Comparative genomic assessment of Multi-Locus Sequence Typing: rapid accumulation of genomic heterogeneity among clonal isolates of -1

Io data has been colour-coded according to data interpretation thresholds described in Taboada . []. Strains showing discordant clustering results are boxed in green.<p><b>Copyright information:</b></p><p>Taken from "Comparative genomic assessment of Multi-Locus Sequence Typing: rapid accumulation of genomic heterogeneity among clonal isolates of "</p><p>http://www.biomedcentral.com/1471-2148/8/229</p><p>BMC Evolutionary Biology 2008;8():229-229.</p><p>Published online 8 Aug 2008</p><p>PMCID:PMC2527321.</p><p></p

Comparative genomic assessment of Multi-Locus Sequence Typing: rapid accumulation of genomic heterogeneity among clonal isolates of -4

Uption of linkage is apparent among members the same CC that share the same loci.<p><b>Copyright information:</b></p><p>Taken from "Comparative genomic assessment of Multi-Locus Sequence Typing: rapid accumulation of genomic heterogeneity among clonal isolates of "</p><p>http://www.biomedcentral.com/1471-2148/8/229</p><p>BMC Evolutionary Biology 2008;8():229-229.</p><p>Published online 8 Aug 2008</p><p>PMCID:PMC2527321.</p><p></p

Comparative genomic assessment of Multi-Locus Sequence Typing: rapid accumulation of genomic heterogeneity among clonal isolates of -3

hyper-variable loci in the genome (B). Mosaicism observed in the CGH data is consistent with that observed in newly sequenced genomes (C). (note: Log Ratio data in (A) and (B) and sequence identity data in (C) were colour coded using a common scale reflecting the likelihood of gene presence/absence).<p><b>Copyright information:</b></p><p>Taken from "Comparative genomic assessment of Multi-Locus Sequence Typing: rapid accumulation of genomic heterogeneity among clonal isolates of "</p><p>http://www.biomedcentral.com/1471-2148/8/229</p><p>BMC Evolutionary Biology 2008;8():229-229.</p><p>Published online 8 Aug 2008</p><p>PMCID:PMC2527321.</p><p></p

Comparative genomic assessment of Multi-Locus Sequence Typing: rapid accumulation of genomic heterogeneity among clonal isolates of -5

boxed in red. Allelic differences with respect to the central sequence type (ST) of the CC are highlighted in blue.<p><b>Copyright information:</b></p><p>Taken from "Comparative genomic assessment of Multi-Locus Sequence Typing: rapid accumulation of genomic heterogeneity among clonal isolates of "</p><p>http://www.biomedcentral.com/1471-2148/8/229</p><p>BMC Evolutionary Biology 2008;8():229-229.</p><p>Published online 8 Aug 2008</p><p>PMCID:PMC2527321.</p><p></p

Comparative genomic assessment of Multi-Locus Sequence Typing: rapid accumulation of genomic heterogeneity among clonal isolates of -0

boxed in red. Allelic differences with respect to the central sequence type (ST) of the CC are highlighted in blue.<p><b>Copyright information:</b></p><p>Taken from "Comparative genomic assessment of Multi-Locus Sequence Typing: rapid accumulation of genomic heterogeneity among clonal isolates of "</p><p>http://www.biomedcentral.com/1471-2148/8/229</p><p>BMC Evolutionary Biology 2008;8():229-229.</p><p>Published online 8 Aug 2008</p><p>PMCID:PMC2527321.</p><p></p

Comparative genomic assessment of Multi-Locus Sequence Typing: rapid accumulation of genomic heterogeneity among clonal isolates of -2

L other strains in the dataset and differentiate this group of genetically related strains from other groups of strains.<p><b>Copyright information:</b></p><p>Taken from "Comparative genomic assessment of Multi-Locus Sequence Typing: rapid accumulation of genomic heterogeneity among clonal isolates of "</p><p>http://www.biomedcentral.com/1471-2148/8/229</p><p>BMC Evolutionary Biology 2008;8():229-229.</p><p>Published online 8 Aug 2008</p><p>PMCID:PMC2527321.</p><p></p

Comparative genomic analysis of associated with Guillain-Barré and Miller Fisher syndromes: neuropathogenic and enteritis-associated isolates can share high levels of genomic similarity-0

