosta Yancy
- Acosta Úrsula
- Acquaye Jane
- Acra-Tolari Ricardo
- Acuña Gastón
- Adam John
- Adamala Soujanya
- Adamina Michel
- Adamoli Laura
- Adams Katie
- Adapa Akshath
- Addas Bassam
- Adebajo Emmanuel
- Adebanjo Ademola
- Adebara Idowu
- Adebayo Olaolu
- Adebayo Sikiru A
- Adeboyejo Oluwaseun
- Adegbola Samuel
- Adel Dina
- Adelaja Aderinsola
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- Ademuyiwa Adesoji
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- Adikaibe Valentine
- Adil Md Tanveer
- Adisa Adewale
- Aditianingsih Dita
- Adjeso Theophilus
- Adlan Alsafe
- Adler Tina
- Admasu Azarias
- Adofo-Asamoah Yvonne
- Adrees Mohammed
- Adrianzén Marcos
- Adu-Aryee Nii Armah
- Aduse-Poku Maame
- Advani Rajeev
- Adze Joel
- Aeed Majed
- Afaque Syed Nayyar
- Afifi Amgad
- Afifi Eman
- Afifi Nermeen
- Afify Abdelrahman
- Afolabi Abdulrahman O
- Afolabi Akinwale
- Afolabi Bosede
- Afshar Salim
- Aftab Raiyyan
- Afuwape Oludolapo
- Afzal Ameer
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- Afzal Mohamed
- Afzal Muhammad Farooq
- Afzal Sadia
- Agalianos Christos
- Agapov Mikhail
- Agarwal Anjoo
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- Agbadebo Mouhamed
- Agbaje Ademola
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- Agboadoh Nelson
- Agbonrofo Peter
- Ageeli Mohammed
- Aggarwal Gaurav
- Aggarwal Manisha
- Aggarwal Sonali
- Aghababyan Kristina
- Aghadi Ifeanyi
- Aghalarov Ilgar
- Aghamaliyev Ughur
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- Agida Eyaofun
- Agnes Annamaria
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- Agoncillo Anika Johanna
- Agossou Hermann
- Agrawal Amit
- Agrawal Mansi
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- Agrawal Sanjit Kumar
- Agrawal Tulika
- Agro Felice Eugenio
- Aguado Héctor J
- Aguayo Omar
- Aguilar Ana
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- Aguilera-Arevalo Maria-Lorena
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- Agyapong Meshach Manu
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- Ahamed Waseem
- Ahangari Roghayyeh
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- Ahlaou Hamza
- Ahluwalia Saravpreet
- Ahmad Afaf
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- Ahmad Maleeha
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- Ahmad Niarah
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- Ahmadi Navid
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- Ahmed Abdelkareem
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- Ahmed Abedelrahman
- Ahmed Ahme
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- Ahmed Islam
- Ahmed Jawad
- Ahmed Kaleem
- Ahmed Khalid
- Ahmed Maira
- Ahmed Malik Shakeel
- Ahmed Manhal
- Ahmed Mariam
- Ahmed Moaiad Eldin
- Ahmed Mohamme
- Ahmed Muhammed
- Ahmed Nasir
- Ahmed Nauman
- Ahmed Omar
- Ahmed Safia
- Ahmed Sara
- Ahmed Shahnoor
- Ahmed Shakil
- Ahmed Sheraz
- Ahmed Waheed-Ul-Rahman
- Ahmed Waqas
- Ahmed Zubair
- Ahmedin Mahlet
- Ahsan Kunwar Armash
- Ahseen Naeimah
- Ahtash Abdurahman
- Aidarov Askar
- Aigner Felix
- Aiken Taylor
- Ailabouni Ramez
- Aimé Adeline
- Aiolfi Alberto
- Airoldi Angelo
- Aisuodionoe-Shadrach Oseremen
- Aitken Jake
- Aizza Giada
- Ajab Shereen
- Ajagha Okeoghene
- Ajai Olalekan
- Ajaj Hatem
- Ajami Dany
- Ajao Akinlabi
- Ajayi Adekunle
- Ajayi Peter
- Ajcip Gaby
- Ajekwu Samuel
- Ajekwu Temitope
- Aji Narjiss
- Aji Sani Ali
- Ajibola Hafees
- Ajiboye Olalekan
- Ajlan Abdulrazag
- Ajmi Ghadeer Al
- Ajmi Khalil Al
- Ajomah Nadia
- Akaba Godwin
- Akadh Ali
- Akalin Murat
- Akani Chris
- Akanni Bolaji
- Akbar Ali
- Akbar Bilal
- Akbar Hazrat Akbar
- Akbari Amir Ali
- Akbas Ahmet
- Akdeniz Yesim
- Akeel Nouf
- Akgor Utku
- Akhavizadegan Hamed
- Akhbari Melika
- Akhtar Amina
- Akhtar Fahad
- Akhtar Muhammad Adeel
- Akhtar Muhammad Shaheer
- Akhtar Munazza
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- Akhtar Tasleem
- Akhund Ramsha
- Akiely Jehad
- Akililu Yemisirach Bizuneh
- Akin Emrah
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- Akindoyin Success
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- Aklilu Abenezer Tirsit
- Akmercan Ahmet
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- Akram Shahzad
- Aktaa Nazeeh Al
