Temporal variation of mean temperature over the period studied.

<p>Temporal variation of mean temperature over the period studied.</p

Temporal variation of minimum temperature over the period studied.

<p>Temporal variation of minimum temperature over the period studied.</p

Predicted annual disease cases from the final model (M5) together with the observed/reported number of cases.

<p>Predicted annual disease cases from the final model (M5) together with the observed/reported number of cases.</p

Time series of annual incidence of dengue in Singapore, 1974–2011.

<p>Time series of annual incidence of dengue in Singapore, 1974–2011.</p

Estimates of Regression coeficients of the best fitting model (M5).

<p>Estimates of Regression coeficients of the best fitting model (M5).</p

Relative risks and associated risk fractions (%) associated with each driver associated with the trend change in that specific variables over the study period.

<p>Relative risks and associated risk fractions (%) associated with each driver associated with the trend change in that specific variables over the study period.</p

Model comparison.

<p>Note: M1- model complete with all variables expressed with their original values; M2 –variables maxT, minT, meanT and premise replaced by the scores in PCA1 and PCA2; M3 –same as M1 but dropping the autoregressive component; M4 –same as M1 but dropping the cyclic component; M5 –same as M1 but removing the variables that did not achieve significance (maxT); <i>β</i>pop, S.E., Wald Z and p-values refer to the estimates of <i>β</i> for variable “Total Population” under the various models.</p><p>Model comparison.</p

Temporal variation of population size over the period studied.

<p>Temporal variation of population size over the period studied.</p

Independent Variables of the Poisson Regression Model with the respective coefficients and incidence ratios.

<p>Independent Variables of the Poisson Regression Model with the respective coefficients and incidence ratios.</p

Descriptive statistics of the studied variables (N = 60).

<p>Descriptive statistics of the studied variables (N = 60).</p