836 research outputs found

    Knowledge of an Aboriginal language and school outcomes for children and adults

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    This study uses data from the child and adult components of the 2001 Canadian Aboriginal Peoples Survey to examine what factors are related to speaking an Aboriginal language and how speaking an Aboriginal language is related to school outcomes. Even after controlling for child and family factors (age, sex, health status, household income, number of people living in the household, and living in an urban or rural area), speaking an Aboriginal language was associated with positive school outcomes for young children aged 6 to 14 years old if they learned the language in school, but a lower likelihood of having completed high school for 20 to 34-year olds. Possible reasons for this difference between child and adult results are discussed

    Antipsychotic treatments for the elderly: efficacy and safety of aripiprazole

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    Delusions, hallucinations and other psychotic symptoms can accompany a number of conditions in late life. As such, elderly patients are commonly prescribed antipsychotic medications for the treatment of psychosis in both acute and chronic conditions. Those conditions include schizophrenia, bipolar disorder, depression and dementia. Elderly patients are at an increased risk of adverse events from antipsychotic medications because of age-related pharmacodynamic and pharmacokinetic changes as well as polypharmacy. Drug selection should be individualized to the patient’s previous history of antipsychotic use, current medical conditions, potential drug interactions, and potential side effects of the antipsychotic. Specifically, metabolic side effects should be closely monitored in this population. This paper provides a review of aripiprazole, a newer second generation antipsychotic agent, for its use in a variety of psychiatric disorders in the elderly including schizophrenia, bipolar disorder, dementia, Parkinson’s disease and depression. We will review the pharmacokinetics and pharmacodynamics of aripiprazole as well as dosing, diagnostic indications, efficacy studies, and tolerability including its metabolic profile. We will also detail patient focused perspectives including quality of life, patient satisfaction and adherence

    What Statistics Canada Survey Data Sources are Available to Study Neurodevelopmental Conditions and Disabilities in Children and Youth?

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    Researchers with an interest in examining and better understanding the social context of children suffering from neurodevelopmental disabilities can benefit by using data from a wide variety of Statistics Canada surveys as well as the information contained in administrative health databases. Selective use of a particular survey and database can be informative particularly when demographics, samples, and content align with the goals and outcomes of the researcher’s questions of interest. Disabilities are not merely conditions in isolation. They are a key part of a social context involving impairment, function, and social facilitators or barriers, such as work, school and extracurricular activities. Socioeconomic factors, single parenthood, income, and education also play a role in how families cope with children’s disabilities. Statistics indicate that five per cent of Canadian children aged five to 14 years have a disability, and 74 per cent of these are identified as having a neurodevelopmental condition and disability. A number of factors must be taken into account when choosing a source of survey data, including definitions of neurodevelopmental conditions, the target group covered by the survey, which special populations are included or excluded, along with a comparison group, and the survey’s design. Surveys fall into categories such as general health, disability-specific, and children and youth. They provide an excellent opportunity to look at the socioeconomic factors associated with the health of individuals, as well as how these conditions and disabilities affect families. However rich the information gleaned from survey data, it is not enough, especially given the data gaps that exist around the health and well-being of children and older youths. This is where administrative and other data can be used to complement existing data sources. Administrative data offer specific information about neurological conditions that won’t be collected in general population surveys, given the nature of such surveys. While researchers can glean information from survey data such as functional health and disability, social inclusion or exclusion, and the role of social determinants in the lives of these children and their families, administrative data can identify rare neurodevelopmental conditions and disabilities not captured in general surveys. Analyzing information from all these sources can lead to a more nuanced understanding of the economic and social impacts, and functional limitations in daily living, that patients and their families experience with certain neurodevelopmental conditions and disabilities. Statistics Canada surveys offer a plethora of information for researchers interested in neurodevelopmental disabilities and social determinants of health. As these surveys are national in their scope, they provide a wealth of information for statistical analysis from people across Canada. This information can be used to inform researchers, policy makers, and families of people who live with neurodevelopmental conditions and disabilities. For example, sophisticated microsimulation modelling techniques have been conducted to project the health and economic impacts from such disabilities 20 years into the future. Such projections will be vital for policy-makers tasked with designing services and programs to assist these people. Much work remains to be done, however. Statistics Canada has already begun working on the potential for using administrative data to conceptualize childhood disability, as well as using data that has been anonymized in national administrative databases to study the health of Canada’s children. These are excellent bases from which to build future research

