70 research outputs found
Inert coupling of IRDye800CW to monoclonal antibodies for clinical optical imaging of tumor targets
Imaging- and therapeutic targets in neoplastic and musculoskeletal inflammatory diseas
Effect of adjuvant trastuzumab treatment in conventional clinical setting: an observational retrospective multicenter Italian study
Functional outcomes following post-acute rehabilitation for moderate-to-severe traumatic brain injury
Impact of 68Ga-NOTA-MAL-MZHER2 PET imaging in advanced gastric cancer patients and therapeutic response monitoring
Multimodal image-guided surgery of HER2-positive breast cancer using [111In]In-DTPA-trastuzumab-IRDye800CW in an orthotopic breast tumor model
Mucolytic Agents Can Enhance HER2 Receptor Accessibility for [89Zr]Trastuzumab, Improving HER2 Imaging in a Mucin-Overexpressing Breast Cancer Xenograft Mouse Model
Binding of trastuzumab to HER2 receptors can be impaired by steric hindrance caused by mucin MUC4. As mucolytic drugs can breakdown disulfide bonds of mucoproteins, we checked if this approach could positively affect zirconium-89-labeled trastuzumab ([(89)Zr]T) binding/uptake.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
First In-Human Medical Imaging with a PASylated 89Zr-Labeled Anti-HER2 Fab-Fragment in a Patient with Metastatic Breast Cancer
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