- Akthar Farah
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- Akulaev Anton
- Akyol Cihangir
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- Al-Masri Mahmoud
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- Al-Mohammad Abdulrahman
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- Al-Qannass Ali
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- Al-Shaye Ahmad
- Al-Shazly Mohammed Hamdy
- Al-Shehari Mohammed
- Al-Shibi Abdallah
- Al-Shudifat Abdel-Ellah
- Al-Sihan Mutlaq
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- Al-Sukaini Ahmad
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- Al-Terki Abdullatif
- Al-Thaher Mohammad
- Al-Urfan Mohammed
- Al-Uzri Muntadhir
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- Al-Yahri Omer
- Al-Yaseen Mustafa
- Al-Zaazaai Zakarya Abdullah
- Al-Zazay Karim
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- Alaa Sherif
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- Alabdulkarim Yousof
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- Aladaileh Ammar
- Aladawi Omar
- Alade Samuel
- Aladelusi Timothy
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- Alahaidib Adel
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- Alahmadi Ibrahim
- Alahmari Ahmed
- Alahmed Salman
- Alajaji Nouf
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- Alakaloko Felix
- Alakeel Deem
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- Alayed Ahmad
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- Alazabi Basma
- Alazzeh Ghaleb
- Alba J Jr
- Albaba Basil
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- Albader Ibtisam
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- Albanese Erminia
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- Albarrak Abdullah
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- Albasheer Mohammad
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- Albawardy Nof
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- Albishty Nouran
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- Aldakhil Ahmad
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- Aldana Joel
- Aldebeyan Wassim
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- Aleksandrova Evgeniya
- Aleksić Lidija
- Alelwany Aisha
- Alemanno Giovanni
- Alemu Berhanu
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- Alemán María
- Alesmail Abdulkarim
- Alexakis Nicholas
- Alexander Dinesh
- Alexander Golomidov
- Alexander Philip
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- Alexandrou Andreas
- Alexe Vlad
- Alfarah Mohammad
- Alfaro Hilda
- Alfaro Valeria Cormane
- Alfaro-Goldaracena Alejandro
- Alfarra Dina
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- Alfeqeeh Ahmed
- Alferdaus Abdallah
- Alfieri Alex
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- Alghamdi Abdulaziz
- Alghamdi Abdullah A
- Alghamdi Ahmad
- Alghamdi Ibtihal
- Alghamdi Rami
- Alghamdi Susan
- Alghazal Thabet
- Alghazo Abdallah
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- Alhadi Abdulmueti
- Alhag Albrra
- Alhaidari Ammar
- Alhaje Awatif
- Alhajji Zahrah
- Alhakami Nuraddin
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- Alhami Haneen Ahmad
- Alhamid Ahmad
- Alhamid Aos
- Alhamid Mohammad
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- Alhammali Tariq
- Alharthi Bandar
- Alharthi Mohammed
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- Alharthi Sultan
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- Alhindi Rahaf
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- Alhouri Ahmad
- Alhunaidi Omar
- Alhussaini Ali
- Alhussein Ahmad
- Alhuthayl Meshari
- Ali Abdifatah Dahir
- Ali Abrar Ashraf
- Ali Ahmed
- Ali Ahsan
- Ali Aisha Mansoor
- Ali Almigdad
- Ali Ammar
- Ali Amna
- Ali Aneeqa
- Ali Aoun
- Ali Danish
- Ali Douaa
- Ali Faizah
- Ali Ghazanfar
- Ali Ibrahim
- Ali Imran
- Ali Imran Ali
- Ali Irfan
- Ali Marah
- Ali Maria
- Ali Mehboob
- Ali Mohamed
- Ali Mostafa
- Ali Muhammad
- Ali Muhammad Usman
- Ali Noman
- Ali Roshneen
- Ali Sadaf
- Ali Salem
- Ali Samar
- Ali Sana
- Ali Wagdi
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- Ali Zaid Al-Sheikh
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- Alias Alfonso