    Participation in Physical Activity for Children with Neurodevelopmental Disorders

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    The purpose of this study was to compare rates of participation for children (4–9 years of age) with neurodevelopmental disorders (NDDs) with and without externalizing behavior problems (EBPs) with children without disability and to examine mediators of the relation between disability and physical activity participation. Data for this study were drawn from Cycle 7 (2006-07) of the Canadian National Longitudinal Survey of Children and Youth (NLSCY). The frequency of children's participation in organized sports or physical activities varied depending on the child's health condition with children with NDDs and both NDDs and EBPs participating least in organized sports or physical activities followed by children with EBPs only. In contrast, there were no statistically significant differences by health group for children's participation in unorganized sports or physical activities. These differences remained even after controlling for the effects of other child and family sociodemographic characteristics, except for children with EBPs only. These findings highlight the importance of considering children's primary and other existing health conditions as well as family sociodemographic characteristics in order to better understand the factors that influence participation in organized physical activities for children with disabilities

    Linking Culture and Language to Aboriginal Children’s Outcomes: Lessons from Canadian Data

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    Aboriginal children have been shown to have poorer health and educational outcomes compared to non-Aboriginal children. Culture is an important determinant of health and well-being, yet it is rarely studied in terms of its association with young children’s outcomes. Language being one component of culture, the revitalization of traditional Aboriginal languages is an important contributor to both individual and community health as well as educational achievement. This paper will summarize multiple studies using data from the Aboriginal Children’s Survey and the Aboriginal Peoples Survey to highlight various outcomes for Aboriginal children in Canada, first in terms of the role of cultural participation, and then specifically speaking an Aboriginal language, on young Aboriginal children’s education and health outcomes. ----- Il a Ă©tĂ© dĂ©montrĂ© ailleurs que les enfants autochtones sont en moins bonne santĂ© et ont des rĂ©sultats scolaires plus faibles relativement aux enfants non autochtones. La culture est un dĂ©terminant important de la santĂ© et du bien-ĂȘtre, mais on ne l’étudie que rarement en fonction de son association aux rĂ©sultats scolaires chez les jeunes enfants. La langue Ă©tant un des constituants de la culture, la revitalisation des langues autochtones traditionnelles est un contributeur important Ă  la santĂ© individuelle et communautaire ainsi qu’à la rĂ©ussite scolaire. Cet article rĂ©sume plusieurs Ă©tudes en utilisant les donnĂ©es de l’EnquĂȘte sur les enfants autochtones et l’EnquĂȘte auprĂšs des peuples autochtones pour mettre en Ă©vidence divers rĂ©sultats sur l’éducation et la santĂ© pour les enfants autochtones au Canada – d’abord en termes du rĂŽle de la participation culturelle, puis en ciblant ceux qui parlent une langue autochtone particuliĂšre

    Reply to Comment on "Completely positive quantum dissipation"

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    This is the reply to a Comment by R. F. O'Connell (Phys. Rev. Lett. 87 (2001) 028901) on a paper written by the author (B. Vacchini, ``Completely positive quantum dissipation'', Phys.Rev.Lett. 84 (2000) 1374, arXiv:quant-ph/0002094).Comment: 2 pages, revtex, no figure

    Symmetry and Temperature dependence of the Order parameter in MgB2 from point contact measurements

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    We have performed differential conductance versus voltage measurements of Au/MgB2 point contacts. We find that the dominant component in the conductance is due to Andreev reflection. The results are fitted to the theoretical model of BTK for an s-wave symmetry from which we extract the value of the order parameter (Delta) and its temperature dependence. From our results we also obtain a lower experimental bound on the Fermi velocity in MgB2.Comment: 7 pages (Including figure captions) and 4 figure

    Conceptualizing childhood health problems using survey data: a comparison of key indicators