<p><b>Copyright information:</b></p><p>Taken from "Comparative genomic analysis of associated with Guillain-Barré and Miller Fisher syndromes: neuropathogenic and enteritis-associated isolates can share high levels of genomic similarity"</p><p>http://www.biomedcentral.com/1471-2164/8/359</p><p>BMC Genomics 2007;8():359-359.</p><p>Published online 5 Oct 2007</p><p>PMCID:PMC2174954.</p><p></p>how unique gene conservation profiles and fail to cluster robustly with any major lineage. Branches with greater than 75% bootstrap support are shown in red. Although data is displayed including capsular genes (gray box), these genes were removed during cluster analysis to avoid biasing results. Highly divergent/Absent genes shown in red; Moderately Divergent genes are shown in blue. Legend: Hypervariable loci (L – LOS locus; F – flagellar modification locus; C – capsular locus; R/M – restriction-modification locus); Strain sets (DG: Dutch GBS; DM: Dutch MFS; JG: Japanese GBS; JM: Japanese MFS; CG: Curaçao GBS)

Comparative genomic analysis of associated with Guillain-Barré and Miller Fisher syndromes: neuropathogenic and enteritis-associated isolates can share high levels of genomic similarity-4

<p><b>Copyright information:</b></p><p>Taken from "Comparative genomic analysis of associated with Guillain-Barré and Miller Fisher syndromes: neuropathogenic and enteritis-associated isolates can share high levels of genomic similarity"</p><p>http://www.biomedcentral.com/1471-2164/8/359</p><p>BMC Genomics 2007;8():359-359.</p><p>Published online 5 Oct 2007</p><p>PMCID:PMC2174954.</p><p></p> neuropathogenic strains. Both types of strains can show substantial similarities in genomic background, which includes similarities at several hypervariable regions. The lineage (LIN) of the 56 neuropathogenic strains is shown. Highly similar enteritis-control/neuropathogenic strain pairs (boxes a through d) are shown in expanded form in Figure 3. Legend: Hypervariable loci (L – LOS locus; F – flagellar modification locus; C – capsular locus; R/M – restriction-modification locus); Strain sets (DG: Dutch GBS; DM: Dutch MFS; DE: Dutch enteritis; JG: Japanese GBS; JM: Japanese MFS; JE: Japanese enteritis; CG: Curaçao GBS; CE: Curaçao enteritis)

Comparative genomic analysis of associated with Guillain-Barré and Miller Fisher syndromes: neuropathogenic and enteritis-associated isolates can share high levels of genomic similarity-1

<p><b>Copyright information:</b></p><p>Taken from "Comparative genomic analysis of associated with Guillain-Barré and Miller Fisher syndromes: neuropathogenic and enteritis-associated isolates can share high levels of genomic similarity"</p><p>http://www.biomedcentral.com/1471-2164/8/359</p><p>BMC Genomics 2007;8():359-359.</p><p>Published online 5 Oct 2007</p><p>PMCID:PMC2174954.</p><p></p> neuropathogenic strains. Both types of strains can show substantial similarities in genomic background, which includes similarities at several hypervariable regions. The lineage (LIN) of the 56 neuropathogenic strains is shown. Highly similar enteritis-control/neuropathogenic strain pairs (boxes a through d) are shown in expanded form in Figure 3. Legend: Hypervariable loci (L – LOS locus; F – flagellar modification locus; C – capsular locus; R/M – restriction-modification locus); Strain sets (DG: Dutch GBS; DM: Dutch MFS; DE: Dutch enteritis; JG: Japanese GBS; JM: Japanese MFS; JE: Japanese enteritis; CG: Curaçao GBS; CE: Curaçao enteritis)

Comparative genomics profiling of clinical isolates of using DNA microarrays-4

<p><b>Copyright information:</b></p><p>Taken from "Comparative genomics profiling of clinical isolates of using DNA microarrays"</p><p>BMC Genomics 2006;7():43-43.</p><p>Published online 7 Mar 2006</p><p>PMCID:PMC1434746.</p><p>Copyright © 2006 Nash et al; licensee BioMed Central Ltd.</p>n size. The amplicons were "binned" in 50 bp increments (to 1900 bp) then in 200 bp increments (from 2000 to 3000 bp). There were only 4 amplicons of size over 3000 bp