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- Aliwa Mohamed
- Aliwy Marwan Al
- Aliyeva Gunay
- Aliyeva Zumrud
- Aliyu Mohammed Salele
- Alizadeh Narges
- Aljabali Alaa
- Aljabri Maniee
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- Moawad Karim Abdelraouf
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- Otaibi Faisal Al
- Picciochi Maria
- Pinto João Almeida
- Polo Miriam Abdulkarim
- Qadhi Hani Al
- Qudhaya Rashed Al
- Qureshi Talha Ahmed
- Rahim Norazila
- Rahman Noorneza Abdul
- Rahman Norhafiza
- Raisi Amani Al
- Rashed Asmaa Al
- Rego Juliana Almeida
- Riaz Shujat Ahmed
- Riobello Eva Andreu
- Riyami Nihal Al
- Riyami Salim Al
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- Salam Omar Abdul
- Salama Ibrahim Abdelkader
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- Sebastian Isabel Alonso
- Shaalah Ahmed Abdullah
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- Shaikh Shafqat Ali
- Shanab Ahmed Abo
- Sharie Ahmed Al
- Shukri Asmaa Al
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- Smadi Omar Al
- Soares Rui Costa
- Soucheiron Maria Coronas
- Subaie Saud Al
- Suyyagh Kais Al
- Tarieh Ammar Abu
- Torres Eva Alvarez
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- Villamayor Verónica Alen
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- Virgilio Edoardo
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- Vishnoi Jeewan Ram
- Vishwakarma Sunil Kumar
- Vishwani Vartika
- Vissapragada Ravi
- Viste Claire
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- Viveros-Carreño David
- Vives Inmaculada
- Vives-Barquiel Marian
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- Vix Michel
- Vlad Ioan Catalin
- Vlad Schitcu
- Vladimir Novgorodskii
- Vleminckx Nils
- Vo Uyen Giao
- Vogel Jon
- Vogel Keianna
- Vogel Rachel
- Vogelsang Holger
- Vogler Thomas
- Vogt Kelly
- Vohra Ravinder
- Vokshi Ismail
- Volkova Olga
- Volpe Gustavo Jardim
- Volpin Enrico
- Volpin Francesco
- von Ehrlich-Treuenstätt Viktor H
- von Renesse Janusz
- von Rundstedt Friedrich-Carl
- Voonna Murali Krishna
- Voppuru Saiesh Reddy
- Vora Sameer
- Voros Peter
- Vosoughi Fardis
- Vossler Kristen
- Vounckx Manon
- Vourganti Srinivas
- Vovola Fernanda
- Vozian Marin
- Vrakopoulou Gavriella Zoi
- Vömel Jacob
- Wadei Hajr Al
- Yahya Zakaria Al
- Zahran Mohammed
- Zahrani Attiya Al
- Zahrani Turki Ai
- Zaid Muna
- Zein Zeina Al
- Álvarez Sofia
- Älgå Andreas
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2021
- Field of study
Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.
Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty.
Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year.
Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population
Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms
- Author
- Abbas Syed Ali
- Abdalasalam Sabriya
- Abdalhadi Alaa Abdalfattah
- Abdalla Fadlalla Asgad Osman
- Abdalla Naana Reyam
- Abdalla Walaa
- Abdalrheem Almthani Hamza
- Abdalsalam Ashraf
- Abdeewi Saedah
- Abdelgaum Esraa Hassan
- Abdelghafar Yomna Ali
- Abdelhalim Mohamed
- Abdelkabir Mohammed
- Abdelrahman Mohammedahmed Manahil Omer
- Abdelrahman Israa
- Abdelrhman Abdallahrs Asia Atif
- Abdukahil Sheryl Ann
- Abdulbaqi Lamees Adil
- Abdulhamid Salaheddin
- Abdulhamid Widyan
- Abdulkadir Nurul Najmee
- Abdullah Duha Milad
- Abdulwahed Eman
- Abdunabi Rawad
- Abe Ryuzo
- Abebrese Franklina Korkor
- Abel Laurent
- Abodina Ahmed Mohammed
- Abrous Amal
- Absil Lara
- Abu Salem Talat Ahmed
- Abusalama Abdurraouf
- Abuzaid Tareg Abdallah
- Acharya Subhash
- Acker Andrew
- Adam Elisabeth
- Adem Safia
- Ademnou Manuella
- Adewhajah Francisca
- Adrião Diana
- Ads Alaa Mohamed
- Adusei Amos Amoako
- Afum-Adjei Awuah Anthony
- Agbogbatey Melvin
- Ahmed Khalil Reham Abdelhamid
- Ahmed Mohamed Abdelaziz Ali Mostafa
- Ahmed Aya Mustafa
- Ahmed Musaab Mohammed
- Ahmed Shakeel
- Ainscough Kate
- Airlangga Eka
- Aisa Tharwat
- Aisha Ali
- Aisha Bugila
- Akimoto Takako
- Akmal Ernita
- Akwani Chika
- Al Ageel Saleh
- Al Qasim Eman
- Al-Aquily Mohammed
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Al-Saba'a Yousef
- Alajeeli Ahmed
- Alali Ahmed
- Alalqam Razi
- Alameen Aliya Mohammed
- Alaraji Zainab Ahmed
- Alaraji Zinah A.