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    <p>Abstract</p> <p>Background</p> <p>Many definitions are being used to conceptualize child health problems. With survey data, commonly used indicators for identifying children with health problems have included chronic condition checklists, measures of activity limitations, elevated service use, and health utility thresholds. This study compares these different indicators in terms of the prevalence rates elicited, and in terms of how the subgroups identified differ.</p> <p>Methods</p> <p>Secondary data analyses used data from the National Longitudinal Survey of Children and Youth, which surveyed a nationally representative sample of Canadian children (n = 13,790). Descriptive analyses compared healthy children to those with health problems, as classified by any of the key indicators. Additional analyses examined differences between subgroups of children captured by a single indicator and those described as having health problems by multiple indicators.</p> <p>Results</p> <p>This study demonstrates that children captured by any of the indicators had poorer health than healthy children, despite the fact that over half the sample (52.2%) was characterized as having a health problem by at least one indicator. Rates of child ill health differed by indicator; 5.6% had an activity limitation, 9.2% exhibited a severe health difficulty, 31.7% reported a chronic condition, and 36.6% had elevated service use. Further, the four key indicators captured different types of children. Indicator groupings differed on child and socio-demographic factors. Compared to children identified by more than one indicator, those identified only by the severe health difficulty indicator displayed more cognitive problems (p < 0.0001), those identified only by the chronic condition checklist had a greater likelihood of reporting allergies or asthma (p < 0.0001), and those identified as having elevated service use only were more affluent (p = 0.01) and showed better overall health (p < 0.0001). Children identified by only a single indicator were less likely to have serious health problems than those identified by two or more indicators.</p> <p>Conclusion</p> <p>We provide information useful to researchers when selecting indicators from survey data to identify children with health problems. Researchers and policy makers need to be aware of the impact of such definitions on prevalence rates as well as on the composition of children classified as being in poor health.</p

    Local and macroscopic tunneling spectroscopy of Y(1-x)CaxBa2Cu3O(7-d) films: evidence for a doping dependent is or idxy component in the order parameter

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    Tunneling spectroscopy of epitaxial (110) Y1-xCaxBa2Cu3O7-d films reveals a doping dependent transition from pure d(x2-y2) to d(x2-y2)+is or d(x2-y2)+idxy order parameter. The subdominant (is or idxy) component manifests itself in a splitting of the zero bias conductance peak and the appearance of subgap structures. The splitting is seen in the overdoped samples, increases systematically with doping, and is found to be an inherent property of the overdoped films. It was observed in both local tunnel junctions, using scanning tunneling microscopy (STM), and in macroscopic planar junctions, for films prepared by either RF sputtering or laser ablation. The STM measurements exhibit fairly uniform splitting size in [110] oriented areas on the order of 10 nm2 but vary from area to area, indicating some doping inhomogeneity. U and V-shaped gaps were also observed, with good correspondence to the local faceting, a manifestation of the dominant d-wave order parameter

    Superconductivity of the Sr2Ca12Cu24O41Sr_2 Ca_{12} Cu_{24} O_{41} spin ladder system: Are the superconducting pairing and the spin-gap formation of the same origin?

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    Pressure-induced superconductivity in a spin-ladder cuprate Sr2_2Ca12_{12}Cu24_{24}O41_{41} has not been studied on a microscopic level so far although the superconductivity was already discovered in 1996. We have improved high-pressure technique with using a large high-quality crystal, and succeeded in studying the superconductivity using 63^{63}Cu nuclear magnetic resonance (NMR). We found that anomalous metallic state reflecting the spin-ladder structure is realized and the superconductivity possesses a s-wavelike character in the meaning that a finite gap exists in the quasi-particle excitation: At pressure of 3.5GPa we observed two excitation modes in the normal state from the relaxation rate T1−1T_1^{-1}. One gives rise to an activation-type component in T1−1T_1^{-1}, and the other TT-linear component linking directly with the superconductivity. This gapless mode likely arises from free motion of holon-spinon bound states appearing by hole doping, and the pairing of them likely causes the superconductivity.Comment: to be published in Phys. Rev. Let
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