UW School of Music Scholarship Celebration November 3, 2013

Concert ProgramUW School of Music Scholarship Celebration November 3, 201

Music and Print

This chapter surveys some of the major trends in music printing and publishing from the fifteenth century to the present day. From Ottaviano Petrucci's introduction of triple‐impression printing for polyphonic music in the sixteenth century to the global marketing of music in modern times, the history of music in print reveals an uneven correlation between technological development, socioeconomic change, and notational evolution. Owing to the unique spatial and performative dimensions to the musical text, the music publisher plays an unusually significant role in mediating between the composer and intended audience. Music therefore offers an illuminating and challenging area for bibliographical exploration

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

We performed a meta-analysis of five genome-wide association studies to identify common variants influencing colorectal cancer (CRC) risk comprising 8,682 cases and 9,649 controls. Replication analysis was performed in case-control sets totaling 21,096 cases and 19,555 controls. We identified three new CRC risk loci at 6p21 (rs1321311, near CDKN1A; P = 1.14 × 10 -10), 11q13.4 (rs3824999, intronic to POLD3; P = 3.65 × 10 -10) and Xp22.2 (rs5934683, near SHROOM2; P = 7.30 × 10 -10) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC.</p