- Albakry Khalid
- Albatni Safa
- Alberti Angela
- Aldabbourosama Osama
- Aldhalia Amer
- Aldoukali Abdulkarim
- Alegesan Senthilkumar
- Alessi Marta
- Alex Beatrice
- Alexandre Kévin
- Alflite Asil
- Alfoudri Huda
- Alhadad Qamrah
- Alhaddad Hoda Salem
- Alhouri Ahmad Nabil
- Alhouri Hasan
- Ali Mohammed Abdelmalek Awad
- Ali Adam
- Ali Imran
- Ali Syed Muneeb
- Alidjnou Kazali Enagnon
- Aljadi Mahmoud
- Aljamal Sarah
- Alkahlout Mohammed
- Alkaseek Akram
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Almasri Lana
- Almjersah Abdulrahman
- Alqandouz Raja Ahmed
- Alrfaea Walaa
- Alrifaee Moayad
- Alsaadi Rawan
- Alshareea Entisar
- Alshenawy Eslam
- Altaf Aneela
- Alves João
- Alves João Melo
- Alves Rita
- Alyasiri Mohammed Saleh
- Amaral Maria
- Amer Amro Essam
- Amira Nur
- Amuasi John
- Andini Roberto
- Andrejak Claire
- Angheben Andrea
- Angoulvant François
- Ankrah Sophia
- Ansari Muhammad Imran
- Ansart Séverine
- Anthonidass Sivanesen
- Antonelli Massimo
- Antunes de Brito Carlos Alexandre
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Arancibia Francisco
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Argin G.
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Ascofare Oumou Maiga
- Asensio Angel
- Ashley Elizabeth A.
- Ashraf Muhammad
- Ashraf Muhammad Sheharyar
- Asiedu-Bekoe Franklin
- Asif Namra
- Asim Mohammad
- Assi Grace
- Assie Jean Baptiste
- Asyraf Amirul
- Atangana Fouda
- Atia Ahmed
- Atif Minahel
- Atikah Ahmad Ridzuan Siti Nurul
- Atique Anika
- Atlowly Moad
- Attanyake AM Udara Lakshan
- Auchabie Johann
- Aumaitre Hugues
- Auvet Adrien
- Axelsen Eyvind W.
- Ayad Ared
- Ayadi Kamaluddin Muhammad Aisar
- Azemar Laurène
- Azizeldin Mohammed
- Azoulay Cecile
- Babatunde Hakeem
- Bach Benjamin
- Bachelet Delphine
- Badr Claudine
- Baig Nadia
- Baillie John Kenneth
- Baird J Kevin
- Bak Erica
- Bakakos Agamemnon
- Bakar Nazreen Abu
- Bakeer Hibah Bileid
- Bakri Ashraf
- Bal Andriy
- Balakrishnan Mohanaprasanth
- Bandoh Irene
- Banheiro Bruno Sarmento
- Bani-Sadr Firouzé
- Barbalho Renata
- Barbosa Nicholas Yuri
- Barclay Wendy S.
- Barnett Saef Umar
- Barnikel Michaela
- Barrasa Helena
- Barrigoto Cleide
- Bartoli Marie
- Baruch Joaquin
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- de Loughry Gillian
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- Doherty Helen
- Dominguez Carmen Infante
- Dondorp Arjen M.
- Donnelly Christl A.
- Donohue Sean
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- Fowler Robert A.
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- Franch-Llasat Diego
- França Rafael Freitas de Oliveira
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- Freire Marcela Vieira
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- Greene Courtney
- Greenhalf William
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- Groenendijk Albert
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- Hamer Ansley
- Hamers Raph L.
- Hamidfar Rebecca
- Hammarström Bato
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- Houltham Stuart
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- Kartsonaki Christiana
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- Kho Michelle E.
