2 research outputs found
Additional file 2: Figure S1. of Circulating mutational portrait of cancer: manifestation of aggressive clonal events in both early and late stages
ctDNA mutational landscape for major cancer groups for the top 30 genes in total cohort. Figure S2. ctDNA mutational landscape of patients’ stage known for the top 30 genes in lung cancer cohort. Figure S3. Higher mutation numbers in the ctDNA are associated with decreased survival in lung cancers. Higher mutation numbers in ctDNA are associated with poor survival. “n” defines the number of mutations and survival plots are separated by mutation numbers: n = 1, 2, 3, 4, 5, and 6 mutations. Blue lines indicate more than “n” mutations and the pink lines indicate equal to or less than “n” mutations. P-values were derived using the log-rank test. Figure S4. The concordance of top mutated genes in the ctDNA and tDNA of 37 lung cancer patients. (DOC 1098 kb
Additional file 1: Table S1. of Circulating mutational portrait of cancer: manifestation of aggressive clonal events in both early and late stages
Clinical and treatment characteristics of the 18 cases with no ctDNA alterations detected. Table S2. Description of mutation load in total cohort (n = 177). Table S3. All mutations detected in patient ctDNA compared with other studies. (DOC 625 kb