- Khoo Denisa
- Khoo Ryan
- Khoo Saye
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- Kim Jae Burm
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- Kindgen-Milles Detlef
- Kitamura Nobuya
- Kjetland Kjetland Eyrun Floerecke
- Klenerman Paul
- Klont Rob
- Knight Stephen R.
- Kobbe Robin
- Kodippily Chamira
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- Laffey John G.
- Lafhej Nadhem
- Lagrange Marie
- Laine Fabrice
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- Lolong Navy
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- Lopes Diogo
- Lopez-Colon Dalia
- Loschner Anthony L.
- Loubet Paul
- Loufti Bouchra
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- Lungu Olguta
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- Mahmoud Abdelaal Abdelrahman Yehia
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- Maia Ana Raquel
- Maier Lars S.
- Maillet Mylène
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- Majeed Nimisha Abdul
- Malfertheiner Maximilian
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- Martinot Martin
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- Maslove David
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- May Juergen
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- Mazzoni Thierry
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- McDermott Sherry
- McDonald Sarah E.
- McElroy Aine
- McElwee Samuel
- McEvoy Natalie
- McGeer Allison
- McLean Kenneth A.
- McNally Paul
- McNicholas Bairbre
- Meaney Edel
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- Mentzer Alexander J.
- Mercier Emmanuelle
- Mercier Noémie
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- Merson Laura
- Merson Laura
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- Meyer Dan
- Meynert Alison M.
- Meysonnier Vanina
- Mezidi Mehdi
- Michelanglei Céline
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- Miranda-Maldonado Hugo
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- Mohamed Elsayed Abdelhalim Ahmed Reda
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- Mohammed Libya
- Mohammed Nassima Si
- Mohammedelhassan Omer Abdullah
- Mohan Shetty Dr. Rajesh
- Moharam S. A.
- Mohd Noordin Nurul Amani
- Mohd Thabit Alif Adlan
- Mohd-Hanafiah Farah Nadia
- Moin Asma
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- Vidal José Ernesto
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- Villoldo Andrea
- Vishwanathan Gayatri
- Visseaux Benoit
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- Vongsouvath Manivanh
- Vonkeman Harald
- Vuotto Fanny
- Wahab Noor Hidayu
- Wahab Suhaila Abdul
- Wahid Nadirah Abdul
- Wainstein Marina
- Walsh Laura
- Wang Chih-Hsien
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- Wei Jia
- Wei Jia
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- Wen Tan Pei
- Wesam Hassi
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- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Sue
- Williams Bailey
- Williams Patricia J.
- Williams Virginie
- Wils Evert-Jan
- Wils Evert-Jan
- Wittman Jessica
- Wong Calvin
- Wong Teck Fung
- Wong Xin Ci
- Wong Yew Sing
- Wright Natalie
- Xian Lim Saio
- Xynogalas Ioannis
- Yamazaki Masaki
- Yang Toh Jordan Zhien
- Yarad Elizabeth
- Yazdanpanah Yazdan
- Yelnik Cécile
- Yeoh Chian Hui
- Yerkovich Stephanie
- Yiaye Touxiong
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Yuliarto Saptadi
- Zaaqoq Akram
- Zabbe Marion
- Zabert Gustavo E.
- Zacharowski Kai
- Zahid Masliza
- Zahran Maram
- Zambon Maria
- Zambrano Miguel
- Zanella Alberto
- Zaynah Nurul
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- Publication date
- 30/05/2024
- Field of study
Background: COVID-19 is primarily known as a respiratory illness; however, many patients present to hospital without respiratory symptoms. The association between non-respiratory presentations of COVID-19 and outcomes remains unclear. We investigated risk factors and clinical outcomes in patients with no respiratory symptoms (NRS) and respiratory symptoms (RS) at hospital admission. Methods: This study describes clinical features, physiological parameters, and outcomes of hospitalised COVID-19 patients, stratified by the presence or absence of respiratory symptoms at hospital admission. RS patients had one or more of: cough, shortness of breath, sore throat, runny nose or wheezing; while NRS patients did not. Results: Of 178,640 patients in the study, 86.4 % presented with RS, while 13.6 % had NRS. NRS patients were older (median age: NRS: 74 vs RS: 65) and less likely to be admitted to the ICU (NRS: 36.7 % vs RS: 37.5 %). NRS patients had a higher crude in-hospital case-fatality ratio (NRS 41.1 % vs. RS 32.0 %), but a lower risk of death after adjusting for confounders (HR 0.88 [0.83-0.93]). Conclusion: Approximately one in seven COVID-19 patients presented at hospital admission without respiratory symptoms. These patients were older, had lower ICU admission rates, and had a lower risk of in-hospital mortality after adjusting for confounders